A spontaneous retropharyngeal haematoma: a suspected side-effect of indomethacin.
Anti-Inflammatory Agents
Hematoma
Indomethacin
Neck Pain
Non-Steroidal
Journal
The Journal of laryngology and otology
ISSN: 1748-5460
Titre abrégé: J Laryngol Otol
Pays: England
ID NLM: 8706896
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
pubmed:
1
9
2021
medline:
21
10
2021
entrez:
31
8
2021
Statut:
ppublish
Résumé
Retropharyngeal haematomas are most commonly associated with trauma and anti-coagulant use. This paper describes the first reported case of a spontaneous retropharyngeal haematoma suspected to be due to indomethacin use. It is proposed that the combination of indomethacin affecting platelet aggregation, alongside the patient coughing, may have led to this retropharyngeal haematoma. The complexities of management are discussed and the current literature reviewed. In the absence of airway compromise or a rapidly enlarging haematoma, patients can be managed conservatively with observation and close discussion with the haematology department. Follow-up imaging is not necessary if the patient's symptoms settle; however, any increase in parathyroid hormone levels must be investigated to exclude a parathyroid adenoma.
Sections du résumé
BACKGROUND
BACKGROUND
Retropharyngeal haematomas are most commonly associated with trauma and anti-coagulant use. This paper describes the first reported case of a spontaneous retropharyngeal haematoma suspected to be due to indomethacin use.
CASE REPORT
METHODS
It is proposed that the combination of indomethacin affecting platelet aggregation, alongside the patient coughing, may have led to this retropharyngeal haematoma.
CONCLUSION
CONCLUSIONS
The complexities of management are discussed and the current literature reviewed. In the absence of airway compromise or a rapidly enlarging haematoma, patients can be managed conservatively with observation and close discussion with the haematology department. Follow-up imaging is not necessary if the patient's symptoms settle; however, any increase in parathyroid hormone levels must be investigated to exclude a parathyroid adenoma.
Identifiants
pubmed: 34463233
doi: 10.1017/S0022215121001936
pii: S0022215121001936
doi:
Substances chimiques
Indomethacin
XXE1CET956
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM