Adipocyte NR1D1 dictates adipose tissue expansion during obesity.


Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
05 08 2021
Historique:
received: 22 09 2020
accepted: 30 07 2021
pubmed: 6 8 2021
medline: 9 10 2021
entrez: 5 8 2021
Statut: epublish

Résumé

The circadian clock component NR1D1 (REVERBα) is considered a dominant regulator of lipid metabolism, with global

Identifiants

pubmed: 34350828
doi: 10.7554/eLife.63324
pii: 63324
pmc: PMC8360653
doi:
pii:

Substances chimiques

Nr1d1 protein, mouse 0
Nuclear Receptor Subfamily 1, Group D, Member 1 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Medical Research Council
ID : MR/P023576/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/I018654/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 107851/Z/15/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P00279X/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/M008908/1
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 107849/Z/15/Z
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N021479/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P023576/2
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P011853/1
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom

Informations de copyright

© 2021, Hunter et al.

Déclaration de conflit d'intérêts

AH, CP, NB, RN, MG, AA, PD, TC, PC, LH, AL, RU, MI, DR, DB No competing interests declared, JB J-N.B. is an employee of Qiagen.

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Auteurs

Ann Louise Hunter (AL)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Charlotte E Pelekanou (CE)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Nichola J Barron (NJ)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Rebecca C Northeast (RC)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Magdalena Grudzien (M)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Antony D Adamson (AD)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Polly Downton (P)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Thomas Cornfield (T)

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom.

Peter S Cunningham (PS)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Jean-Noel Billaud (JN)

Digital Insights, Qiagen, Redwood City, United States.

Leanne Hodson (L)

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom.

Andrew Si Loudon (AS)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Richard D Unwin (RD)

Stoller Biomarker Discovery Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

Mudassar Iqbal (M)

Division of Informatics, Imaging and Data Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

David W Ray (DW)

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, and NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom.

David A Bechtold (DA)

Centre for Biological Timing, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.

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Classifications MeSH