Prediction of the severity of colorectal lesion by fecal hemoglobin concentration observed during previous test in the French screening program.
Colorectal cancer screening
Colorectal lesion severity
Fecal hemoglobin concentration
Fecal immunochemical test
Journal
World journal of gastroenterology
ISSN: 2219-2840
Titre abrégé: World J Gastroenterol
Pays: United States
ID NLM: 100883448
Informations de publication
Date de publication:
21 Aug 2021
21 Aug 2021
Historique:
received:
12
02
2021
revised:
03
05
2021
accepted:
20
07
2021
entrez:
9
9
2021
pubmed:
10
9
2021
medline:
11
9
2021
Statut:
ppublish
Résumé
The rate of positive tests using fecal immunochemical test (FIT) does not decrease with subsequent campaigns, but the positive predictive value of advanced neoplasia significantly decreases in subsequent campaign after a first negative test. A relationship between the fecal hemoglobin concentration (Fhb) and the opportunity to detect a colorectal cancer in subsequent campaign has been shown. To predict the severity of colorectal lesions based on Fhb measured during previous colorectal cancer screening campaign. This etiological study included 293750 patients aged 50-74, living in Auvergne-Rhône-Alpes (France). These patients completed at least two FIT [test The test The study showed that higher Fhb
Sections du résumé
BACKGROUND
BACKGROUND
The rate of positive tests using fecal immunochemical test (FIT) does not decrease with subsequent campaigns, but the positive predictive value of advanced neoplasia significantly decreases in subsequent campaign after a first negative test. A relationship between the fecal hemoglobin concentration (Fhb) and the opportunity to detect a colorectal cancer in subsequent campaign has been shown.
AIM
OBJECTIVE
To predict the severity of colorectal lesions based on Fhb measured during previous colorectal cancer screening campaign.
METHODS
METHODS
This etiological study included 293750 patients aged 50-74, living in Auvergne-Rhône-Alpes (France). These patients completed at least two FIT [test
RESULTS
RESULTS
The test
CONCLUSION
CONCLUSIONS
The study showed that higher Fhb
Identifiants
pubmed: 34497450
doi: 10.3748/wjg.v27.i31.5272
pmc: PMC8384754
doi:
Substances chimiques
Hemoglobins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
5272-5287Informations de copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
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