Primary ectopic axillary breast cancer: a case series.
Carcinoma
Chemotherapy
Ectopic breast tissue
Hormonotherapy
Radiotherapy
Surgery
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
31 Jul 2021
31 Jul 2021
Historique:
received:
11
02
2021
accepted:
29
06
2021
entrez:
31
7
2021
pubmed:
1
8
2021
medline:
4
8
2021
Statut:
epublish
Résumé
Ectopic breast tissue is present in 2-6% of women. Ectopic breast cancer represents an uncommon disease accounting for about 0.3% of all breast neoplasms, limiting the available evidence. Thus, we aim to report long-term outcomes in five cases treated at our institution. Our Tunisian patients' median age was 48 years (33-60 years), and the median follow-up was 8 years (4-10 years). The ectopic breast tissue was located four times in the right axilla. The median tumor size was 25 mm (15-55 mm). Four of the patients underwent a wide local excision and axillary lymph node dissection. Three of those women had positive lymph nodes; thus, they received adjuvant chemotherapy, radiation therapy, and hormone therapy. The patient with a negative lymph node (case 5) had adjuvant radiation therapy and hormonal therapy. One of the patients (case 1) had a positive supraclavicular lymph node and received radiation therapy, chemotherapy, and hormonal therapy. The latter developed a locoregional relapse after 4 years and was treated with mastectomy and chemotherapy. One patient (case 4) had a distant metastasis after 2 years of follow-up and received chemotherapy. The three other patients were free of relapse during their follow-up period. Primary axillary breast carcinoma is a rare entity. Despite the paucity of literature, our findings and authors' recommendations suggest that local excision can be performed safely with promising outcomes in this subset of patients.
Identifiants
pubmed: 34330331
doi: 10.1186/s13256-021-02998-w
pii: 10.1186/s13256-021-02998-w
pmc: PMC8325209
doi:
Types de publication
Journal Article
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
412Informations de copyright
© 2021. The Author(s).
Références
Dermatol Surg. 2005 Feb;31(2):237-9
pubmed: 15762222
Surg Oncol. 1994 Oct;3(5):295-304
pubmed: 7889223
Pan Afr Med J. 2012;13:50
pubmed: 23330041
Surg Oncol. 2011 Mar;20(1):35-42
pubmed: 19853438
Am Surg. 1961 May;27:388-90
pubmed: 13694314
Ann Dermatol Venereol. 2002 Dec;129(12):1389-91
pubmed: 12536178
Acta Cytol. 1995 Sep-Oct;39(5):941-4
pubmed: 7571974
J Korean Med Sci. 2001 Aug;16(4):519-21
pubmed: 11511802
Breast Cancer. 1997 Mar 25;4(1):43-48
pubmed: 11091576
Int J Gynecol Cancer. 2006 Jan-Feb;16 Suppl 1:423-8
pubmed: 16515638
Aesthetic Plast Surg. 2013 Aug;37(4):746-9
pubmed: 23620009
Arch Pathol Lab Med. 2001 Oct;125(10):1372-4
pubmed: 11570920
Ann Chir Plast Esthet. 1991;36(5):457-9
pubmed: 1726395
J Natl Med Assoc. 1982 Jan;74(1):37-8
pubmed: 7120440
Radiology. 1987 Jun;163(3):709-11
pubmed: 3575719
BMJ Case Rep. 2019 Jan 24;12(1):
pubmed: 30679228
Breast J. 2002 Sep-Oct;8(5):286-9
pubmed: 12199756
Trop Geogr Med. 1984 Mar;36(1):45-9
pubmed: 6328710
J Am Acad Dermatol. 2003 Dec;49(6):1154-6
pubmed: 14639406
Anticancer Res. 1998 Sep-Oct;18(5B):3737-40
pubmed: 9854486
J Surg Oncol. 1995 Jul;59(3):190-5
pubmed: 7609527
J Plast Reconstr Aesthet Surg. 2011 Jan;64(1):e1-11
pubmed: 20934398
Am Surg. 2004 Apr;70(4):312-5
pubmed: 15098783
Diagn Gynecol Obstet. 1982 Summer;4(2):141-5
pubmed: 6284467
Minerva Ginecol. 1984 Oct;36(10):623
pubmed: 6527816
Oncol Rep. 1998 Mar-Apr;5(2):413-7
pubmed: 9468570
Cancer. 1976 Dec;38(6):2570-4
pubmed: 187318
Surg Clin North Am. 1950 Dec;30(6):1717-41
pubmed: 14787886