Assessing the mediating role of impulsivity between methamphetamine-induced psychotic disorders and increased gambling severity in methamphetamine-dependent individuals.
Impulsivity
Mediation
Methamphetamine-induced psychotic disorders (MIPD)
Pathological gambling (PG)
Journal
European archives of psychiatry and clinical neuroscience
ISSN: 1433-8491
Titre abrégé: Eur Arch Psychiatry Clin Neurosci
Pays: Germany
ID NLM: 9103030
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
received:
12
04
2021
accepted:
11
08
2021
pubmed:
17
8
2021
medline:
23
8
2022
entrez:
16
8
2021
Statut:
ppublish
Résumé
Pathological gambling (PG) and methamphetamine-induced psychotic disorders (MIPD) both frequently occurs in methamphetamine-dependent individuals. The current study examined whether impulsivity mediated the relationship between MIPD and gambling severity. The sample consisted of 320 pathological gamblers with methamphetamine dependence (mean age 32.6 years, ranging from 15 to 64 years) voluntarily recruited from three rehabilitation centers in Hunan, China. The semistructured clinical interview of DSM-IV-TR Axis I Disorders Patient Edition was used to diagnosis the presence of MIPD and PG by registered psychiatrists. The severity of gambling symptoms was assessed using the global assessment of functioning scale, and the Barratt Impulsiveness Scale-11 provided a measure of impulsivity. Of the sample, 53.4% of participants (n = 171) met diagnostic criteria for MIPD. Individuals with a dual diagnosis of MIPD were associated with higher levels of impulsivity and greater gambling severity. Notably, support for our hypothesized mediation model was found such that impulsivity mediated the association between MIPD and gambling severity. Our findings imply that impulsivity appears to be a transdiagnostic process, which may be targeted in treatment among pathological gamblers with a dual diagnosis of MIPD to reduce gambling behaviors. Limits and future directions for research are discussed.
Identifiants
pubmed: 34398267
doi: 10.1007/s00406-021-01320-5
pii: 10.1007/s00406-021-01320-5
doi:
Substances chimiques
Methamphetamine
44RAL3456C
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1109-1117Subventions
Organisme : the National Natural Science Foundation of China
ID : 82001405
Organisme : the key program of the national natural science of china
ID : 81130020
Organisme : National Basic Research Program of China (973 Program)
ID : 2015CB553500
Informations de copyright
© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.
Références
World Drug Report (2017) United Nations Office of Drugs on Crime (UNODC). United Nations Publications, Vienna
Annual Report on Drug Control in China (2019) National Narcotic Control Commission (NNCC). Ministry of Public Security, Beijing
Lecomte T, Dumais A, Dugre JR, Potvin S (2018) The prevalence of substance-induced psychotic disorder in methamphetamine misusers: a meta-analysis. Psychiatry Res 268:189–192. https://doi.org/10.1016/j.psychres.2018.05.033
doi: 10.1016/j.psychres.2018.05.033
pubmed: 30041133
Mahoney JJ 3rd, Kalechstein AD, De La Garza R, Newton TF 2nd (2008) Presence and persistence of psychotic symptoms in cocaine- versus methamphetamine-dependent participants. Am J Addict 17(2):83–98. https://doi.org/10.1080/10550490701861201
doi: 10.1080/10550490701861201
pubmed: 18393050
pmcid: 4119877
