Nitro-Oleic Acid (NO

Animals Anti-Inflammatory Agents / pharmacology Cardiomyopathy, Dilated / drug therapy Drug Evaluation, Preclinical Fibroblasts / metabolism Fibrosis Heart / drug effects LIM Domain Proteins / genetics Mice Muscle Proteins / genetics Myocardium / metabolism Nitro Compounds / pharmacology Oleic Acids / pharmacology Transforming Growth Factor beta / metabolism Ventricular Function, Left / drug effects
TGFβ alpha smooth muscle actin dilated cardiomyopathy muscle LIM protein myocardial fibrosis nitro-oleic acid

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
22 Aug 2021
Historique:
received: 06 08 2021
revised: 17 08 2021
accepted: 18 08 2021
entrez: 27 8 2021
pubmed: 28 8 2021
medline: 30 9 2021
Statut: epublish

Résumé

Nitro-oleic acid (NO

Identifiants

DOI: 10.3390/ijms22169052 PMID: 34445757 PMC: PMC8396484
pubmed: 34445757
pii: ijms22169052
doi: 10.3390/ijms22169052
pmc: PMC8396484
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents 0
LIM Domain Proteins 0
Muscle Proteins 0
Nitro Compounds 0
Oleic Acids 0
Transforming Growth Factor beta 0
cysteine and glycine-rich protein 3 0
CXA-10 1N19AGY57Y

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : GRK 2407 (360043781)
Organisme : Deutsche Forschungsgemeinschaft
ID : SFB TRR259 (397484323 - project B04)
Organisme : Deutsche Forschungsgemeinschaft
ID : SFB TRR259 (397484323 - project B05)
Organisme : Deutsche Forschungsgemeinschaft
ID : RU1678/3-3
Organisme : Deutsche Forschungsgemeinschaft
ID : MO 3438/2-1

Références

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Auteurs

Simon Braumann (S)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.

Wibke Schumacher (W)

Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.
Cologne Cardiovascular Research Center (CCRC), Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.

Nam Gyu Im (NG)

Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.

Felix Sebastian Nettersheim (FS)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.

Dennis Mehrkens (D)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.
Cologne Cardiovascular Research Center (CCRC), Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
ORCID: 0000-0002-8578-0290

Senai Bokredenghel (S)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.

Alexander Hof (A)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.
ORCID: 0000-0001-6554-8892

Richard Julius Nies (RJ)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.

Christoph Adler (C)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.

Holger Winkels (H)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
ORCID: 0000-0003-1333-2031

Ralph Knöll (R)

Department of Medicine, Integrated Cardio Metabolic Centre (ICMC), Heart and Vascular Theme, Karolinska Institute, 17177 Stockholm, Sweden.
Bioscience, Cardiovascular, Renal & Metabolism, BioPharmaceuticals R&D, AstraZeneca, 43150 Mölndal, Sweden.

Bruce A Freeman (BA)

Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
ORCID: 0000-0002-2028-8369

Volker Rudolph (V)

Cologne Cardiovascular Research Center (CCRC), Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.
Agnes Wittenborg Institute for Translational Cardiovascular Research, Clinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum NRW, University Hospital of the Ruhr-Universität Bochum, 32545 Bad Oeynhausen, Germany.

Anna Klinke (A)

Agnes Wittenborg Institute for Translational Cardiovascular Research, Clinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum NRW, University Hospital of the Ruhr-Universität Bochum, 32545 Bad Oeynhausen, Germany.

Matti Adam (M)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.

Stephan Baldus (S)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.
Cologne Cardiovascular Research Center (CCRC), Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.

Martin Mollenhauer (M)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.
ORCID: 0000-0002-3220-9269

Simon Geißen (S)

Department of Cardiology, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine and Faculty of Mathematics and Natural Sciences, University of Cologne, 50937 Cologne, Germany.
Cologne Cardiovascular Research Center (CCRC), Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Nitro-Oleic Acid (NO
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-inflammatoires › Nitro-Oleic Acid (NO
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Laminopathies › Cardiomyopathie dilatée › Nitro-Oleic Acid (NO
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Nitro-Oleic Acid (NO
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Nitro-Oleic Acid (NO
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Fibrose › Nitro-Oleic Acid (NO
questionsmedicales.fr › Système cardiovasculaire › Coeur › Nitro-Oleic Acid (NO
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines à domaine LIM › Nitro-Oleic Acid (NO
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Nitro-Oleic Acid (NO
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines contractiles › Protéines du muscle › Nitro-Oleic Acid (NO
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Myocarde › Nitro-Oleic Acid (NO
questionsmedicales.fr › Composés chimiques organiques › Composés nitrés › Nitro-Oleic Acid (NO
questionsmedicales.fr › Lipides › Acides gras › Acides gras insaturés › Acides gras monoinsaturés › Acides oléiques › Nitro-Oleic Acid (NO
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Protéines de la superfamille du TGF bêta › Facteur de croissance transformant bêta › Nitro-Oleic Acid (NO
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction ventriculaire › Fonction ventriculaire gauche › Nitro-Oleic Acid (NO