Prognostic Value of Peak Oxygen Uptake in Patients Supported With Left Ventricular Assist Devices (PRO-VAD).


Journal

JACC. Heart failure
ISSN: 2213-1787
Titre abrégé: JACC Heart Fail
Pays: United States
ID NLM: 101598241

Informations de publication

Date de publication:
10 2021
Historique:
received: 05 04 2021
revised: 14 05 2021
accepted: 18 05 2021
pubmed: 16 8 2021
medline: 29 10 2021
entrez: 15 8 2021
Statut: ppublish

Résumé

The purpose of this study was to examine whether peak oxygen uptake (pVO pVO We collected data for pVO Nine centers contributed data from 450 patients. Patients were 53 ± 13 years of age; 78% were male; body mass index was 25 ± 5 kg/m Even after LVAD implantation, pVO

Sections du résumé

OBJECTIVES
The purpose of this study was to examine whether peak oxygen uptake (pVO
BACKGROUND
pVO
METHODS
We collected data for pVO
RESULTS
Nine centers contributed data from 450 patients. Patients were 53 ± 13 years of age; 78% were male; body mass index was 25 ± 5 kg/m
CONCLUSIONS
Even after LVAD implantation, pVO

Identifiants

pubmed: 34391745
pii: S2213-1779(21)00324-3
doi: 10.1016/j.jchf.2021.05.021
pii:
doi:

Substances chimiques

Oxygen S88TT14065

Banques de données

ClinicalTrials.gov
['NCT04423562']

Types de publication

Journal Article Multicenter Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

758-767

Subventions

Organisme : NHLBI NIH HHS
ID : K23 HL146889
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : ErratumIn

Informations de copyright

Copyright © 2021 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Funding Support and Author Disclosures Dr Mirza received Danish funding from Skibsreder Per Henriksen, R og hustrus Fond grant 10403/53 and Jascha Fonden grants 6186 and 7724. Dr Gustafsson is supported by research grant NNF20OC006056 from the Novo Nordisk Foundation. Dr Brahmbhatt has received travel support from Abbott, Biotronik; and has received honoraria, travel support, and research funding from Boston Scientific (all outside the submitted work). Dr Hsu has received U.S. National Institutes of Health funding (grant K23-HL146889) (all outside the submitted work). Dr MacGowan is supported by EU Horizon 2020 and United Kingdom National Institute of Health Research. Dr Jakovljevic is supported by EU Horizon 2020 Research and Innovation Programme under grant agreements 777204 and 952603. Dr Gustafsson has received personal fees from Abbott, Carmat, Pfizer, Novartis, Orion Pharma, Boehringer Ingelheim, Pharmacosmos, Amgen, Bayer, and AstraZeneca; and is a consultant for Abbott, Carmat, Pfizer, Novartis, Orion Pharma, Boehringer-Ingelheim, Pharmacosmos, Amgen, Bayer and AstraZeneca (all outside the submitted work). Dr Russell is a consultant for Medtronic and Abbott (all outside the submitted work). Dr Jorde is a consultant for Abbott (all outside the submitted work). All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Auteurs

Kiran K Mirza (KK)

Department of Cardiology, Rigshospitalet, Copenhagen, Denmark. Electronic address: RNZ440@sund.ku.dk.

Mariusz K Szymanski (MK)

Heart Lung Center Utrecht, Utrecht, the Netherlands.

Thomas Schmidt (T)

Schüchtermann-Klinik Bad Rothenfelde, Institute for Cardiovascular Research, Bad Rothenfelde, Germany, and Institute for Cardiology and Sports Medicine, German Sports University Cologne, Cologne, Germany.

Nicolaas de Jonge (N)

Heart Lung Center Utrecht, Utrecht, the Netherlands.

Darshan H Brahmbhatt (DH)

Peter Munk Cardiac Centre, Division of Cardiology, Ted Rogers Centre for Heart Research, University Health Network, University of Toronto, Toronto, Ontario, Canada; Division of Cardiology, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

Filio Billia (F)

Peter Munk Cardiac Centre, Division of Cardiology, Ted Rogers Centre for Heart Research, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Steven Hsu (S)

Advanced Heart Failure, Mechanical Circulatory Support, Transplant Cardiology, Johns Hopkins Hospital, Baltimore, Maryland, USA.

Guy A MacGowan (GA)

Department of Cardiology, Freeman Hospital and Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom; Faculty of Health and Life Sciences, Coventry University, University Hospital Coventry and Warwickshire, United Kingdom.

Djordje G Jakovljevic (DG)

Department of Cardiology, Freeman Hospital and Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom; Faculty of Health and Life Sciences, Coventry University, University Hospital Coventry and Warwickshire, United Kingdom; Department of Cardiology, Freeman Hospital and Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.

Piergiuseppe Agostoni (P)

Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milano, Italy; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milano, Milano, Italy.

Filippo Trombara (F)

Montefiore Einstein Center for Heart and Vascular Care New York, New York City, New York, USA.

Ulrich Jorde (U)

Montefiore Einstein Center for Heart and Vascular Care New York, New York City, New York, USA.

Yogita Rochlani (Y)

Montefiore Einstein Center for Heart and Vascular Care New York, New York City, New York, USA.

Katrien Vandersmissen (K)

Department of Cardiac Surgery, Katholieke Universiteit Leuven, Leuven, Belgium.

Nils Reiss (N)

Schüchtermann-Klinik Bad Rothenfelde, Institute for Cardiovascular Research, Bad Rothenfelde, Germany, and Institute for Cardiology and Sports Medicine, German Sports University Cologne, Cologne, Germany.

Stuart D Russell (SD)

Department of Cardiology, Duke University Health System, Durham, North Carolina, USA.

Bart Meyns (B)

Department of Cardiac Surgery, Katholieke Universiteit Leuven, Leuven, Belgium.

Finn Gustafsson (F)

Department of Cardiology, Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, Rigshospitalet, Copenhagen, Denmark. Electronic address: https://twitter.com/FinnGustafsson.

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