Time to a Negative SARS-CoV-2 PCR Predicts Delayed Return to Work After Medical Leave in COVID-19 Infected Health Care Workers.
Journal
Journal of occupational and environmental medicine
ISSN: 1536-5948
Titre abrégé: J Occup Environ Med
Pays: United States
ID NLM: 9504688
Informations de publication
Date de publication:
01 11 2021
01 11 2021
Historique:
pubmed:
30
7
2021
medline:
12
11
2021
entrez:
29
7
2021
Statut:
ppublish
Résumé
To investigate whether HCWs return to work (RTW) after COVID-19 was associated with time to a negative viral detection test. To evaluate the association of RTW with an undetectable RT-PCR adjusting for different factors. Three hundred seventy-five HCWs who required medical leave for COVID-19 at a hospital in Madrid. Multivariable analyses confirmed the association of delayed RTW with interval to negative PCR (ORadj 1.12, 95% CI 1.08, 1.17) as well as age, sex, and nursing staff and clinical support services compared to physicians. A predictive model based on those variables is proposed, which had an area under the receiver operating curve of 0.82. Delayed RTW was associated with longer interval to a negative RT-PCR after symptom onset, adjusting for occupational category, age, and sex.
Identifiants
pubmed: 34325436
doi: 10.1097/JOM.0000000000002336
pii: 00043764-202111000-00010
pmc: PMC8562925
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
970-974Informations de copyright
Copyright © 2021 American College of Occupational and Environmental Medicine.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
Johns Hopkins University Center for Systems Science and Engineering. COVID-19 Dashboard 2020. https://coronavirus.jhu.edu/map.html [accessed on 8-October-2020].
Trajman A, Menzies D. Occupational respiratory infections. Curr Opin Pulm Med 2010; 16:226–234.
Carlsten C, Gulati M, Hines S, et al. COVID-19 as an occupational disease. Am J Ind Med 2021; 64:227–237.
Health NYC. Age-adjusted Rates of Lab-confirmed COVID-19 Non-hospitalized Cases, Estimated Non-fatal Hospitalized Cases, and Patients Known to Have Died 100,000 by Race/Ethnicity Group as of April 27. XXXX 2020; 2020:
Baker MG, Peckham TK, Seixas NS. Estimating the burden of United States workers exposed to infection or disease: a key factor in containing risk of COVID-19 infection. PLoS One 2020; 15:e0232452.
Hawkins D. Differential occupational risk for COVID-19 and other infection exposure according to race and ethnicity. Am J Ind Med 2020; 63:817–820.
Pan A, Liu L, Wang C, et al. Association of public health interventions with the epidemiology of the COVID-19 outbreak in Wuhan, China. JAMA 2020; 323:1915–1923.
Nguyen LH, Drew DA, Graham MS, et al. Risk of COVID-19 among front-line health-care workers and the general community: a prospective cohort study. Lancet Public Health 2020; 5:e475–e483.
Chou R, Dana T, Buckley DI, Selph S, Fu R, Totten AM. Epidemiology of and risk factors for coronavirus infection in health care workers: a living rapid review. Ann Intern Med 2020; 173:120–136.
Hyman MH, Talmage JB, Hegmann KT. Evaluating COVID-19 injury claims with a focus on workers’ compensation. J Occup Environ Med 2020; 62:692–699.
Troyer EA, Kohn JN, Hong S. Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? Neuropsychiatric symptoms and potential immunologic mechanisms. Brain Behav Immun 2020; 87:34–39.
Zhao YM, Shang YM, Song WB, et al. Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery. EClinicalMedicine 2020; 25:100463.
Spagnolo P, Balestro E, Aliberti S, et al. Pulmonary fibrosis secondary to COVID-19: a call to arms? Lancet Respir Med 2020; 8:750–752.
Guzik TJ, Mohiddin SA, Dimarco A, et al. COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options. Cardiovasc Res 2020; 116:1666–1687.
Candan SA, Elibol N, Abdullahi A. Consideration of prevention and management of long-term consequences of post-acute respiratory distress syndrome in patients with COVID-19. Physiother Theory Pract 2020; 36:663–668.
Rueda Garrido JC, Vicente Herrero TV, del Campo MT, et al. Return to work guidelines for the COVID-19 pandemic. Occup Med (Lond) 2020; 70:300–305.
Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40:373–383.
Moltó A, Dougados M. Comorbidity indices. Clin Exp Rheumatol 2014; 32:S131–S134.
James G, Witten D, Hastie T, Tibshirani R. James G, Witten D, Hastie T, Tibshirani R. Resampling methods. An Introduction to Statistical Learning: with applications in R . New York: Springer; 2013. 175–202.
Ganz-Lord FA, Segal KR, Rinke ML. Covid-19 symptoms, duration, and prevalence among healthcare workers in the New York metropolitan area. Infect Control Hosp Epidemiol 2020; 42:917–923.
Suárez-García I, Martínez de Aramayona López MJ, Sáez Vicente A, Lobo Abascal P. SARS-CoV-2 infection among healthcare workers in a hospital in Madrid, Spain. J Hosp Infect 2020; 106:357–363.
Chinese Center for Disease Control and Prevention. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua Liu Xing Bing Xue Za Zhi 2020; 41:145–151.
Centers for Disease Control and Prevention. Characteristics of health care personnel with COVID-19 – United States, February 12–April 9, 2020. Morb Mortal Wkly Rep 2020; 69:477–481.23.
Equipo COVID-19 – Red Nacional de Vigilancia Epidemiológica. Análisis de los casos de COVID-19 en personal sanitario notificados a la RENAVE hasta el 10 de mayo en España. 2020; Madrid, Spain: Red Nacional de Vigilancia Epidemiológica, 1–11.
Alwan NA, Johnson D. Defining long COVID: going back to the start. Med (N Y) 2021; 2:501–504. DOI 10. 1016/j. medj.2021.03. 003.
Centers for Disease Control and Prevention. Severe outcomes among patients with coronavirus disease 2019 (COVID-19) – United States, February 12–March 16. Morb Mortal Wkly Rep 2020; 69:343–346.
Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395:1054–1062.
Du Y, Tu L, Zhu P, et al. Clinical features of 85 fatal cases of COVID-19 from Wuhan: a retrospective observational study. Am J Respir Crit Care Med 2020; 201:1372–1379.
Buerhaus PI, Auerbach DI, Staiger DO. Older clinicians and the surge in novel coronavirus disease 2019 (COVID-19). JAMA 2020; 323:1777–1778.
Lai R, Tan L, Lai X, Zhang X, Zhou Q. Help-seeking behavior of returning to work in healthcare workers and its influencing factors during COVID-19 subsiding. J Occup Environ Med 2020; 62:898–903.
Fennelly KP. Particle sizes of infectious aerosols: implications for infection control. Lancet Respir Med 2020; 8:914–924.
Chow EJ, Schwartz NG, Tobolowsky FA, et al. Symptom screening at illness onset of health care personnel with SARS-CoV-2 infection in King County, Washington. JAMA 2020; 323:2087–2089.