Function of K2P channels in the mammalian node of Ranvier.
K2P channels
Na channels
action potential
mammalian myelinated nerve fiber
node of Ranvier
Journal
The Journal of physiology
ISSN: 1469-7793
Titre abrégé: J Physiol
Pays: England
ID NLM: 0266262
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
received:
15
06
2021
accepted:
09
08
2021
pubmed:
24
8
2021
medline:
28
10
2021
entrez:
23
8
2021
Statut:
ppublish
Résumé
In myelinated nerve fibres, action potentials are generated at nodes of Ranvier. These structures are located at interruptions of the myelin sheath, forming narrow gaps with small rings of axolemma freely exposed to the extracellular space. The mammalian node contains a high density of Na
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
4427-4439Informations de copyright
© 2021 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.
Références
Aman TK, Grieco-Calub TM, Chen C, Rusconi R, Slat EA, Isom LL & Raman IM (2009). Regulation of persistent Na current by interactions between β subunits of voltage-gated Na channels. J Neurosci 29, 2027-2042.
Baker MD & Bostock H (1997). Low-threshold, persistent sodium current in rat large dorsal root ganglion neurons in culture. J Neurophysiol 77, 1503-1513.
Battefeld A, Tran BT, Gavrilis J, Cooper EC & Kole MH (2014). Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons. J Neurosci 34, 3719-3732.
Bauer CK, Calligari P, Radio FC, Caputo V, Dentici ML, Falah N, High F, Pantaleoni F, Barresi S, Ciolfi A, Pizzi S, Bruselles A, Person R, Richards S, Cho MT, Sepulveda DJC, Pro S, Battini R, Zampino G, Digilio MC, Bocchinfuso G, Dallapiccola B, Stella L & Tartaglia M (2018). Mutations in KCNK4 that affect gating cause a recognizable neurodevelopmental syndrome. Am J Hum Genet 103, 621-630.
Berthold C-H& Rydmark M (1995). Morphology of normal peripheral axons. In The Axon, eds Waxman SG, Kocsis JD & Stys PK. Oxford University Press, New York, Oxford.13-48.
Biel M, Wahl-Schott C, Michalakis S & Zong X (2009). Hyperpolarization-activated cation channels: from genes to function. Physiol Rev 89, 847-885.
Bostock H & Rothwell JC (1997). Latent addition in motor and sensory fibres of human peripheral nerve. J Physiol 498, 277-294.
Brickley SG, Aller MI, Sandu C, Veale EL, Alder FG, Sambi H, Mathie A & Wisden W (2007). TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons. J Neurosci 27, 9329-9340.
Brismar T (1980). Potential clamp analysis of membrane currents in rat myelinated nerve fibres. J Physiol 298, 171-184.
Brohawn SG, Wang W, Handler A, Campbell EB, Schwarz JR & MacKinnon R (2019). The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier. Elife 8, e50403.
Brown DA & Passmore GM (2009). Neural KCNQ (Kv7) channels. Br J Pharmacol 156, 1185-1195.
Browne DL, Gancher ST, Nutt JG, Brunt ER, Smith EA, Kramer P & Litt M (1994). Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1. Nat Genet 8, 136-140.
Buffington SA & Rasband MN (2013). Na+ channel-dependent recruitment of Navbeta4 to axon initial segments and nodes of Ranvier. J Neurosci 33, 6191-6202.
Burke, D, Kiernan, MC & Bostock, H (2001). Excitability of human axons. Clin Neurophysiol, 112, 1575-1585.
Chiu SY (2005). The roles of potassium and calcium channels in physiology and pathophysiology of axons. In Multiple Sclerosis as a Neuronal Disease, ed Waxman SG, pp. 69-83. Elsevier, Amsterdam, Boston.
Chiu SY & Ritchie JM (1981). Evidence for the presence of potassium channels in the paranodal region of acutely demyelinated mammalian single nerve fibres. J Physiol 313, 415-437.
Chiu SY, Ritchie JM, Rogart RB & Stagg D (1979). A quantitative description of membrane currents in rabbit myelinated nerve. J Physiol 292, 149-166.
Cohen CCH, Popovic MA, Klooster J, Weil MT, Mobius W, Nave KA & Kole MHP (2020). Saltatory conduction along myelinated axons involves a periaxonal nanocircuit. Cell 180, 311-322.e15.
D'Este E, Kamin D, Balzarotti F & Hell SW (2017). Ultrastructural anatomy of nodes of Ranvier in the peripheral nervous system as revealed by STED microscopy. Proc Natl Acad Sci U S A 114, E191-E199.
Dedek K, Kunath B, Kananura C, Reuner U, Jentsch TJ & Steinlein OK (2001). Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel. Proc Natl Acad Sci U S A 98, 12272-12277.
Devaux J, Alcaraz G, Grinspan J, Bennett V, Joho R, Crest M & Scherer SS (2003). Kv3.1b is a novel component of CNS nodes. J Neurosci 23, 4509-4518.
Devaux JJ, Kleopa KA, Cooper EC & Scherer SS (2004). KCNQ2 is a nodal K+ channel. J Neurosci 24, 1236-1244.
Enyedi P & Czirjak G (2010). Molecular background of leak K+ currents: two-pore domain potassium channels. Physiol Rev 90, 559-605.
Fink M, Lesage F, Duprat F, Heurteaux C, Reyes R, Fosset M & Lazdunski M (1998). A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids. EMBO J 17, 3297-3308.
Frankenhaeuser B & Huxley AF (1964). The action potential in the myelinated nerve fiber of Xenopus laevis as computed on the basis of voltage clamp data. J Physiol 171, 302-315.
