Reactivation of herpes simplex keratitis following vaccination for COVID-19.
anterior chamber
ophthalmology
public health
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
07 Sep 2021
07 Sep 2021
Historique:
entrez:
8
9
2021
pubmed:
9
9
2021
medline:
10
9
2021
Statut:
epublish
Résumé
An 82-year-old man with a history of herpes simplex keratitis 40 years previously presented with recurrence, 1 day following vaccination for novel COVID-19. His condition worsened despite topical treatment with ganciclovir gel. A diagnosis of herpetic stromal keratitis was made, requiring systemic aciclovir, topical prednisolone, moxifloxacin and atropine, and oral doxycycline. He improved clinically on treatment, with some residual corneal scarring. Visual acuity improved from 6/36 corrected at presentation, to 6/24 following treatment. Clearly, public and personal health benefits from vaccination are hugely important and we would not suggest avoiding vaccination in such patients. It is, however, important for ophthalmic providers to be aware of the rare potential for reactivation of herpetic eye disease following vaccination to enable prompt diagnosis and treatment.
Identifiants
pubmed: 34493563
pii: 14/9/e245792
doi: 10.1136/bcr-2021-245792
pmc: PMC8424829
pii:
doi:
Substances chimiques
Antiviral Agents
0
Prednisolone
9PHQ9Y1OLM
Acyclovir
X4HES1O11F
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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