McKetin R (2018) Methamphetamine psychosis: insights from the past. Addiction 113(8):1522–1527. https://doi.org/10.1111/add.14170
doi: 10.1111/add.14170
pubmed: 29516555
McKetin R, Leung J, Stockings E, Huo Y, Foulds J, Lappin JM et al (2019) Mental health outcomes associated with of the use of amphetamines: a systematic review and meta-analysis. EClinicalMedicine 16:81–97. https://doi.org/10.1016/j.eclinm.2019.09.014
doi: 10.1016/j.eclinm.2019.09.014
pubmed: 31832623
pmcid: 6890973
American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC
American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington, DC
Lorains FK, Cowlishaw S, Thomas SA (2011) Prevalence of comorbid disorders in problem and pathological gambling: systematic review and meta-analysis of population surveys. Addiction 106(3):490–498. https://doi.org/10.1111/j.1360-0443.2010.03300.x
doi: 10.1111/j.1360-0443.2010.03300.x
pubmed: 21210880
Ibanez A, Blanco C, Donahue E, Lesieur HR, Perez de Castro I, Fernandez-Piqueras J et al (2001) Psychiatric comorbidity in pathological gamblers seeking treatment. Am J Psychiatry 158(10):1733–1735. https://doi.org/10.1176/ajp.158.10.1733
doi: 10.1176/ajp.158.10.1733
pubmed: 11579014
Pullman RE, Potenza MN, Kraus SW (2018) Recommendations for increasing research on co-occurring serious mental illness and gambling problems. J Behav Addict 7(4):897–899. https://doi.org/10.1556/2006.7.2018.104
doi: 10.1556/2006.7.2018.104
pubmed: 30418072
pmcid: 6376370
Yakovenko I, Clark CM, Hodgins DC, Goghari VM (2016) A qualitative analysis of the effects of a comorbid disordered gambling diagnosis with schizophrenia. Schizophr Res 171(1–3):50–55. https://doi.org/10.1016/j.schres.2015.12.008
doi: 10.1016/j.schres.2015.12.008
pubmed: 26777882
Creswell KG, Wright AGC, Flory JD, Skrzynski CJ, Manuck SB (2019) Multidimensional assessment of impulsivity-related measures in relation to externalizing behaviors. Psychol Med 49(10):1678–1690. https://doi.org/10.1017/S0033291718002295
doi: 10.1017/S0033291718002295
pubmed: 30178723
de Wit H (2009) Impulsivity as a determinant and consequence of drug use: a review of underlying processes. Addict Biol 14(1):22–31. https://doi.org/10.1111/j.1369-1600.2008.00129.x
doi: 10.1111/j.1369-1600.2008.00129.x
pubmed: 18855805
Bakhshani NM (2014) Impulsivity: a predisposition toward risky behaviors. Int J High Risk Behav Addict 3(2):e20428. https://doi.org/10.5812/ijhrba.20428
doi: 10.5812/ijhrba.20428
pubmed: 25032165
pmcid: 4080475
Kozak K, Lucatch AM, Lowe DJE, Balodis IM, MacKillop J, George TP (2019) The neurobiology of impulsivity and substance use disorders: implications for treatment. Ann N Y Acad Sci 1451(1):71–91. https://doi.org/10.1111/nyas.13977
doi: 10.1111/nyas.13977
pubmed: 30291624
Ioannidis K, Hook R, Wickham K, Grant JE, Chamberlain SR (2019) Impulsivity in Gambling Disorder and problem gambling: a meta-analysis. Neuropsychopharmacology 44(8):1354–1361. https://doi.org/10.1038/s41386-019-0393-9
doi: 10.1038/s41386-019-0393-9
pubmed: 30986818
pmcid: 6588525
Kester HM, Sevy S, Yechiam E, Burdick KE, Cervellione KL, Kumra S (2006) Decision-making impairments in adolescents with early-onset schizophrenia. Schizophr Res 85(1–3):113–123. https://doi.org/10.1016/j.schres.2006.02.028
doi: 10.1016/j.schres.2006.02.028
pubmed: 16733084
