Instability in NAD
Animals
DNA Damage
DNA Repair
DNA, Mitochondrial
/ metabolism
HeLa Cells
Heart
/ physiopathology
Heart Diseases
/ physiopathology
Humans
Mice
Mitochondria
/ metabolism
Myocardium
/ metabolism
NAD
/ metabolism
Niacinamide
/ adverse effects
Pyridinium Compounds
/ adverse effects
Sirtuins
/ antagonists & inhibitors
DNA repair
NAD+
SIRT3
biochemistry
cardiovascular disease
chemical biology
human
mitochondrial dna
mouse
nicotinamide riboside
Journal
eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614
Informations de publication
Date de publication:
03 08 2021
03 08 2021
Historique:
received:
09
06
2020
accepted:
06
07
2021
entrez:
3
8
2021
pubmed:
4
8
2021
medline:
24
9
2021
Statut:
epublish
Résumé
Poly(ADP-ribose) polymerase (PARP) enzymes initiate (mt)DNA repair mechanisms and use nicotinamide adenine dinucleotide (NAD
Identifiants
pubmed: 34343089
doi: 10.7554/eLife.59828
pii: 59828
pmc: PMC8331182
doi:
pii:
Substances chimiques
DNA, Mitochondrial
0
Pyridinium Compounds
0
nicotinamide-beta-riboside
0I8H2M0L7N
NAD
0U46U6E8UK
Niacinamide
25X51I8RD4
Sirtuins
EC 3.5.1.-
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2021, Lauritzen et al.
Déclaration de conflit d'intérêts
KL, MO, MA, KY, JR, LB, QE, LS, MZ, HA, BH, PA, AY No competing interests declared
Références
Semin Cell Dev Biol. 2017 Mar;63:135-143
pubmed: 28013023
Cell Metab. 2013 Aug 6;18(2):239-50
pubmed: 23931755
Methods Mol Biol. 2013;1077:203-15
pubmed: 24014409
Nat Rev Genet. 2008 Aug;9(8):619-31
pubmed: 18626472
Cardiovasc Toxicol. 2007;7(2):108-13
pubmed: 17652814
Circulation. 2018 May 22;137(21):2256-2273
pubmed: 29217642
Nat Commun. 2016 Oct 10;7:12948
pubmed: 27721479
Am J Physiol Heart Circ Physiol. 2013 Aug 15;305(4):H459-76
pubmed: 23748424
Science. 2015 Dec 4;350(6265):1208-13
pubmed: 26785480
Exp Gerontol. 2010 Aug;45(7-8):478-88
pubmed: 20096766
Mol Cell. 2005 Mar 18;17(6):855-68
pubmed: 15780941
Science. 2016 Jun 17;352(6292):1436-43
pubmed: 27127236
Nat Protoc. 2008;3(1):144-52
pubmed: 18193031
J Biol Chem. 2009 Nov 13;284(46):31616-24
pubmed: 19762472
Nat Rev Mol Cell Biol. 2019 May;20(5):267-284
pubmed: 30626975
Eur Heart J. 2009 Aug;30(15):1853-62
pubmed: 19468012
Am J Physiol Heart Circ Physiol. 2015 Aug 1;309(3):H434-49
pubmed: 26055793
J Appl Physiol (1985). 2005 Feb;98(2):680-9
pubmed: 15475595
J Mol Med (Berl). 2010 Oct;88(10):993-1001
pubmed: 20725711
EMBO J. 2020 Jul 15;39(14):e104105
pubmed: 32567732
Hepatology. 2016 Apr;63(4):1190-204
pubmed: 26404765
Neurobiol Aging. 2013 Jun;34(6):1581-8
pubmed: 23312803
EMBO Rep. 2011 Jun;12(6):534-41
pubmed: 21566644
Toxicol In Vitro. 2018 Oct;52:203-213
pubmed: 29913208
Mol Cell Biol. 2014 Mar;34(5):807-19
pubmed: 24344202
Mol Cancer Ther. 2011 Dec;10(12):2320-9
pubmed: 21926192
Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2604-2609
pubmed: 28143930
Cell Death Dis. 2013 Jul 18;4:e731
pubmed: 23868064
Antioxid Redox Signal. 2019 Jan 10;30(2):251-294
pubmed: 29634344
Cell Rep. 2019 Feb 5;26(6):1557-1572.e8
pubmed: 30726738
Int Neurourol J. 2019 Feb;23(Suppl 1):S5-10
pubmed: 30832462
Mol Cell Biol. 2010 Mar;30(6):1357-67
pubmed: 20065039
J Pharmacol Exp Ther. 2002 Mar;300(3):862-7
pubmed: 11861791
Cell. 2007 Sep 21;130(6):1095-107
pubmed: 17889652
Nat Commun. 2015 Feb 17;6:6259
pubmed: 25687472