The Association of Smoking and Alcohol Abuse on Anxiety and Depression in Patients With Recurrent Acute or Chronic Pancreatitis Undergoing Total Pancreatectomy and Islet Autotransplantation: A Report From the Prospective Observational Study of TPIAT Cohort.

Acute Disease Adult Alcoholism / complications Anxiety / diagnosis Cohort Studies Depression / diagnosis Female Humans Islets of Langerhans Transplantation / methods Logistic Models Male Middle Aged Pancreatectomy / methods Pancreatitis / surgery Pancreatitis, Chronic / surgery Recurrence Risk Factors Smoking / adverse effects Transplantation, Autologous

Journal

Pancreas

ISSN: 1536-4828

Titre abrégé: Pancreas

Pays: United States

ID NLM: 8608542

Informations de publication

Date de publication:
01 07 2021

Historique:

pubmed: 5 8 2021

medline: 8 2 2022

entrez: 4 8 2021

Statut: ppublish

Résumé

Smoking and alcohol use are risk factors for acute and chronic pancreatitis, and their role on anxiety, depression, and opioid use in patients who undergo total pancreatectomy and islet autotransplantation (TPIAT) is unknown. We included adults enrolled in the Prospective Observational Study of TPIAT (POST). Measured variables included smoking (never, former, current) and alcohol abuse or dependency history (yes vs no). Using univariable and multivariable analyses, we investigated the association of smoking and alcohol dependency history with anxiety and depression, opioid use, and postsurgical outcomes. Of 195 adults studied, 25 were current smokers and 77 former smokers, whereas 18 had a history of alcohol dependency (of whom 10 were current smokers). A diagnosis of anxiety was associated with current smoking (P = 0.005), and depression was associated with history of alcohol abuse/dependency (P = 0.0001). However, active symptoms of anxiety and depression at the time of TPIAT were not associated with smoking or alcohol status. Opioid use in the past 14 days was associated with being a former smoker (P = 0.005). Active smoking and alcohol abuse history were associated with a diagnosis of anxiety and depression, respectively; however, at the time of TPIAT, symptom scores suggested that they were being addressed.

Identifiants

DOI: 10.1097/MPA.0000000000001850 PMID: 34347725 PMC: PMC8373657

pubmed: 34347725

doi: 10.1097/MPA.0000000000001850

pii: 00006676-202107000-00012

pmc: PMC8373657

mid: NIHMS1715184

doi:

Types de publication

Journal Article Observational Study Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

Pagination

852-858

Subventions

Organisme : NIDDK NIH HHS

ID : R01 DK109124

Pays : United States

Informations de copyright

Déclaration de conflit d'intérêts

L.F.F. is a consultant for Medtronic and Abbvie and a speaker for Nestle. S.C. did not declare conflict of interest related to the article. The remaining authors declare no conflict of interest.

Références

Singhvi A, Yadav D. Myths and realities about alcohol and smoking in chronic pancreatitis. Curr Opin Gastroenterol . 2018;34:355–361.

Irving HM, Samokhvalov AV, Rehm J. Alcohol as a risk factor for pancreatitis. A systematic review and meta-analysis. JOP . 2009;10:387–392.

Machicado JD, Amann ST, Anderson MA, et al. Quality of life in chronic pancreatitis is determined by constant pain, disability/unemployment, current smoking and associated co-morbidities. Am J Gastroenterol . 2017;112:633–642.

Tjora E, Dimcevski G, Haas SL, et al. Patient reported exposure to smoking and alcohol abuse are associated with pain and other complications in patients with chronic pancreatitis. Pancreatology . 2020;20:844–851.

Bellin MD, Gelrud A, Arreaza-Rubin G, et al. Total pancreatectomy with islet autotransplantation: summary of an NIDDK workshop. Ann Surg . 2015;261:21–29.

Sutherland DE, Gruessner AC, Carlson AM, et al. Islet autotransplant outcomes after total pancreatectomy: a contrast to islet allograft outcomes. Transplantation . 2008;86:1799–1802.

