Preliminary Insight of Pyrrolylated-Chalcones as New Anti-Methicillin-Resistant

Anti-Bacterial Agents / chemistry Chalcones / chemistry Dose-Response Relationship, Drug Methicillin-Resistant Staphylococcus aureus / drug effects Microbial Sensitivity Tests Molecular Structure Pyrroles / chemistry Structure-Activity Relationship
anti-MRSA molecular docking pyrrolylated-chalcones synthesis zebrafish toxicity

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
01 Sep 2021
Historique:
received: 28 07 2021
revised: 27 08 2021
accepted: 28 08 2021
entrez: 10 9 2021
pubmed: 11 9 2021
medline: 10 11 2021
Statut: epublish

Résumé

Bacterial infections are regarded as one of the leading causes of fatal morbidity and death in patients infected with diseases. The ability of microorganisms, particularly methicillin-resistant

Identifiants

DOI: 10.3390/molecules26175314 PMID: 34500755 PMC: PMC8434082
pubmed: 34500755
pii: molecules26175314
doi: 10.3390/molecules26175314
pmc: PMC8434082
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Chalcones 0
Pyrroles 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Universiti Putra Malaysia
ID : GP-IPS/2018/9618500
Organisme : National Research Foundation of Korea
ID : 2018M3A9B8021980

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

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Auteurs

Mohanapriya Gunasekharan (M)

Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Tae-Ik Choi (TI)

Department of Biology, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea.

Yaya Rukayadi (Y)

Natural Medicines and Product Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
ORCID: 0000-0001-7807-4462

Muhammad Alif Mohammad Latif (MA)

Centre of Foundation Studies for Agricultural Science, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
ORCID: 0000-0002-3345-0265

Thiruventhan Karunakaran (T)

Centre for Drug Research, Universiti Sains Malaysia, Gelugor 11800, Pulau Pinang, Malaysia.
ORCID: 0000-0003-4470-2656

Siti Munirah Mohd Faudzi (SM)

Department of Chemistry, Faculty of Science, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.
Natural Medicines and Product Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Selangor, Malaysia.

Cheol-Hee Kim (CH)

Department of Biology, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea.
ORCID: 0000-0002-3019-0699

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Chalcones › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus › Staphylococcus aureus résistant à la méticilline › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Pyrroles › Preliminary Insight of Pyrrolylated-Chalcones...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Preliminary Insight of Pyrrolylated-Chalcones...