Titre : Antigènes e du virus de l'hépatite virale B

Antigènes e du virus de l'hépatite virale B : Questions médicales fréquentes

Nom anglais: Hepatitis B e Antigens

Descriptor UI: D006513

Tree Number: D23.050.327.495.500.469

Questions fréquentes et termes MeSH associés

Général 1

#1

Erreur lors de la génération.

Veuillez réessayer ultérieurement.
Hepatitis B e Antigens
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Dr Olivier Menir

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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 30/12/2025

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Auteurs principaux

None None

11 publications dans cette catégorie

Publications dans "Antigènes e du virus de l'hépatite virale B" : Voir toutes les publications (11)

Harry L A Janssen

5 publications dans cette catégorie

Affiliations :
  • Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
  • Toronto Centre for Liver Disease, University Health Network, Toronto, Canada.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Marc G Ghany

5 publications dans cette catégorie

Affiliations :
  • Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Sheng-Nan Lu

4 publications dans cette catégorie

Affiliations :
  • Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Wendy C King

4 publications dans cette catégorie

Affiliations :
  • Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Hyun Woong Lee

3 publications dans cette catégorie

Affiliations :
  • Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 03772, Korea.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Rong Fan

3 publications dans cette catégorie

Affiliations :
  • Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Jinlin Hou

3 publications dans cette catégorie

Affiliations :
  • Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
  • Hepatology Unit, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, People's Republic of China.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Jing-Houng Wang

3 publications dans cette catégorie

Affiliations :
  • Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Chao-Hung Hung

3 publications dans cette catégorie

Affiliations :
  • Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Tsung-Hui Hu

3 publications dans cette catégorie

Affiliations :
  • Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Chien-Hung Chen

3 publications dans cette catégorie

Affiliations :
  • Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Rong-Nan Chien

3 publications dans cette catégorie

Affiliations :
  • Liver Research Unit, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taipei, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Qing Xie

3 publications dans cette catégorie

Affiliations :
  • Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Steven H Belle

3 publications dans cette catégorie

Affiliations :
  • Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Jordan J Feld

3 publications dans cette catégorie

Affiliations :
  • Toronto Centre for Liver Disease, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Kathleen B Schwarz

3 publications dans cette catégorie

Affiliations :
  • Johns Hopkins University School of Medicine, Baltimore, Maryland.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Richard K Sterling

3 publications dans cette catégorie

Affiliations :
  • Virginia Commonwealth University, Richmond, Virginia.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Yun-Fan Liaw

3 publications dans cette catégorie

Affiliations :
  • College of Medicine, Chang Gung University, Taoyuan 333323, Taiwan.
  • Division of Hepatology, Department of Hepatogastroenterology, Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Ning-Shao Xia

3 publications dans cette catégorie

Affiliations :
  • School of Public Health, Xiamen University, Xiamen, Fujian, China.
Publications dans "Antigènes e du virus de l'hépatite virale B" :

Sources (10000 au total)

The relationship of maternal hepatitis B e antigen and response to vaccination of infants born to women with chronic infection.

15 Jul 2023
DOI: 10.1186/s12884-023-05815-y PMID: 37454068

The relationship of maternal HBeAg and infants' response to hepatitis B vaccine remains controversial. This study aims to observe the dynamic changes in infant birth HBV markers and study the time-var... 3163 infants born to HBsAg positive mothers including 1737 with maternal HBeAg positive in group A and 1426 negative in group B were enrolled eventually. Demographic information and laboratory tests w... The infant HBV markers at birth displayed different modes. During the follow-up, we observed a significant downward trend in the positive rates of HBsAg, HBeAg, HBeAb and HBcAb. The HBsAg of two group... Maternal HBeAg did affect the infants' immune response to vaccination and reduce the anti-response at 7-12th month temporarily, but these influences were negligible by 24th months after birth, which p...

Pregnancy Infant, Newborn Infant Female Humans +11 autres

A high functional cure rate was induced by pegylated interferon alpha-2b treatment in postpartum hepatitis B e antigen-negative women with chronic hepatitis B virus infection: an exploratory study.

2024
DOI: 10.3389/fcimb.2024.1426960 PMID: 39176265

Limited data have been reported on achieving functional cure using pegylated interferon (Peg-IFN) alpha-2b treatment for postpartum hepatitis B e antigen (HBeAg)-negative women with chronic hepatitis ... A total of 150 HBeAg-negative postpartum women were retrospectively recruited.47 patients received Peg-IFN alpha-2b [Peg-IFN(+) group] and 103 patients did not [Peg-IFN(-) group]. Propensity score mat... At week 48,the HBsAg loss and seroconversion rate in Peg-IFN(+) group were 51.06%(24/47) and 40.43%(19/47), respectively. Even after PSM, Peg-IFN(+) group still showed higher HBsAg loss rate (50.00% v... Peg-IFN alpha-2b treatment could achieve a high rate of HBsAg loss and seroconversion in HBeAg-negative postpartum women with reliable safety, particularly for patients experience postpartum flare and...

