Urine metabolic phenotyping in children with nocturnal enuresis and comorbid neurobehavioral disorders.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
16 08 2021
Historique:
received: 10 05 2021
accepted: 03 08 2021
entrez: 17 8 2021
pubmed: 18 8 2021
medline: 16 11 2021
Statut: epublish

Résumé

Nocturnal enuresis (NE) is a common problem among 10% school-aged children. The etiologies underlying childhood NE is complex and not fully understood nowadays. Nevertheless, increasing evidence suggests a potential link between neurobehavioral disorders and enuresis in children. In this study, we aimed to explore novel metabolomic insights into the pathophysiology of NE and also, its association with pediatric psychiatric problems. Urine collected from 41 bedwetting children and 27 healthy control children was analyzed by using

Identifiants

pubmed: 34400733
doi: 10.1038/s41598-021-96104-1
pii: 10.1038/s41598-021-96104-1
pmc: PMC8368245
doi:

Substances chimiques

Betaine 3SCV180C9W

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

16592

Informations de copyright

© 2021. The Author(s).

Références

Neurourol Urodyn. 2016 Apr;35(4):471-81
pubmed: 25772695
J Urol. 2010 Feb;183(2):441-7
pubmed: 20006865
BJU Int. 2004 Feb;93(3):341-5
pubmed: 14764133
Neurochem Res. 2017 Jun;42(6):1697-1709
pubmed: 28417264
J Urol. 2004 Jun;171(6 Pt 2):2576-9
pubmed: 15118422
J Investig Med. 2017 Feb;65(2):370-375
pubmed: 27733442
Reprod Toxicol. 2015 Aug 15;56:155-69
pubmed: 26021712
Cardiovasc Drugs Ther. 2014 Oct;28(5):459-68
pubmed: 25060556
Metabolomics. 2017;13(4):36
pubmed: 28261014
Pediatrics. 2019 Oct;144(4):
pubmed: 31570648
Eur J Pharmacol. 2019 Apr 5;848:39-48
pubmed: 30689995
J Physiol. 2010 Sep 15;588(Pt 18):3355-64
pubmed: 20498228
Front Immunol. 2018 May 24;9:1070
pubmed: 29881379
Arch Gen Psychiatry. 1992 Sep;49(9):728-38
pubmed: 1514878
Eur J Pediatr. 2016 Jun;175(6):747-54
pubmed: 27138767
Dev Med Child Neurol. 1989 Dec;31(6):728-36
pubmed: 2599267
J Urol. 2008 Jun;179(6):2389-95
pubmed: 18433780
Am J Physiol Renal Physiol. 2006 Dec;291(6):F1232-40
pubmed: 16804103
Am J Clin Nutr. 2004 Sep;80(3):539-49
pubmed: 15321791
Anal Chem. 2008 May 15;80(10):3783-90
pubmed: 18419139
J Am Soc Nephrol. 2014 Jul;25(7):1430-9
pubmed: 24652800
Sci Rep. 2019 Sep 24;9(1):13764
pubmed: 31551443
Psychiatr Neurol Med Psychol (Leipz). 1985 Apr;37(4):221-7
pubmed: 4001233
Curr Pharm Des. 2020;26(37):4699-4711
pubmed: 32418522
Cells. 2019 Dec 11;8(12):
pubmed: 31835795
J Pediatr. 2009 Aug;155(2):239-44.e5
pubmed: 19446845
Front Physiol. 2014 Apr 24;5:159
pubmed: 24795654
J Urol. 2016 Jan;195(1):162-7
pubmed: 26192252
Pediatr Nephrol. 2013 Jul;28(7):1099-103
pubmed: 23512258
Acta Paediatr. 2007 Feb;96(2):242-5
pubmed: 17429913
Ann West Med Surg. 1951 Oct;5(10):825-9
pubmed: 14878413
EBioMedicine. 2019 Jul;45:432-446
pubmed: 31255657
Int J Urol. 2017 Mar;24(3):174-182
pubmed: 28208214
J Biol Chem. 1946 Oct;165(2):639-48
pubmed: 20276130
BJU Int. 2006 May;97(5):1069-73
pubmed: 16643494
Scand J Urol Nephrol. 2008;42(3):257-64
pubmed: 18432533
J Am Acad Child Adolesc Psychiatry. 2009 Jan;48(1):35-41
pubmed: 19096296
Nephrol Dial Transplant. 2018 Dec 1;33(12):2156-2164
pubmed: 29554320
Neurochem Int. 2012 May;60(6):597-604
pubmed: 22391325
Nutrients. 2017 Jul 28;9(8):
pubmed: 28788094
Nat Rev Drug Discov. 2015 Jul;14(7):461-74
pubmed: 26000723
Br J Urol. 1996 Oct;78(4):602-6
pubmed: 8944518
Sci Rep. 2016 Apr 22;6:24930
pubmed: 27103079
Neurochem Res. 2017 Dec;42(12):3490-3503
pubmed: 28918494
Acta Paediatr. 2006 Mar;95(3):347-52
pubmed: 16497647

Auteurs

Mei-Ching Yu (MC)

Division of Pediatric Nephrology, Department of Pediatrics, Lin-Kou Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, 5, Fusing Street, Gueishan, Taoyuan, 333, Taiwan. mc.yu@cgmh.org.tw.

Ta-Min Wang (TM)

Division of Pediatric Urology, Department of Urology, Lin-Kou Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Taoyuan, Taiwan.

Yee-Hsuan Chiou (YH)

Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Meng-Kung Yu (MK)

Department of Pediatrics, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung, Taiwan.

Chiao-Fan Lin (CF)

Department of Child and Adolescent Psychiatry, Lin-Kou Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Chih-Yung Chiu (CY)

Division of Pediatric Pulmonology, Department of Pediatrics, Clinical Metabolomics Core Laboratory, Lin-Kou Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, 5, Fusing Street, Gueishan, Taoyuan, 333, Taiwan. pedchestic@gmail.com.

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