Uhlmann A, Fouche JP, Lederer K, Meintjes EM, Wilson D, Stein DJ (2016) White matter microstructure and impulsivity in methamphetamine dependence with and without a history of psychosis. Hum Brain Mapp 37(6):2055–2067. https://doi.org/10.1002/hbm.23159
doi: 10.1002/hbm.23159
pubmed: 26936688
pmcid: 6867545
Moallem NR, Courtney KE, Ray LA (2018) The relationship between impulsivity and methamphetamine use severity in a community sample. Drug Alcohol Depend 187:1–7. https://doi.org/10.1016/j.drugalcdep.2018.01.034
doi: 10.1016/j.drugalcdep.2018.01.034
pubmed: 29626740
pmcid: 6410745
MacKillop J, Amlung MT, Few LR, Ray LA, Sweet LH, Munafo MR (2011) Delayed reward discounting and addictive behavior: a meta-analysis. Psychopharmacology 216(3):305–321. https://doi.org/10.1007/s00213-011-2229-0
doi: 10.1007/s00213-011-2229-0
pubmed: 21373791
pmcid: 3201846
Phillips MR, Zhang J, Shi Q, Song Z, Ding Z, Pang S et al (2009) Prevalence, treatment, and associated disability of mental disorders in four provinces in China during 2001–05: an epidemiological survey. Lancet 373(9680):2041–2053. https://doi.org/10.1016/S0140-6736(09)60660-7
doi: 10.1016/S0140-6736(09)60660-7
pubmed: 19524780
Yao S, Yang H, Zhu X, Auerbach RP, Abela JR, Pulleyblank RW et al (2007) An examination of the psychometric properties of the Chinese version of the Barratt Impulsiveness Scale, 11th version in a sample of Chinese adolescents. Percept Mot Skills 104(3 Pt 2):1169–1182. https://doi.org/10.2466/pms.104.4.1169-1182
doi: 10.2466/pms.104.4.1169-1182
pubmed: 17879649
Grant JE, Chamberlain SR (2015) Gambling disorder and its relationship with substance use disorders: implications for nosological revisions and treatment. Am J Addict 24(2):126–131. https://doi.org/10.1111/ajad.12112
doi: 10.1111/ajad.12112
pubmed: 25864600
Wu AM, Lau JT (2015) Gambling in China: socio-historical evolution and current challenges. Addiction 110(2):210–216. https://doi.org/10.1111/add.12710
doi: 10.1111/add.12710
pubmed: 25238131
Blaszczynski A, Nower L (2002) A pathways model of problem and pathological gambling. Addiction 97(5):487–499. https://doi.org/10.1046/j.1360-0443.2002.00015.x
doi: 10.1046/j.1360-0443.2002.00015.x
pubmed: 12033650
Meltzer HY, Massey BW, Horiguchi M (2012) Serotonin receptors as targets for drugs useful to treat psychosis and cognitive impairment in schizophrenia. Curr Pharm Biotechnol 13(8):1572–1586. https://doi.org/10.2174/138920112800784880
doi: 10.2174/138920112800784880
pubmed: 22283753
Potenza MN, Steinberg MA, McLaughlin SD, Wu R, Rounsaville BJ, O’Malley SS (2001) Gender-related differences in the characteristics of problem gamblers using a gambling helpline. Am J Psychiatry 158(9):1500–1505. https://doi.org/10.1176/appi.ajp.158.9.1500
doi: 10.1176/appi.ajp.158.9.1500
pubmed: 11532738
Desai RA, Potenza MN (2009) A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder. J Clin Psychiatry 70(9):1250–1257. https://doi.org/10.4088/JCP.08m04359
doi: 10.4088/JCP.08m04359
pubmed: 19538900
pmcid: 3695825
Potenza MN, Chambers RA (2001) Schizophrenia and pathological gambling. Am J Psychiatry 158(3):497–498. https://doi.org/10.1176/appi.ajp.158.3.497-a
doi: 10.1176/appi.ajp.158.3.497-a
pubmed: 11229999
MacKenzie RG, Heischober B (1997) Methamphetamine. Pediatr Rev 18(9):305–309. https://doi.org/10.1542/pir.18-9-305
doi: 10.1542/pir.18-9-305
pubmed: 9286149
