Pharmacology of TRPC Channels and Its Potential in Cardiovascular and Metabolic Medicine.

Cardiovascular System / metabolism Humans Transient Receptor Potential Channels / metabolism
TRP channel cardiovascular cryo-EM ion channel metabolic small-molecule modulators

Journal

Annual review of pharmacology and toxicology
ISSN: 1545-4304
Titre abrégé: Annu Rev Pharmacol Toxicol
Pays: United States
ID NLM: 7607088

Informations de publication

Date de publication:
06 01 2022
Historique:
pubmed: 10 9 2021
medline: 22 3 2022
entrez: 9 9 2021
Statut: ppublish

Résumé

Transient receptor potential canonical (TRPC) proteins assemble to form homo- or heterotetrameric, nonselective cation channels permeable to K

Identifiants

DOI: 10.1146/annurev-pharmtox-030121-122314 PMID: 34499525
pubmed: 34499525
doi: 10.1146/annurev-pharmtox-030121-122314
doi:

Substances chimiques

Transient Receptor Potential Channels 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

427-446

Subventions

Organisme : Medical Research Council
ID : MC_PC_18053
Pays : United Kingdom
Organisme : British Heart Foundation
ID : RG/17/11/33042
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 110044/Z/15/Z
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
Pays : United Kingdom

Auteurs

Robin S Bon (RS)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, United Kingdom; email: r.bon@leeds.ac.uk.

David J Wright (DJ)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, United Kingdom; email: r.bon@leeds.ac.uk.

David J Beech (DJ)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, United Kingdom; email: r.bon@leeds.ac.uk.

Piruthivi Sukumar (P)

Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, United Kingdom; email: r.bon@leeds.ac.uk.

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Classifications MeSH

questionsmedicales.fr › Système cardiovasculaire › Pharmacology of TRPC Channels and Its...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Pharmacology of TRPC Channels and Its...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Canaux cationiques TRP › Pharmacology of TRPC Channels and Its...