Recurrent Hypoglycemia Due to a High Titer of Insulin Antibody in Response to Exogenous Insulin Administration in Two Cases of Type 1 Diabetes.


Journal

Internal medicine (Tokyo, Japan)
ISSN: 1349-7235
Titre abrégé: Intern Med
Pays: Japan
ID NLM: 9204241

Informations de publication

Date de publication:
01 Mar 2022
Historique:
pubmed: 3 9 2021
medline: 3 3 2022
entrez: 2 9 2021
Statut: ppublish

Résumé

In the first case, a 60-year-old man who was using continuous subcutaneous insulin infusion (CSII), developed recurrent hypoglycemia due to insulin antibodies. This is the first report of such a case using CSII. In the second case, a 70-year-old man was follow-up case who developed hypoglycemia while using human insulin. In both cases, the hypoglycemia subsided after switching to multiple daily insulin injection and/or insulin preparation. The results of Scatchard analyses of the two cases were similar to those of cases of insulin autoimmune syndrome (IAS) that improved after recovery from hypoglycemia.The clinical characteristics and Scatchard analysis data were essentially the same as those for IAS, except for the presence of insulin administration.

Identifiants

pubmed: 34471020
doi: 10.2169/internalmedicine.7647-21
pmc: PMC8943391
doi:

Substances chimiques

Glycated Hemoglobin A 0
Hypoglycemic Agents 0
Insulin 0
Insulin Antibodies 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

687-695

Références

Nihon Naika Gakkai Zasshi. 2013 Nov 10;102(11):2976-9
pubmed: 24450135
Diabetes Res Clin Pract. 2011 Nov;94(2):e53-4; discussion e55
pubmed: 21724289
Pediatr Diabetes. 2011 Mar;12(2):75-7
pubmed: 21352424
Intern Med. 2006;45(21):1225-9
pubmed: 17139123
Diabetes Res Clin Pract. 1994 Jan;22(2-3):89-94
pubmed: 8200300
N Engl J Med. 1960 May 12;262:978-9
pubmed: 14400231
Diabetes Care. 2002 Jun;25(6):995-1001
pubmed: 12032105
BMC Endocr Disord. 2019 Jan 8;19(1):5
pubmed: 30621663
Diabetes Res Clin Pract. 2008 Feb;79(2):220-9
pubmed: 17950950
Pediatr Diabetes. 2012 Feb;13(1):33-44
pubmed: 22128760
Diabetes Res Clin Pract. 2009 May;84(2):e21-3
pubmed: 19328577
J Med Case Rep. 2019 Mar 11;13(1):79
pubmed: 30853027
Nihon Naika Gakkai Zasshi. 2013 Feb 10;102(2):437-9
pubmed: 23767324
J Clin Endocrinol Metab. 2014 Sep;99(9):E1793-7
pubmed: 24971665
J Diabetes Investig. 2019 Nov;10(6):1447-1453
pubmed: 30970177
Diabetes Res Clin Pract. 2006 Jun;72(3):238-43
pubmed: 16439034
Endocr Rev. 2007 Oct;28(6):625-52
pubmed: 17785428
Acta Diabetol. 2010 Dec;47(4):325-30
pubmed: 20842389
Endocr J. 2016;63(2):187-91
pubmed: 26549210
Autoimmunity. 1994;19(4):279-84
pubmed: 7578855
Lancet. 1992 Feb 15;339(8790):393-4
pubmed: 1346661

Auteurs

Ryoichi Kawamura (R)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.

Satoshi Miyao (S)

Shiraishi Hospital Diabetes Center, Japan.

Hiroshi Onuma (H)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.
Department of Diabetes, Endocrine and Metabolic Disease, Tokyo Women's Medical University Yachiyo Medical Center, Japan.

Yasuko Uchigata (Y)

Tokyo Women's Medical University Medical Center East, Japan.

Eiji Kawasaki (E)

Department of Diabetes and Endocrinology, Shin-Koga Hospital, Japan.

Jun Ohashi (J)

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Japan.

Sanshiro Shiraishi (S)

Shiraishi Hospital Diabetes Center, Japan.

Wataru Nishida (W)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.

Maki Yokomoto-Umakoshi (M)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.

Yasunori Takata (Y)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.

Haruhiko Osawa (H)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.

Hideichi Makino (H)

Department of Diabetes and Molecular Genetics, Ehime University Graduate School of Medicine, Japan.
Shiraishi Hospital Diabetes Center, Japan.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH