The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
09 08 2021
09 08 2021
Historique:
received:
27
12
2020
accepted:
26
07
2021
entrez:
10
8
2021
pubmed:
11
8
2021
medline:
12
11
2021
Statut:
epublish
Résumé
Few studies have investigated the relationship between blood type and trauma outcomes according to the type of injury. We conducted a retrospective multicenter observational study in twelve emergency hospitals in Japan. Patients with isolated severe abdominal injury (abbreviated injury scale for the abdomen ≥ 3 and that for other organs < 3) that occurred between 2008 and 2018 were divided into four groups according to blood type. The association between blood type and mortality, ventilator-free days (VFD), and total transfusion volume were evaluated using univariate and multivariate regression models. A total of 920 patients were included, and were divided based on their blood type: O, 288 (31%); A, 345 (38%); B, 186 (20%); and AB, 101 (11%). Patients with type O had a higher in-hospital mortality rate than those of other blood types (22% vs. 13%, p < 0.001). This association was observed in multivariate analysis (adjusted odds ratio [95% confidence interval] = 1.48 [1.25-2.26], p = 0.012). Furthermore, type O was associated with significantly higher cause-specific mortalities, fewer VFD, and larger transfusion volumes. Blood type O was associated with significantly higher mortality and larger transfusion volumes in patients with isolated severe abdominal trauma.
Identifiants
pubmed: 34373499
doi: 10.1038/s41598-021-95443-3
pii: 10.1038/s41598-021-95443-3
pmc: PMC8352974
doi:
Substances chimiques
Blood Group Antigens
0
Types de publication
Journal Article
Multicenter Study
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
16147Informations de copyright
© 2021. The Author(s).
Références
Thromb Haemost. 2007 Apr;97(4):534-41
pubmed: 17393014
APMIS Suppl. 1992;27:28-38
pubmed: 1520528
Shock. 2020 Aug;54(2):205-208
pubmed: 32108729
Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1958-67
pubmed: 19729612
J Burn Care Res. 2020 Sep 23;41(5):1111-1117
pubmed: 32249907
J Biol Chem. 1995 Mar 3;270(9):4640-9
pubmed: 7876235
J Trauma. 1989 May;29(5):623-9
pubmed: 2657085
Hum Mol Genet. 2010 May 1;19(9):1863-72
pubmed: 20167578
Semin Thromb Hemost. 2012 Jul;38(5):535-48
pubmed: 22740183
Br Med J. 1953 Apr 11;1(4814):799-801
pubmed: 13032504
Transfusion. 2006 Oct;46(10):1836-44
pubmed: 17002642
Diagnostics (Basel). 2020 Oct 15;10(10):
pubmed: 33076323
J Biol Chem. 2003 Jun 13;278(24):21869-77
pubmed: 12672794
Chest. 2014 Apr;145(4):753-761
pubmed: 24385226
Arch Surg. 2005 Aug;140(8):767-72
pubmed: 16103287
JAMA. 1971 Jan 11;215(2):277-80
pubmed: 5107365
Crit Care Med. 2002 Aug;30(8):1772-7
pubmed: 12163791
Semin Thromb Hemost. 2013 Feb;39(1):72-82
pubmed: 23299820
Cancer Epidemiol. 2015 Apr;39(2):150-6
pubmed: 25600007
Blood. 1987 Jun;69(6):1691-5
pubmed: 3495304
Expert Opin Ther Targets. 2007 Nov;11(11):1473-91
pubmed: 18028011
Am J Hum Genet. 1981 May;33(3):421-31
pubmed: 7246545
Transfus Med. 2001 Aug;11(4):343-51
pubmed: 11532189
J Trauma. 2008 Feb;64(2 Suppl):S21-6; discussion S26-7
pubmed: 18376168
Haematologica. 2007 Feb;92(2):236-9
pubmed: 17296574
Orthop Rev (Pavia). 2019 Dec 02;11(4):8214
pubmed: 31897279
Lancet. 2014 Oct 18;384(9952):1455-65
pubmed: 25390327
PLoS One. 2018 Oct 25;13(10):e0206403
pubmed: 30359446
J Thromb Haemost. 2008 Jan;6(1):62-9
pubmed: 17973651
Crit Care. 2018 May 2;22(1):100
pubmed: 29716619
Transfus Sci. 1997 Dec;18(4):613-20
pubmed: 10178687
Clin J Am Soc Nephrol. 2015 Nov 6;10(11):1911-20
pubmed: 26342043