A novel use for routine CBCT imaging during radiotherapy to detect COVID-19.
CBCT
COVID-19 corona virus
Cone-beam CT
Radiotherapy
Journal
Radiography (London, England : 1995)
ISSN: 1532-2831
Titre abrégé: Radiography (Lond)
Pays: Netherlands
ID NLM: 9604102
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
02
03
2021
revised:
21
06
2021
accepted:
11
07
2021
pubmed:
2
8
2021
medline:
14
1
2022
entrez:
1
8
2021
Statut:
ppublish
Résumé
Thoracic CT is a useful tool in the early diagnosis of patients with COVID-19. Typical appearances include patchy ground glass shadowing. Thoracic radiotherapy uses daily cone beam CT imaging (CBCT) to check for changes in patient positioning and anatomy prior to treatment through a qualitative assessment of lung appearance by radiographers. Observation of changes related to COVID-19 infection during this process may facilitate earlier testing improving patient management and staff protection. A tool was developed to create overview reports for all CBCTs for each patient throughout their treatment. Reports contain coronal maximum intensity projection (MIP's) of all CBCTs and plots of lung density over time. A single therapeutic radiographer undertook a blinded off-line audit that reviewed 150 patient datasets for tool optimisation in which medical notes were compared to image findings. This cohort included 75 patients treated during the pandemic and 75 patients treated between 2014 and 2017. The process was repeated retrospectively on a subset of the 285 thoracic radiotherapy patients treated between January-June 2020 to assess the efficiency of the tool and process. Three patients in the n = 150 optimisation cohort had confirmed COVID-19 infections during their radiotherapy. Two of these were detected by the reported image assessment process. The third case was not detected on CBCT due to minimal density changes in the visible part of the lungs. Within the retrospective cohort four patients had confirmed COVID-19 based on RT-PCR tests, three of which were retrospectively detected by the reported process. The preliminary results indicate that the presence of COVID-19 can be detected on CBCT by therapeutic radiographers. This process has now been extended to clinical service with daily assessments of all thoracic CBCTs. Changes noted are referred for oncologist review.
Identifiants
pubmed: 34332857
pii: S1078-8174(21)00091-2
doi: 10.1016/j.radi.2021.07.011
pmc: PMC8299223
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
17-23Informations de copyright
Copyright © 2021 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of interest statement None.
Références
Med Phys. 2013 Jun;40(6):060701
pubmed: 23718579
Indian J Pediatr. 2020 Apr;87(4):281-286
pubmed: 32166607
AJR Am J Roentgenol. 2020 Jun;214(6):1280-1286
pubmed: 32130038
Respir Med. 2020 Jul;168:105980
pubmed: 32364959
Dent Clin North Am. 2008 Oct;52(4):707-30, v
pubmed: 18805225
Radiol Cardiothorac Imaging. 2020 Apr 07;2(2):e204002
pubmed: 33779623
Infect Dis Poverty. 2020 Mar 17;9(1):29
pubmed: 32183901
Cancer Detect Prev. 2005;29(2):181-8
pubmed: 15829379
Ann Oncol. 2020 Jul;31(7):894-901
pubmed: 32224151
Rep Pract Oncol Radiother. 2015 Sep-Oct;20(5):328-39
pubmed: 26549990
AJR Am J Roentgenol. 2020 Aug;215(2):367-373
pubmed: 32223665
Cureus. 2019 Nov 11;11(11):e6120
pubmed: 31886058
AJR Am J Roentgenol. 2009 May;192(5):1324-9
pubmed: 19380557
BMJ. 2020 Mar 26;368:m1198
pubmed: 32217618
Lancet Infect Dis. 2020 Apr;20(4):425-434
pubmed: 32105637
JAMA. 2020 Apr 14;323(14):1406-1407
pubmed: 32083643
Adv Radiat Oncol. 2020 May 20;5(4):707-710
pubmed: 32775778
Lancet Oncol. 2020 Oct;21(10):1309-1316
pubmed: 32853557
Br J Radiol. 2016 Jun;89(1062):20150492
pubmed: 27052681
Dermatol Ther. 2020 Nov;33(6):e13859
pubmed: 32559324
Lancet Oncol. 2020 Apr;21(4):e180
pubmed: 32142622
Oncology. 2005;69(3):214-23
pubmed: 16127290
Pediatr Radiol. 2013 Jul;43(7):820-6
pubmed: 23344916
Radiology. 2020 Aug;296(2):E32-E40
pubmed: 32101510
Adv Radiat Oncol. 2020 May 19;5(4):715-721
pubmed: 32775781
J Thorac Oncol. 2020 Jun;15(6):1081-1084
pubmed: 32283316