Human Adenovirus Type 7 Infections in Hubei, China During 2018-2019: Epidemic Features and Genetic Characterization of the Detected Viruses.
children
epidemic features
genome characterization
hemophagocytic lymphohistiocystosis (HLH)
human adenovirus type 7 (HAdV-7)
Journal
Frontiers in cellular and infection microbiology
ISSN: 2235-2988
Titre abrégé: Front Cell Infect Microbiol
Pays: Switzerland
ID NLM: 101585359
Informations de publication
Date de publication:
2021
2021
Historique:
received:
02
04
2021
accepted:
29
07
2021
entrez:
7
9
2021
pubmed:
8
9
2021
medline:
21
10
2021
Statut:
epublish
Résumé
Human adenoviruses (HAdVs) type 7 can cause severe respiratory disease. During the period between December 2018 and August 2019, HAdV-7 infection was identified in 129 patients in Wuhan Children's Hospital, Hubei Province, China. Samples were collected from hospitalized children and metagenomic sequencing was applied to detect the HAdV infections. Hemophagocytic lymphohistiocystosis (HLH) related to HAdV infections was observed in some patients clinically and patients were divided into two groups based on this to test the differences among clinical indicators. Genome variation,
Identifiants
pubmed: 34490137
doi: 10.3389/fcimb.2021.684606
pmc: PMC8417316
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
684606Informations de copyright
Copyright © 2021 Li, Wang, Zhang, Huang, Du, Xu, Chen, Yan, Chen, Lu and Liu.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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