Mesenchymal Stem Cells: From Regeneration to Drug Delivery Systems.


Journal

Critical reviews in therapeutic drug carrier systems
ISSN: 2162-660X
Titre abrégé: Crit Rev Ther Drug Carrier Syst
Pays: United States
ID NLM: 8511159

Informations de publication

Date de publication:
2021
Historique:
entrez: 4 8 2021
pubmed: 5 8 2021
medline: 26 10 2021
Statut: ppublish

Résumé

Targeting drug delivery has been a focus of researchers in recent years for cancer and other diseases. Many approaches such as liposomes, exosomes, nanoparticles (magnetic), encapsulation etc. have been developed and investigated for their clinical applications. But disadvantages linked to these therapies limit them to be used in clinical settings. Cell based drug delivery systems has emerged as an alternative for these therapies. Among cell types, mesenchymal stem cells (MSCs) proved to a potential cell type for research due to its many characteristics including low immunogenicity, chemotaxis and homing to tumor sites which are considered mandatory for drug delivery. This chapter focuses on the challenges and opportunities in using MSCs as therapeutic carrier of drugs in different ailments.

Identifiants

pubmed: 34348018
pii: 4ae70f000b405f97,41de53e70329c19a
doi: 10.1615/CritRevTherDrugCarrierSyst.2021033916
doi:

Substances chimiques

Liposomes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

33-73

Auteurs

Zeeshan Shokat (Z)

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad (GCUF), Allama Iqbal Road, Faisalabad-38000, Pakistan.

Abdaal Ali (A)

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad (GCUF), Allama Iqbal Road, Faisalabad-38000, Pakistan.

Uzair Ahmed (U)

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad (GCUF), Allama Iqbal Road, Faisalabad-38000, Pakistan; Department of Physiology and Cell Biology, University of Health Sciences, Lahore, Pakistan.

Muhammad Rizwan Javed (MR)

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad (GCUF), Allama Iqbal Road, Faisalabad-38000, Pakistan.

Muhammad Qasim (M)

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad (GCUF), Allama Iqbal Road, Faisalabad-38000, Pakistan.

Muhammad Tariq (M)

Department of Biotechnology, Mirpur University of Science and Technology, Mirpur, Azad Jammu and Kashmir, Pakistan.

Muhammad Rauf Ahmed (MR)

Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.

Muhammad Shareef Masoud (MS)

Department of Bioinformatics and Biotechnology, Government College University, Faisalabad (GCUF), Allama Iqbal Road, Faisalabad-38000, Pakistan.

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Classifications MeSH