Mesenchymal Stem Cells: From Regeneration to Drug Delivery Systems.
Journal
Critical reviews in therapeutic drug carrier systems
ISSN: 2162-660X
Titre abrégé: Crit Rev Ther Drug Carrier Syst
Pays: United States
ID NLM: 8511159
Informations de publication
Date de publication:
2021
2021
Historique:
entrez:
4
8
2021
pubmed:
5
8
2021
medline:
26
10
2021
Statut:
ppublish
Résumé
Targeting drug delivery has been a focus of researchers in recent years for cancer and other diseases. Many approaches such as liposomes, exosomes, nanoparticles (magnetic), encapsulation etc. have been developed and investigated for their clinical applications. But disadvantages linked to these therapies limit them to be used in clinical settings. Cell based drug delivery systems has emerged as an alternative for these therapies. Among cell types, mesenchymal stem cells (MSCs) proved to a potential cell type for research due to its many characteristics including low immunogenicity, chemotaxis and homing to tumor sites which are considered mandatory for drug delivery. This chapter focuses on the challenges and opportunities in using MSCs as therapeutic carrier of drugs in different ailments.
Identifiants
pubmed: 34348018
pii: 4ae70f000b405f97,41de53e70329c19a
doi: 10.1615/CritRevTherDrugCarrierSyst.2021033916
doi:
Substances chimiques
Liposomes
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM