Lateral hypothalamic LEPR neurons drive appetitive but not consummatory behaviors.
appetitive behaviors
chemogenetics
consummatory behaviors
functional imaging
lateral hypothalamus
leptin receptor
neuronal circuits
optogenetics
ventral tegmental area
Journal
Cell reports
ISSN: 2211-1247
Titre abrégé: Cell Rep
Pays: United States
ID NLM: 101573691
Informations de publication
Date de publication:
24 08 2021
24 08 2021
Historique:
received:
15
01
2021
revised:
28
05
2021
accepted:
05
08
2021
entrez:
25
8
2021
pubmed:
26
8
2021
medline:
12
2
2022
Statut:
ppublish
Résumé
Assigning behavioral roles to genetically defined neurons within the lateral hypothalamus (LH) is an ongoing challenge. We demonstrate that a subpopulation of LH GABAergic neurons expressing leptin receptors (LH
Identifiants
pubmed: 34433027
pii: S2211-1247(21)01053-6
doi: 10.1016/j.celrep.2021.109615
pmc: PMC8423025
mid: NIHMS1735657
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
109615Subventions
Organisme : Intramural NIH HHS
ID : ZIA DA000595
Pays : United States
Informations de copyright
Published by Elsevier Inc.
Déclaration de conflit d'intérêts
Declaration of interests The authors declare no competing interests.
Références
Eur J Neurosci. 2012 Oct;36(8):3126-33
pubmed: 22775118
Nat Neurosci. 2016 Feb;19(2):198-205
pubmed: 26814589
Nat Neurosci. 2019 Apr;22(4):642-656
pubmed: 30858605
Nat Neurosci. 2016 Apr;19(4):554-6
pubmed: 26950004
Cell. 2013 May 9;153(4):896-909
pubmed: 23663785
Nat Protoc. 2006;1(1):122-4
pubmed: 17406223
Nature. 2013 Jul 18;499(7458):295-300
pubmed: 23868258
Obesity (Silver Spring). 2006 Aug;14 Suppl 5:208S-212S
pubmed: 17021368
Psychopharmacology (Berl). 2013 Feb;225(4):791-801
pubmed: 22993050
PLoS Genet. 2017 Jul 13;13(7):e1006780
pubmed: 28704371
Front Syst Neurosci. 2015 Feb 18;9:9
pubmed: 25741247
Nature. 2014 Apr 10;508(7495):207-14
pubmed: 24695228
Cell Metab. 2011 Sep 7;14(3):313-23
pubmed: 21907138
Psychopharmacology (Berl). 2012 Aug;222(3):447-57
pubmed: 22418731
Sci Rep. 2019 Feb 12;9(1):1873
pubmed: 30755658
Nat Neurosci. 2018 Aug;21(8):1084-1095
pubmed: 30038273
Cell Metab. 2009 Aug;10(2):89-98
pubmed: 19656487
PLoS One. 2019 Jul 10;14(7):e0219522
pubmed: 31291348
Science. 2017 Aug 4;357(6350):503-507
pubmed: 28774929
Neuron. 2018 Feb 21;97(4):898-910.e6
pubmed: 29398355
Nat Protoc. 2006;1(4):1662-70
pubmed: 17487149
Nature. 2017 Sep 28;549(7673):482-487
pubmed: 28902835
Cell Rep. 2018 Jun 19;23(12):3673-3684
pubmed: 29925007
J Neurosci. 2017 Jun 21;37(25):6053-6065
pubmed: 28539422
Cell. 2015 Jan 29;160(3):516-27
pubmed: 25635459
J Neurosci. 2016 Mar 9;36(10):2975-85
pubmed: 26961951
Learn Mem. 2015 Mar 18;22(4):232-8
pubmed: 25787711
Science. 2017 May 26;356(6340):853-859
pubmed: 28546212
Obesity (Silver Spring). 2019 Jul;27(7):1123-1132
pubmed: 31087767
Mol Metab. 2015 Jul 16;4(10):706-17
pubmed: 26500842
J Physiol. 2016 Nov 15;594(22):6443-6462
pubmed: 27302606
Neuropsychopharmacology. 2002 Jan;26(1):130-4
pubmed: 11751040
Front Neural Circuits. 2012 Jul 27;6:47
pubmed: 22866029
Nat Rev Genet. 2017 Jan;18(1):24-40
pubmed: 27795562
PLoS One. 2020 Jan 27;15(1):e0224301
pubmed: 31986148
Eur J Pharmacol. 2011 May 11;658(2-3):156-9
pubmed: 21371470
J Clin Invest. 2011 Apr;121(4):1424-8
pubmed: 21364278
Biol Psychiatry. 2018 Jun 15;83(12):1012-1023
pubmed: 29452828
Science. 2013 Sep 27;341(6153):1517-21
pubmed: 24072922
Neurosci Lett. 2014 Apr 30;566:67-71
pubmed: 24561093
Neuropsychopharmacology. 2016 May;41(6):1505-12
pubmed: 26442599
Cell. 2015 Jan 29;160(3):528-41
pubmed: 25635460
Science. 1997 Mar 14;275(5306):1593-9
pubmed: 9054347
eNeuro. 2016 Nov 1;3(5):
pubmed: 27822508
Neuron. 2016 Jun 15;90(6):1286-1298
pubmed: 27238864
Curr Biol. 2017 Jul 24;27(14):2089-2100.e5
pubmed: 28690111
Pharmacol Rev. 2011 Jun;63(2):348-65
pubmed: 21490129