Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland-type lung adenocarcinoma diagnosed due to esophageal stricture: A case report.
Adenocarcinoma of Lung
/ drug therapy
Aged
Antibodies, Monoclonal, Humanized
/ therapeutic use
Antineoplastic Agents
/ therapeutic use
Antineoplastic Agents, Immunological
/ therapeutic use
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Carboplatin
/ therapeutic use
Deglutition Disorders
Esophageal Stenosis
Fatal Outcome
Female
Humans
Lung Neoplasms
/ drug therapy
Pemetrexed
/ therapeutic use
Salivary Glands
/ pathology
carboplatin
case report
pembrolizumab
pemetrexed
primary salivary gland-type tumor of the lung
Journal
Thoracic cancer
ISSN: 1759-7714
Titre abrégé: Thorac Cancer
Pays: Singapore
ID NLM: 101531441
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
revised:
22
07
2021
received:
01
07
2021
accepted:
23
07
2021
pubmed:
10
8
2021
medline:
29
1
2022
entrez:
9
8
2021
Statut:
ppublish
Résumé
Primary salivary gland-type tumors of the lung are rare, accounting for <1% of all lung tumors. There are few reports on chemotherapy for the treatment of primary salivary gland-type tumors of the lung. The patient in this report was a 71-year-old woman who presented with a chief complaint of dysphagia. Upper gastrointestinal endoscopy revealed an esophageal stricture, but biopsy showed no malignancy. Chest computed tomography (CT) showed carcinomatous lymphangiomatosis and a nodule in the right lung. Bronchoscopy showed a rough mucous membrane of the central bronchi, while biopsy showed adenocarcinoma. The patient was diagnosed with bronchogenic adenocarcinoma and received carboplatin, pemetrexed, and pembrolizumab, which alleviated the esophageal stricture and cancerous lymphangiopathy. However, the adenocarcinoma progressed, and she subsequently received several rounds of chemotherapy. One year after diagnosis, the patient died, and pathological autopsy revealed primary salivary gland-type tumors of the lung.
Identifiants
pubmed: 34369074
doi: 10.1111/1759-7714.14100
pmc: PMC8447908
doi:
Substances chimiques
Antibodies, Monoclonal, Humanized
0
Antineoplastic Agents
0
Antineoplastic Agents, Immunological
0
Pemetrexed
04Q9AIZ7NO
Carboplatin
BG3F62OND5
pembrolizumab
DPT0O3T46P
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
2513-2516Informations de copyright
© 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd.
Références
Genome Res. 2012 Nov;22(11):2109-19
pubmed: 22975805
Diagn Pathol. 2020 Jun 6;15(1):71
pubmed: 32505185
Cancer. 2007 Nov 15;110(10):2253-9
pubmed: 17918258
Adv Anat Pathol. 2016 Jan;23(1):13-23
pubmed: 26645458
J Thorac Oncol. 2015 Sep;10(9):1243-1260
pubmed: 26291008
Lung Cancer. 2018 Dec;126:174-181
pubmed: 30527184
Lung Cancer. 2020 Aug;146:58-65
pubmed: 32512274
J Thorac Oncol. 2013 Dec;8(12):1578-84
pubmed: 24389442
Thorac Cancer. 2021 Sep;12(18):2513-2516
pubmed: 34369074
Future Sci OA. 2019 May 03;5(5):FSO394
pubmed: 31205749