γ-Lactam-Based Antifungal Compounds against the Wheat Pathogen Zymoseptoria tritici.
Crop protection
antifungal agents
biological screening
green chemistry
γ-lactam
Journal
Chemistry & biodiversity
ISSN: 1612-1880
Titre abrégé: Chem Biodivers
Pays: Switzerland
ID NLM: 101197449
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
24
03
2021
accepted:
30
08
2021
pubmed:
31
8
2021
medline:
8
1
2022
entrez:
30
8
2021
Statut:
ppublish
Résumé
As new environmentally friendly and effective antifungal agents are deeply needed, efficient ecofriendly strategies were designed to access two series of compounds inspired from natural γ-lactams. Designed compounds were fully characterized and evaluated as antifungal candidates against Zymoseptoria tritici, the main pathogen on wheat crops. The targeted derivatives were prepared from natural resources using green solvents, simple procedures, and limited purification steps. These bio-inspired compounds revealed as good candidates for further development of efficient crop protection products. Indeed, the HIT compounds exhibited IC
Identifiants
pubmed: 34460992
doi: 10.1002/cbdv.202100224
doi:
Substances chimiques
Antifungal Agents
0
Lactams
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2100224Subventions
Organisme : Region Hauts de France
Informations de copyright
© 2021 Wiley-VHCA AG, Zurich, Switzerland.
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