Chen CK, Lin SK, Sham PC, Ball D, Loh EW, Hsiao CC et al (2003) Pre-morbid characteristics and co-morbidity of methamphetamine users with and without psychosis. Psychol Med 33(8):1407–1414. https://doi.org/10.1017/s0033291703008353
doi: 10.1017/s0033291703008353
pubmed: 14672249
Yamamuro K, Kimoto S, Iida J, Kishimoto N, Nakanishi Y, Tanaka S et al (2016) Reduced prefrontal cortex hemodynamic response in adults with methamphetamine induced psychosis: relevance for impulsivity. PLoS One 11(4):e0152373. https://doi.org/10.1371/journal.pone.0152373
doi: 10.1371/journal.pone.0152373
pubmed: 27050450
pmcid: 4822936
Fuentes D, Tavares H, Artes R, Gorenstein C (2006) Self-reported and neuropsychological measures of impulsivity in pathological gambling. J Int Neuropsychol Soc 12(6):907–912. https://doi.org/10.1017/S1355617706061091
doi: 10.1017/S1355617706061091
pubmed: 17064453
Petry NM (2001) Substance abuse, pathological gambling, and impulsiveness. Drug Alcohol Depend 63(1):29–38. https://doi.org/10.1016/s0376-8716(00)00188-5
doi: 10.1016/s0376-8716(00)00188-5
pubmed: 11297829
Clark L, Limbrick-Oldfield EH (2013) Disordered gambling: a behavioral addiction. Curr Opin Neurobiol 23(4):655–659. https://doi.org/10.1016/j.conb.2013.01.004
doi: 10.1016/j.conb.2013.01.004
pubmed: 23375671
Grant JE, Chamberlain SR (2014) Impulsive action and impulsive choice across substance and behavioral addictions: cause or consequence? Addict Behav 39(11):1632–1639. https://doi.org/10.1016/j.addbeh.2014.04.022
doi: 10.1016/j.addbeh.2014.04.022
pubmed: 24864028
Reuter J, Raedler T, Rose M, Hand I, Glascher J, Buchel C (2005) Pathological gambling is linked to reduced activation of the mesolimbic reward system. Nat Neurosci 8(2):147–148. https://doi.org/10.1038/nn1378
doi: 10.1038/nn1378
pubmed: 15643429
de Ruiter MB, Veltman DJ, Goudriaan AE, Oosterlaan J, Sjoerds Z, van den Brink W (2009) Response perseveration and ventral prefrontal sensitivity to reward and punishment in male problem gamblers and smokers. Neuropsychopharmacology 34(4):1027–1038. https://doi.org/10.1038/npp.2008.175
doi: 10.1038/npp.2008.175
pubmed: 18830241
Okada N, Takahashi K, Nishimura Y, Koike S, Ishii-Takahashi A, Sakakibara E et al (2016) Characterizing prefrontal cortical activity during inhibition task in methamphetamine-associated psychosis versus schizophrenia: a multi-channel near-infrared spectroscopy study. Addict Biol 21(2):489–503. https://doi.org/10.1111/adb.12224
doi: 10.1111/adb.12224
pubmed: 25619621
Bickel WK, Yi R, Landes RD, Hill PF, Baxter C (2011) Remember the future: working memory training decreases delay discounting among stimulant addicts. Biol Psychiatry 69(3):260–265. https://doi.org/10.1016/j.biopsych.2010.08.017
doi: 10.1016/j.biopsych.2010.08.017
pubmed: 20965498
Fitzpatrick RE, Rubenis AJ, Lubman DI, Verdejo-Garcia A (2020) Cognitive deficits in methamphetamine addiction: independent contributions of dependence and intelligence. Drug Alcohol Depend 209:107891. https://doi.org/10.1016/j.drugalcdep.2020.107891
doi: 10.1016/j.drugalcdep.2020.107891
pubmed: 32061948
Gan H, Song Z, Xu P, Su H, Pan Y, Zhao M et al (2018) A comparison study of working memory deficits between patients with methamphetamine-associated psychosis and patients with schizophrenia. Shanghai Arch Psychiatry 30(3):168–177. https://doi.org/10.11919/j.issn.1002-0829.217166
doi: 10.11919/j.issn.1002-0829.217166
pubmed: 30858668