MICU1 opens the gates to cold-induced death.


Journal

Cell calcium
ISSN: 1532-1991
Titre abrégé: Cell Calcium
Pays: Netherlands
ID NLM: 8006226

Informations de publication

Date de publication:
09 2021
Historique:
received: 29 06 2021
revised: 22 07 2021
accepted: 23 07 2021
pubmed: 4 8 2021
medline: 9 9 2021
entrez: 3 8 2021
Statut: ppublish

Résumé

Nakamura et al. recently discovered that the mitochondrial calcium uniporter gatekeeper, MICU1, is required for cold-induced ferroptotic cell death by modulating mitochondrial membrane potential. This function appears to be independent of its Ca

Identifiants

pubmed: 34343855
pii: S0143-4160(21)00105-6
doi: 10.1016/j.ceca.2021.102451
pii:
doi:

Substances chimiques

Calcium-Binding Proteins 0
Cation Transport Proteins 0
Mitochondrial Membrane Transport Proteins 0
Calcium SY7Q814VUP

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

102451

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Felicia Dietsche (F)

Institute of Molecular Medicine, University Medical Center Mainz, Germany.

Li Zhang (L)

Institute of Molecular Medicine, University Medical Center Mainz, Germany.

John W Elrod (JW)

Center for Translational Medicine, Lewis Katz School of Medicine at Temple University. 3500 N. Broad St., Philadelphia, PA 19140, United States. Electronic address: elrod@temple.edu.

Axel Methner (A)

Institute of Molecular Medicine, University Medical Center Mainz, Germany. Electronic address: axel.methner@gmail.com.

Articles similaires

Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis.

Spencer D Shelton, Sara House, Luiza Martins Nascentes Melo et al.
1.00
DNA, Mitochondrial Humans Melanoma Mutation Neoplasm Metastasis
Psoriasis Humans Magnesium Zinc Trace Elements

A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.

Lisa Demoen, Filip Matthijssens, Lindy Reunes et al.
1.00
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Animals Mice Humans Cell Line, Tumor
Adenosine Triphosphate Adenosine Diphosphate Mitochondrial ADP, ATP Translocases Binding Sites Mitochondria

Classifications MeSH