Heart Weight Is an Independent Factor Associated With, But Is a Poor Predictor for, Sudden Cardiac Death.


Journal

The American journal of forensic medicine and pathology
ISSN: 1533-404X
Titre abrégé: Am J Forensic Med Pathol
Pays: United States
ID NLM: 8108948

Informations de publication

Date de publication:
01 Mar 2022
Historique:
pubmed: 7 9 2021
medline: 8 2 2022
entrez: 6 9 2021
Statut: ppublish

Résumé

An enlarged heart can cause electrical instability and impaired contractility, leading to fatal arrhythmia and acute heart failure, and is associated with sudden cardiac death. However, there is limited postmortem evidence on whether heart weight is an independent factor associated with sudden cardiac death. This 18-month retrospective study examined 108 adult heart weights in which all the hearts were weighed after dissection, blood and blood clots removed, rinsed in water, and pat dried. The multivariate logistic regression analysis showed heart weight was an independent factor associated with sudden cardiac death. However, after normalization, the heart weight was a poor predictor of sudden cardiac death with an area under the curve less than 0.7 in the plotted receiver operating characteristic curve.

Identifiants

pubmed: 34483235
doi: 10.1097/PAF.0000000000000711
pii: 00000433-202203000-00005
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

18-22

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors report no conflict of interest.

Références

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Auteurs

Jack Garland (J)

From the Forensic and Analytical Science Service, NSW Health Pathology, New South Wales, Australia.

Kilak Kesha (K)

Northern Forensic Pathology Service of New Zealand, Auckland, New Zealand.

Charley Glenn (C)

Northern Forensic Pathology Service of New Zealand, Auckland, New Zealand.

Simon Stables (S)

Northern Forensic Pathology Service of New Zealand, Auckland, New Zealand.

Benjamin Ondruschka (B)

Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Larissa Lohner (L)

Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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