Pharmacokinetics and Bioequivalence Evaluation of 2 Formulations of Tenofovir Alafenamide.
bioequivalence
pharmacokinetics
tenofovir alafenamide
Journal
Clinical pharmacology in drug development
ISSN: 2160-7648
Titre abrégé: Clin Pharmacol Drug Dev
Pays: United States
ID NLM: 101572899
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
12
03
2021
accepted:
10
05
2021
pubmed:
6
8
2021
medline:
5
4
2022
entrez:
5
8
2021
Statut:
ppublish
Résumé
The study was conducted to compare the pharmacokinetics and safety profiles of 2 brands of tenofovir alafenamide (TAF) fumarate tablets. This research was a 2-preparation, 2-sequence, 4-period crossover, completely replicated study in 68 healthy Chinese subjects under fasting and fed conditions. The mean values of the area under the concentration-time curve from time 0 to the last time point with blood sample collection (AUC
Substances chimiques
Tablets
0
Tenofovir
99YXE507IL
tenofovir alafenamide
EL9943AG5J
Alanine
OF5P57N2ZX
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1519-1527Informations de copyright
© 2021, The American College of Clinical Pharmacology.
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