Humans Female Hepatitis B, Chronic Polyethylene Glycols Recombinant Proteins +12 autres

Age of hepatitis B e antigen loss in Aboriginal, Torres Strait Islander and non-Indigenous residents of tropical Australia; implications for clinical care.

21 Aug 2024
DOI: 10.33321/cdi.2024.48.48 PMID: 39165023

This study determined the hepatitis B e antigen (HBeAg) status of people living with chronic hepatitis B (CHB) in Far North Queensland (FNQ), Australia and their age of HBeAg loss. It was hoped that t...

Humans Hepatitis B e Antigens Native Hawaiian or Other Pacific Islander Female Hepatitis B, Chronic +12 autres

Kinetics of serum O-glycosylated M-hepatitis B surface antigen with hepatocellular carcinoma history and nucleos(t)ide analogue therapy in hepatitis B patients.

09 2023
DOI: 10.1111/jvh.13869 PMID: 37363934

A newly developed O-glycosylated M-hepatitis B surface antigen (HBsAgGi) measurement system can detect hepatitis B surface antigen (HBsAg) associated with infectious particles. We investigated the ass...

Humans Hepatitis B Surface Antigens Carcinoma, Hepatocellular Hepatitis B, Chronic Antiviral Agents +7 autres

Characteristics analysis of hepatitis B core-related antigen in children with hepatitis B e antigen-positive chronic viral hepatitis B infection.

28 Jun 2024
DOI: 10.1097/MEG.0000000000002812 PMID: 38973529

The objective of antiviral therapy for chronic viral hepatitis B infection (CHB) is to achieve a functional cure. An important viral marker in the serum of patients with CHB is the serum hepatitis B c... A single-center retrospective study was conducted involving 79 children with CHB, aged between 0 and 16 years. All the children were treated with interferon [or combined nucleos(t)ide analogs] for 48 ... HBsAg seroclearance was observed in 28 out of 79 patients and hepatitis B e antigen seroconversion without HBsAg seroclearance was observed in 14 out of 79 patients following the conclusion of the tre... A decrease in serum HBcrAg levels in children with hepatitis B serves as a prognostic indicator....

Human immunodeficiency virus coinfection differentially impacts hepatitis B virus viral markers based on hepatitis Be antigen status in patients with suppressed viremia.

08 2023
DOI: 10.1111/jvh.13857 PMID: 37278302

Hepatitis B virus (HBV) RNA and hepatitis B core-related antigen (HBcrAg), reflecting transcriptional activity of covalently closed circular DNA, are gaining traction as important markers to assess vi...

Adult Humans Hepatitis B virus Hepatitis B e Antigens Hepatitis B, Chronic +12 autres

The efficacy and safety of pegylated interferon α-2b-based immunotherapy for inactive hepatitis B surface antigen carriers.

01 10 2023
DOI: 10.1097/MEG.0000000000002627 PMID: 37577817

Pegylated interferon α-2b (PegIFNα-2b) therapy can help inactive hepatitis B surface antigen (HBsAg) carriers (IHCs) achieve clinical cure. To explore and compare the efficacy, safety, and relevant in... This exploratory, prospective, single-center, randomized controlled trial enrolled 40 IHCs who were randomized into group A (PegIFNα-2b treatment for 68 weeks) and group B (two cycles of PegIFNα-2b tr... At week 68, the HBsAg loss rates were 45.45% [full analysis set (FAS)] and 46.67% [per-protocol set (PPS)]. There was no statistically significant difference in HBsAg loss rate between groups A and B ... Treatment of IHCs with PegIFNα-2b-based therapy could result in a high HBsAg loss rate. The HBsAg loss rate of combined immunotherapy was similar to that of PegIFNα-2b monotherapy, and the safety was ... NCT05451420....

Humans Adult Hepatitis B Surface Antigens Antiviral Agents Prospective Studies +8 autres

Hepatitis B viral replication markers and hepatic fibrosis in untreated chronic hepatitis B virus infection with and without HIV coinfection in Zambia.

01 11 2023
DOI: 10.1097/QAD.0000000000003659 PMID: 37467044

To inform novel therapies, a more nuanced understanding of HIV's impact on hepatitis B virus (HBV) natural history is needed, particularly in high burden countries.... In Lusaka, Zambia, we compared prospectively recruited adults (18+ years) with chronic HBV infection, with and without HIV. We excluded those with prior antiviral treatment experience or HBV diagnosis... Among 713 adults analyzed, median age was 33 years, 63% were male, and 433 had HBV/HIV coinfection. Median CD4 + count was 200 cells/μl. HBV DNA was greater than 2000 IU/ml for 311 (51.0%) and 227 (32... HIV's impact on HBV natural history likely depends on the degree and duration of immune suppression. There is strong rationale to monitor HBV DNA in people with HBV/HIV coinfection and immune suppress...

Adult Humans Male Female Hepatitis B, Chronic +9 autres