Blondet JJ, Carlson AM, Kobayashi T, et al. The role of total pancreatectomy and islet autotransplantation for chronic pancreatitis. Surg Clin North Am . 2007;87:1477–1501.

Walsh RM, Saavedra JR, Lentz G, et al. Improved quality of life following total pancreatectomy and auto-islet transplantation for chronic pancreatitis. J Gastrointest Surg . 2012;16:1469–1477.

Institute of Medicine. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research . Washington, DC: The National Academies Press; 2011.

Brennan PL, Schutte KK, Moos RH. Pain and use of alcohol to manage pain: prevalence and 3-year outcomes among older problem and non-problem drinkers. Addiction . 2005;100:777–786.

Gureje O, Von Korff M, Kola L, et al. The relation between multiple pains and mental disorders: results from the World Mental Health Surveys. Pain . 2008;135:82–91.

Hales CM, Martin CB, Gu Q. Prevalence of prescription pain medication use among adults: United States, 2015-2018. NCHS Data Brief . June 2020. Available at: https://www.cdc.gov/nchs/data/databriefs/db369-h.pdf . Accessed July 21, 2020.

Zale EL, Maisto SA, Ditre JW. Anxiety and depression in bidirectional relations between pain and smoking: implications for smoking cessation. Behav Modif . 2016;40:7–28.

O'Brien T, Christrup LL, Drewes AM, et al. European Pain Federation position paper on appropriate opioid use in chronic pain management. Eur J Pain . 2017;21:3–19.

Drossman D, Szigethy E. The narcotic bowel syndrome: a recent update. Am J Gastroenterol Suppl . 2014;2:22–30.

Højsted J, Sjøgren P. Addiction to opioids in chronic pain patients: a literature review. Eur J Pain . 2007;11:490–518.

Ditre JW, Brandon TH, Zale EL, et al. Pain, nicotine, and smoking: research findings and mechanistic considerations. Psychol Bull . 2011;137:1065–1093.

Ditre JW, Zale EL, LaRowe LR. A reciprocal model of pain and substance use: transdiagnostic considerations, clinical implications, and future directions. Annu Rev Clin Psychol . 2019;15:503–528.

Fluharty M, Taylor AE, Grabski M, et al. The association of cigarette smoking with depression and anxiety: a systematic review. Nicotine Tob Res . 2017;19:3–13.

Hooten MW, Shi Y, Gazelka HM, et al. The effects of depression and smoking on pain severity and opioid use in patients with chronic pain. Pain . 2011;152:223–229.

Morgan KA, Lancaster WP, Owczarski SM, et al. Patient selection for total pancreatectomy with islet autotransplantation in the surgical management of chronic pancreatitis. J Am Coll Surg . 2018;226:446–451.

Bellin MD, Abu-El-Haija M, Morgan K, et al. A multicenter study of total pancreatectomy with islet autotransplantation (TPIAT): POST (Prospective Observational Study of TPIAT). Pancreatology . 2018;18:286–290.

Patient-Reported Outcomes Measurement Information System (PROMIS). Available at: https://www.healthmeasures.net . Accessed September 30, 2020.

R Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing. Updated July 2021. Available at: https://www.R-project.org/ . Accessed May 19, 2020.

Singh VK, Yadav D, Garg PK. Diagnosis and management of chronic pancreatitis a review. JAMA . 2019;322:2422–2434.

Yadav D, Whitcomb DC. The role of alcohol and smoking in pancreatitis. Nat Rev Gastroenterol Hepatol . 2010;7:131–145.

Han S, Patel B, Min M, et al. Quality of life comparison between smokers and non-smokers with chronic pancreatitis. Pancreatology . 2018;18:269–274.

Bellin MD, Kerdsirichairat T, Beilman GJ, et al. Total pancreatectomy with islet autotransplantation improves quality of life in patients with refractory recurrent acute pancreatitis. Clin Gastroenterol Hepatol . 2016;14:1317–1323.

