Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
27 08 2021
Historique:
received: 25 02 2021
accepted: 11 08 2021
entrez: 28 8 2021
pubmed: 29 8 2021
medline: 9 11 2021
Statut: epublish

Résumé

This study aimed to investigate the incidence of and risk factors for postoperative new-onset deep venous thrombosis (PNO-DVT) following intertrochanteric fracture surgery. Information on 1672 patients who underwent intertrochanteric fracture surgery at our hospital between January 2016 and December 2019 was extracted from a prospective hip fracture database. Demographic information, surgical data, and preoperative laboratory indices were analysed. Receiver operating characteristic curve analysis, univariate analyses and binary logistic regression analyses were performed. The incidences of postoperative deep venous thrombosis (DVT) and PNO-DVT in inpatients after intertrochanteric fracture surgery were 11.5% (202 of 1751 patients) and 7.4% (123 of 1672 patients), respectively. PNO-DVT accounted for 60.9% of postoperative DVT. Additionally, there were 20 cases of central thrombosis (16.3%), 82 cases of peripheral thrombosis (66.7%), and 21 cases of mixed thrombosis (17.1%). In addition, 82.1% of PNO-DVTs were diagnosed within 8 days after surgery. The multivariate analysis revealed that age > 70 years, duration of surgery (> 197 min), type of anaesthesia (general), and comorbidities (≥ 3) were independent risk factors for the development of PNO-DVT after intertrochanteric fracture surgery. This study demonstrated a high incidence of PNO-DVT in inpatients after intertrochanteric fracture surgery. Therefore, postoperative examination for DVT should be routinely conducted for patients.

Identifiants

pubmed: 34453081
doi: 10.1038/s41598-021-96937-w
pii: 10.1038/s41598-021-96937-w
pmc: PMC8397722
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

17319

Informations de copyright

© 2021. The Author(s).

Références

Blood Adv. 2019 Dec 10;3(23):3898-3944
pubmed: 31794602
Cochrane Database Syst Rev. 2004 Oct 18;(4):CD000521
pubmed: 15494999
Med Sci Monit. 2017 Apr 15;23:1819-1826
pubmed: 28411285
Medicine (Baltimore). 2016 Mar;95(9):e3002
pubmed: 26945422
J Bone Joint Surg Am. 2016 Dec 21;98(24):2089-2095
pubmed: 28002372
Injury. 2018 Jul;49(7):1353-1357
pubmed: 29804881
Clin Interv Aging. 2018 Apr 18;13:681-689
pubmed: 29713152
Anesthesiology. 2012 Jul;117(1):72-92
pubmed: 22713634
Arch Orthop Trauma Surg. 2016 Oct;136(10):1459-64
pubmed: 27535672
BMC Anesthesiol. 2020 Apr 2;20(1):72
pubmed: 32241254
Injury. 2015 Apr;46(4):719-23
pubmed: 25704139
BMC Musculoskelet Disord. 2018 Dec 20;19(1):444
pubmed: 30572863
Arch Surg. 1972 Feb;104(2):134-44
pubmed: 5008903
Lancet. 2017 Dec 17;388(10063):3060-3073
pubmed: 27375038
Orthopade. 2018 Apr;47(4):341-346
pubmed: 29556746
Chest. 2012 Feb;141(2 Suppl):e278S-e325S
pubmed: 22315265
J Thromb Haemost. 2014 Oct;12(10):1580-90
pubmed: 25302663
N Engl J Med. 2001 Nov 1;345(18):1298-304
pubmed: 11794148
J Trauma Acute Care Surg. 2013 Jul;75(1):129-34
pubmed: 23940856
Clin Orthop Relat Res. 1990 Jun;(255):198-203
pubmed: 1693325
BMJ Open. 2017 Jun 08;7(6):e016403
pubmed: 28600378
J Arthroplasty. 2017 Apr;32(4):1063-1066
pubmed: 27866951
World J Orthop. 2014 Sep 18;5(4):402-11
pubmed: 25232517
Am J Orthop (Belle Mead NJ). 2007 Jul;36(7):E101-6
pubmed: 17694193
Clin Epidemiol. 2015 Sep 16;7:401-10
pubmed: 26396546
BMC Musculoskelet Disord. 2017 May 22;18(1):208
pubmed: 28532441
Eur J Trauma Emerg Surg. 2016 Aug;42(4):425-431
pubmed: 27418204
JAMA. 2014 Jun 25;311(24):2508-17
pubmed: 25058085
Medicine (Baltimore). 2019 Dec;98(49):e18220
pubmed: 31804347
Arch Orthop Trauma Surg. 2016 May;136(5):639-47
pubmed: 26980097
J Orthop Trauma. 2015 Oct;29(10):e349-54
pubmed: 25816326

Auteurs

Kuo Zhao (K)

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China.
Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.
Orthopaedic Research Institution of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.

Junzhe Zhang (J)

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China.
Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.
Orthopaedic Research Institution of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.

Junyong Li (J)

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China.
Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.
Orthopaedic Research Institution of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.

Hongyu Meng (H)

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China.
Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.
Orthopaedic Research Institution of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.

Zhiyong Hou (Z)

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China.
Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.
Orthopaedic Research Institution of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China.
NHC Key Laboratory of Intelligent Orthopaedic Equipment (The Third Hospital of Hebei Medical University), Shijiazhuang, People's Republic of China.

Yingze Zhang (Y)

Department of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China. suryzz@126.com.
Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China. suryzz@126.com.
Orthopaedic Research Institution of Hebei Province, Shijiazhuang, 050051, Hebei, People's Republic of China. suryzz@126.com.
NHC Key Laboratory of Intelligent Orthopaedic Equipment (The Third Hospital of Hebei Medical University), Shijiazhuang, People's Republic of China. suryzz@126.com.
Chinese Academy of Engineering, Beijing, 10088, People's Republic of China. suryzz@126.com.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH