Total pancreatectomy and pancreatic fistula: friend or foe?


Journal

Updates in surgery
ISSN: 2038-3312
Titre abrégé: Updates Surg
Pays: Italy
ID NLM: 101539818

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 29 05 2021
accepted: 12 07 2021
pubmed: 8 8 2021
medline: 16 10 2021
entrez: 7 8 2021
Statut: ppublish

Résumé

Postoperative pancreatic fistula (POPF) still represents the major driver of surgical morbidity after pancreaticoduodenectomy. The purpose of this narrative review was to critically analyze current evidence supporting the use of total pancreatectomy (TP) to prevent the development of POPF in patients with high-risk pancreas, and to explore the role of completion total pancreatectomy (CP) in the management of severe POPF. Considering the encouraging perioperative outcomes, TP may represent a promising tool to avoid the morbidity related to an extremely high-risk pancreatic anastomosis in selected patients. Surgical management of severe POPF is only required in few critical scenarios. In this context, even if anecdotal, CP might play a role as last resort in expert hands.

Identifiants

pubmed: 34363601
doi: 10.1007/s13304-021-01130-3
pii: 10.1007/s13304-021-01130-3
pmc: PMC8397676
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1231-1236

Informations de copyright

© 2021. The Author(s).

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Auteurs

Roberto Salvia (R)

Department of Surgery, Dentistry, Gynecology and Pediatrics (DSCOMI), Unit of General and Pancreatic Surgery, University of Verona, G.B. Rossi Hospital, P.Le Scuro 10, 37134, Verona, Italy. roberto.salvia@univr.it.

Gabriella Lionetto (G)

Department of Surgery, Dentistry, Gynecology and Pediatrics (DSCOMI), Unit of General and Pancreatic Surgery, University of Verona, G.B. Rossi Hospital, P.Le Scuro 10, 37134, Verona, Italy.

Giampaolo Perri (G)

Department of Surgery, Dentistry, Gynecology and Pediatrics (DSCOMI), Unit of General and Pancreatic Surgery, University of Verona, G.B. Rossi Hospital, P.Le Scuro 10, 37134, Verona, Italy.

Giuseppe Malleo (G)

Department of Surgery, Dentistry, Gynecology and Pediatrics (DSCOMI), Unit of General and Pancreatic Surgery, University of Verona, G.B. Rossi Hospital, P.Le Scuro 10, 37134, Verona, Italy.

Giovanni Marchegiani (G)

Department of Surgery, Dentistry, Gynecology and Pediatrics (DSCOMI), Unit of General and Pancreatic Surgery, University of Verona, G.B. Rossi Hospital, P.Le Scuro 10, 37134, Verona, Italy.

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