Garcea G, Weaver J, Phillips J, et al. Total pancreatectomy with and without islet cell transplantation for chronic pancreatitis: a series of 85 consecutive patients. Pancreas . 2009;38:1–7.

Morgan K, Owczarski SM, Borckardt J, et al. Pain control and quality of life after pancreatectomy with islet autotransplantation for chronic pancreatitis. J Gastrointest Surg . 2012;16:129–133; discussion 133-134.

Chinnakotla S, Beilman GJ, Dunn TB, et al. Factors predicting outcomes after a total pancreatectomy and islet autotransplantation lessons learned from over 500 cases. Ann Surg . 2015;262:610–622.

Solomina J, Gołębiewska J, Kijek MR, et al. Pain control, glucose control, and quality of life in patients with chronic pancreatitis after total pancreatectomy with islet autotransplantation: a preliminary report. Transplant Proc . 2017;49:2333–2339.

Takita M, Lara LF, Naziruddin B, et al. Effect of the duration of chronic pancreatitis on pancreas islet yield and metabolic outcome following islet autotransplantation. J Gastrointest Surg . 2015;19:1236–1246.

Drewes AM, Krarup AL, Detlefsen S, et al. Pain in chronic pancreatitis: the role of neuropathic pain mechanisms. Gut . 2008;57:1616–1627.

Smit T, Peraza N, Garey L, et al. Pain-related anxiety and smoking processes: the explanatory role of dysphoria. Addict Behav . 2019;88:15–22.

Wang TW, Asman K, Gentzke AS, et al. Tobacco product use among adults—United States, 2017. MMWR Morb Mortal Wkly Rep . 2018;67:1225–1232.

Center for Disease Control and Prevention Smoking and Tobacco Use. [CDC Website] 2018. Available at: https://www.cdc.gov/tobacco/data_statistics/ . Accessed July 21, 2020.

Center for Disease Control and Prevention Alcohol Use. [CDC Website] 2018. Available at: https://www.cdc.gov/nchs/hus/index.htm . Accessed July 21, 2020.

Taylor G, McNeill A, Girling A, et al. Change in mental health after smoking cessation: systematic review and meta-analysis. BMJ . 2014;348:g1151.

Han S, Kheder J, Bocelli L, et al. Smoking cessation in a chronic pancreatitis population. Pancreas . 2016;45:1303–1308.

Bellin MD, Balamurugan AN, Pruett TL, et al. No islets left behind: islet autotransplantation for surgery-induced diabetes. Curr Diab Rep . 2012;12:580–586.

Kasper S. Anxiety disorders: under-diagnosed and insufficiently treated. Int J Psychiatry Clin Pract . 2006;10 Suppl 1:S3–S9.

Andrews B, Hejdenberg J, Wilding J. Student anxiety and depression: comparison of questionnaire and interview assessments. J Affect Disord . 2006;95:29–34.

Rose M, Devine J. Assessment of patient-reported symptoms of anxiety. Dialogues Clin Neurosci . 2014;16:197–211.

Rotenstein LS, Ramos MA, Torre M, et al. Prevalence of depression, depressive symptoms, and suicidal ideation among medical students: a systematic review and meta-analysis. JAMA . 2016;316:2214–2236.

Steer RA, Kumar G, Pinninti NR, et al. Severity and internal consistency of self-reported anxiety in psychotic outpatients. Psychol Rep . 2003;93:1233–1238.

Sanchez-Villegas A, Schlatter J, Ortuno F, et al. Validity of a self-reported diagnosis of depression among participants in a cohort study using the Structured Clinical Interview for DSM-IV (SCID-I). BMC Psychiatry . 2008;8:43.

van der Steen Y, Myin-Germeys I, van Nierop M, et al. ‘False-positive’ self-reported psychotic experiences in the general population: an investigation of outcome, predictive factors and clinical relevance. Epidemiol Psychiatr Sci . 2019;28:532–543.