Retrospective Study of the Upsurge of Enterovirus D68 Clade D1 among Adults (2014-2018).
Adult
Aged
Central Nervous System Viral Diseases
/ epidemiology
Child, Preschool
DNA, Viral
/ genetics
Enterovirus D, Human
/ classification
Enterovirus Infections
/ complications
Female
France
/ epidemiology
Genome, Viral
Humans
Infant
Male
Middle Aged
Myelitis
/ epidemiology
Neuromuscular Diseases
/ epidemiology
Phylogeny
Prospective Studies
Respiratory Tract Infections
/ epidemiology
Retrospective Studies
adult patients
enterovirus D68
molecular epidemiology
next-generation sequencing
paediatric patients
respiratory conditions
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
13 08 2021
13 08 2021
Historique:
received:
06
07
2021
revised:
26
07
2021
accepted:
08
08
2021
entrez:
28
8
2021
pubmed:
29
8
2021
medline:
28
1
2022
Statut:
epublish
Résumé
Enterovirus D68 (EV-D68) has emerged as an agent of epidemic respiratory illness and acute flaccid myelitis in the paediatric population but data are lacking in adult patients. We performed a 4.5-year single-centre retrospective study of all patients who tested positive for EV-D68 and analysed full-length EV-D68 genomes of the predominant clades B3 and D1. Between 1 June 2014, and 31 December 2018, 73 of the 11,365 patients investigated for respiratory pathogens tested positive for EV-D68, of whom 20 (27%) were adults (median age 53.7 years [IQR 34.0-65.7]) and 53 (73%) were children (median age 1.9 years [IQR 0.2-4.0]). The proportion of adults increased from 12% in 2014 to 48% in 2018 (
Identifiants
pubmed: 34452471
pii: v13081607
doi: 10.3390/v13081607
pmc: PMC8402803
pii:
doi:
Substances chimiques
DNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Commentaires et corrections
Type : CommentIn
Références
J Virol. 2015 Dec 09;90(4):1997-2007
pubmed: 26656685
Science. 2015 Jan 2;347(6217):71-4
pubmed: 25554786
mBio. 2019 Aug 13;10(4):
pubmed: 31409689
J Gen Virol. 2004 Sep;85(Pt 9):2577-2584
pubmed: 15302951
Euro Surveill. 2019 Jan;24(3):
pubmed: 30670143
Bioinformatics. 2018 Dec 1;34(23):4121-4123
pubmed: 29790939
Front Immunol. 2018 Jul 20;9:1653
pubmed: 30079065
Genome Res. 2004 Jun;14(6):1188-90
pubmed: 15173120
Lancet Infect Dis. 2018 Aug;18(8):e239-e247
pubmed: 29482893
Eur Respir Rev. 2019 Mar 14;28(151):
pubmed: 30872396
Euro Surveill. 2016 May 12;21(19):
pubmed: 27195770
J Clin Microbiol. 2020 Aug 24;58(9):
pubmed: 32493783
Clin Infect Dis. 2019 Jul 2;69(2):197-203
pubmed: 30452608
J Virol. 2017 Aug 24;91(18):
pubmed: 28659472
Medicine (Baltimore). 2016 Aug;95(31):e4416
pubmed: 27495059
Euro Surveill. 2018 Sep;23(37):
pubmed: 30229724
Emerg Microbes Infect. 2019;8(1):1438-1444
pubmed: 31571527
Euro Surveill. 2014 Nov 06;19(44):
pubmed: 25394254
PLoS Comput Biol. 2014 Apr 10;10(4):e1003537
pubmed: 24722319
Emerg Infect Dis. 2019 Jun;25(6):1200-1203
pubmed: 30855226
PLoS One. 2015 Dec 02;10(12):e0144208
pubmed: 26630383
Euro Surveill. 2016 May 12;21(19):
pubmed: 27195917
Euro Surveill. 2019 Aug;24(35):
pubmed: 31481149
Sci Rep. 2016 Apr 28;6:25147
pubmed: 27121085
Euro Surveill. 2019 Feb;24(7):
pubmed: 30782269
J Gen Virol. 2002 Feb;83(Pt 2):333-340
pubmed: 11807226
Int J Mol Sci. 2017 May 16;18(5):
pubmed: 28509856
Emerg Infect Dis. 2019 Mar;25(3):585-588
pubmed: 30789123
Lancet Infect Dis. 2016 May;16(5):e64-e75
pubmed: 26929196
Int J Mol Sci. 2020 Apr 22;21(8):
pubmed: 32331343
Euro Surveill. 2018 Feb;23(7):
pubmed: 29471623
Syst Biol. 2010 May;59(3):307-21
pubmed: 20525638