Viral and bacterial factors of mother-to-child transmission of hepatitis B virus.


Journal

Journal of viral hepatitis
ISSN: 1365-2893
Titre abrégé: J Viral Hepat
Pays: England
ID NLM: 9435672

Informations de publication

Date de publication:
12 2021
Historique:
revised: 30 07 2021
received: 27 05 2021
accepted: 31 07 2021
pubmed: 2 9 2021
medline: 3 2 2022
entrez: 1 9 2021
Statut: ppublish

Résumé

Hepatitis B virus (HBV) infection is the tenth leading cause of death worldwide. Mother-to-child transmission of HBV occurring mainly at delivery remains one of the most common routes of infection in developing countries. One of the main challenges concerning HBV in Africa is to implement a prevention policy aiming at interrupting the cycle of pseudo-vertical transmission of this infection. The aim of this study was to assess the implication of certain bacterial and viral factors in mother-to-child transmission of HBV. This prospective study was conducted on 165 pregnant women carriers of HBV surface antigen (HBsAg) and their 169 newborns who attended care at the Gynecology Department of the University Hospital of Cocody. Serological, molecular, and bacteriological analyses were performed on blood samples and vaginal secretions. Mean viral load (VL) was 4.5 ± 1.3 log

Identifiants

pubmed: 34467609
doi: 10.1111/jvh.13607
doi:

Substances chimiques

DNA, Viral 0
Hepatitis B Surface Antigens 0
Hepatitis B e Antigens 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1683-1689

Informations de copyright

© 2021 John Wiley & Sons Ltd.

Références

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Auteurs

Moussa Doumbia (M)

Bacterial and Viral Serology Laboratory of Institut Pasteur, Abidjan, Ivory Coast.

Daouda Sevede (D)

Bacterial and Viral Serology Laboratory of Institut Pasteur, Abidjan, Ivory Coast.

Viviane Kouakou (V)

Bacterial and Viral Serology Laboratory of Institut Pasteur, Abidjan, Ivory Coast.

Cyprien Kouakou (C)

Neonatology Department, Cocody University Hospital, Abidjan, Ivory Coast.

Frederic Ahoke (F)

UFR Biosciences, University of Cocody, Abidjan, Ivory Coast.

Pascal Pineau (P)

Unité «Organisation Nucléaire et Oncogenèse», INSERM U993, Institut Pasteur, Paris, France.

Mireille Dosso (M)

Bacterial and Viral Serology Laboratory of Institut Pasteur, Abidjan, Ivory Coast.

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