Gonzalez JA, Jensen LT, Doyle SE, Miranda-Anaya M, Menaker M, Fugger L, Bayliss DA & Burdakov D (2009). Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons. Eur J Neurosci 30, 57-64.
Grundemann J & Clark BA (2015). Calcium-activated potassium channels at nodes of Ranvier secure axonal spike propagation. Cell Rep 12, 1715-1722.
Hodgkin AL & Huxley AF (1952). A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117, 500-544.
Howells J, Trevillion L, Bostock H & Burke D (2012). The voltage dependence of Ih in human myelinated axons. J Physiol 590, 1625-1640.
Huxley AF & Stampfli R (1949). Evidence for saltatory conduction in peripheral myelinated nerve fibres. J Physiol 108, 315-339.
Iwasa K, Tasaki I & Gibbons RC (1980). Swelling of nerve fibers associated with action potentials. Science 210, 338-339.
Jonas P, Brau ME, Hermsteiner M & Vogel W (1989). Single-channel recording in myelinated nerve fibers reveals one type of Na channel but different K channels. Proc Natl Acad Sci U S A 86, 7238-7242.
Kanda H, Ling J, Tonomura S, Noguchi K, Matalon S & Gu JG (2019). TREK-1 and TRAAK are principal K+ channels at the nodes of Ranvier for rapid action potential conduction on mammalian myelinated afferent nerves. Neuron 104, 960-971.e7.
Kole MH (2011). First node of Ranvier facilitates high-frequency burst encoding. Neuron 71, 671-682.
Leterrier C (2018). The axon initial segment: an updated viewpoint. J Neurosci 38, 2135-2145.
MacKenzie G, Franks NP & Brickley SG (2015). Two-pore domain potassium channels enable action potential generation in the absence of voltage-gated potassium channels. Pflugers Arch 467, 989-999.
Maingret F, Fosset M, Lesage F, Lazdunski M & Honore E (1999). TRAAK is a mammalian neuronal mechano-gated K+ channel. J Biol Chem 274, 1381-1387.
Neumcke B & Stampfli R (1982). Sodium currents and sodium-current fluctuations in rat myelinated nerve fibres. J Physiol 329, 163-184.
Noel J, Zimmermann K, Busserolles J, Deval E, Alloui A, Diochot S, Guy N, Borsotto M, Reeh P, Eschalier A & Lazdunski M (2009). The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception. EMBO J 28, 1308-1318.
Nonner W (1969). A new voltage clamp method for Ranvier nodes. Pflugers Arch 309, 176-192.
Nonner W & Stämpfli R (1969). A new voltage clamp method. In Laboratory Techniques in Membrane Biophysics, eds Passow H & Stämpfli R, pp. 171-175. Springer-Verlag, Berlin, Heidelberg.
Ona-Jodar T, Gerkau NJ, Sara Aghvami S, Rose CR & Egger V (2017). Two-photon Na+ imaging reports somatically evoked action potentials in rat olfactory bulb mitral and granule cell neurites. Front Cell Neurosci 11, 50.
Rasband MN & Peles E (2021). Mechanisms of node of Ranvier assembly. Nat Rev Neurosci 22, 7-20.
Renigunta V, Schlichthorl G & Daut J (2015). Much more than a leak: structure and function of K2P-channels. Pflugers Arch 467, 867-894.
Roper J & Schwarz JR (1989). Heterogeneous distribution of fast and slow potassium channels in myelinated rat nerve fibres. J Physiol 416, 93-110.
Rudy B & McBain CJ (2001). Kv3 channels: voltage-gated K+ channels designed for high-frequency repetitive firing. Trends Neurosci 24, 517-526.
Schewe M, Nematian-Ardestani E, Sun H, Musinszki M, Cordeiro S, Bucci G, de Groot BL, Tucker SJ, Rapedius M & Baukrowitz T (2016). A non-canonical voltage-sensing mechanism controls gating in K2P K(+) Channels. Cell 164, 937-949.
Schwarz JR & Eikhof G (1987). Na currents and action potentials in rat myelinated nerve fibres at 20 and 37° C. Pflugers Arch 409, 569-577.
Schwarz JR, Glassmeier G, Cooper EC, Kao TC, Nodera H, Tabuena D, Kaji R & Bostock H (2006). KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier. J Physiol 573, 17-34.
Schwarz JR, Reid G & Bostock H (1995). Action potentials and membrane currents in the human node of Ranvier. Pflugers Arch 430, 283-292.
Stämpfli R & Hille B (1976). Electrophysiology of the peripheral myelinated nerve. In Frog Neurobiology, eds Llinas R & Precht W. pp. 3-32. Springer, Berlin, Heidelberg.
Su Z, Brown EC, Wang W & MacKinnon R (2016). Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels. Proc Natl Acad Sci U S A 113, 5748-5753.
Vogel W & Schwarz JR (1995). Voltage-clamp studies in axons: macroscopic and single-channel currents. In The Axon, eds Waxman SG, Kocsis JD & Stys PK, pp 257-280. Oxford University Press, New York, Oxford.
Zhang Z & David G (2016). Stimulation-induced Ca2+ influx at nodes of Ranvier in mouse peripheral motor axons. J Physiol 594, 39-57.
Zhou L, Zhang CL, Messing A & Chiu SY (1998). Temperature-sensitive neuromuscular transmission in Kv1.1 null mice: role of potassium channels under the myelin sheath in young nerves. J Neurosci 18, 7200-7215.