Acute Administration of Bioavailable Curcumin Alongside Ferrous Sulphate Supplements Does Not Impair Iron Absorption in Healthy Adults in a Randomised Trial.
Absorption, Physiological
/ drug effects
Administration, Oral
Adult
Biological Availability
Curcumin
/ administration & dosage
Dietary Supplements
Double-Blind Method
Female
Ferritins
/ blood
Ferrous Compounds
/ administration & dosage
Healthy Volunteers
Hemoglobins
/ analysis
Humans
Iron
/ blood
Iron-Binding Proteins
/ blood
Male
Transferrin
/ analysis
antioxidant
curcumin
ferrous sulphate
iron
nutrition
supplementation
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
03 Jul 2021
03 Jul 2021
Historique:
received:
28
05
2021
revised:
17
06
2021
accepted:
30
06
2021
entrez:
10
8
2021
pubmed:
11
8
2021
medline:
10
9
2021
Statut:
epublish
Résumé
Ferrous sulphate (FS) is a cost effective, readily available iron supplement for iron deficiency (ID). The pro-oxidant effect of oral ferrous iron is known to induce inflammation, causing gastric side-effects and resulting in poor compliance. Curcumin is a potent antioxidant and has also been shown to exhibit iron chelation in-vitro, although it is not established whether these effects are retained in-vivo. The aim of this study was therefore to assess the influence of a formulated bioavailable form of curcumin (HydroCurc
Identifiants
pubmed: 34371810
pii: nu13072300
doi: 10.3390/nu13072300
pmc: PMC8308323
pii:
doi:
Substances chimiques
Ferrous Compounds
0
Hemoglobins
0
Iron-Binding Proteins
0
Transferrin
0
ferrous sulfate
39R4TAN1VT
Ferritins
9007-73-2
Iron
E1UOL152H7
Curcumin
IT942ZTH98
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Gencor Pacific Limited
ID : UT722720
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