Efficient Pseudotyping of Different Retroviral Vectors Using a Novel, Codon-Optimized Gene for Chimeric GALV Envelope.
GMP
T-cell receptor (TCR)
adoptive immunotherapy
chimeric antigen receptor (CAR)
gene therapy
pseudotyping
retroviral vectors
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
27 07 2021
27 07 2021
Historique:
received:
04
06
2021
revised:
21
07
2021
accepted:
25
07
2021
entrez:
28
8
2021
pubmed:
29
8
2021
medline:
3
2
2022
Statut:
epublish
Résumé
The Gibbon Ape Leukemia Virus envelope protein (GALV-Env) mediates efficient transduction of human cells, particularly primary B and T lymphocytes, and is therefore of great interest in gene therapy. Using internal domains from murine leukemia viruses (MLV), chimeric GALV-Env proteins such as GALV-C
Identifiants
pubmed: 34452336
pii: v13081471
doi: 10.3390/v13081471
pmc: PMC8402753
pii:
doi:
Substances chimiques
Codon
0
Receptors, Chimeric Antigen
0
Viral Envelope Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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