Animals Anions Organic Anion Transporters Peptides Polyphenols Rats Rosuvastatin Calcium
Organic anion-transporting polypeptide 2B1 phloretin phloridzin rosuvastatin

Journal

Xenobiotica; the fate of foreign compounds in biological systems
ISSN: 1366-5928
Titre abrégé: Xenobiotica
Pays: England
ID NLM: 1306665

Informations de publication

Date de publication:
Nov 2021
Historique:
pubmed: 17 8 2021
medline: 15 12 2021
entrez: 16 8 2021
Statut: ppublish

Résumé

Organic anion-transporting polypeptide (OATP) 2B1 plays a critical role in the intestinal absorption of substrate drugs. Apple juice reportedly interacts with OATP2B1 substrate drugs. The purpose of this study was to investigate the effect of two apple polyphenols, phloretin and phloridzin, on OATP2B1-mediated substrate transport

Identifiants

DOI: 10.1080/00498254.2021.1969480 PMID: 34396892
pubmed: 34396892
doi: 10.1080/00498254.2021.1969480
doi:

Substances chimiques

Anions 0
Organic Anion Transporters 0
Peptides 0
Polyphenols 0
Rosuvastatin Calcium 83MVU38M7Q

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1318-1325

Auteurs

Yuka Takahashi (Y)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

Katsuya Narumi (K)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
ORCID: 0000-0002-1633-7041

Takanobu Nadai (T)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

Hinata Ueda (H)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

Taiki Yamamura (T)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

Ayako Furugen (A)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

Masaki Kobayashi (M)

Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
ORCID: 0000-0003-3762-2391

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux ›
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Anions ›
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs d'anions › Transporteurs d'anions organiques ›
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides ›
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Polyphénols ›
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats ›
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrimidines › Rosuvastatine de calcium ›