Chemo-Preventive Action of Resveratrol: Suppression of p53-A Molecular Targeting Approach.
cancer prevention
cardio protection
clinical trials
molecular signals
natural compound
p53
polyphenol
red wine
resveratrol
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
02 Sep 2021
02 Sep 2021
Historique:
received:
26
07
2021
revised:
24
08
2021
accepted:
30
08
2021
entrez:
10
9
2021
pubmed:
11
9
2021
medline:
11
11
2021
Statut:
epublish
Résumé
Extensive experimental, clinical, and epidemiological evidence has explained and proven that products of natural origin are significantly important in preventing and/or ameliorating various disorders, including different types of cancer that researchers are extremely focused on. Among these studies on natural active substances, one can distinguish the emphasis on resveratrol and its properties, especially the potential anticancer role. Resveratrol is a natural product proven for its therapeutic activity, with remarkable anti-inflammatory properties. Various other benefits/actions have also been reported, such as cardioprotective, anti-ageing, antioxidant, etc. and its rapid digestion/absorption as well. This review aims to collect and present the latest published studies on resveratrol and its impact on cancer prevention, molecular signals (especially p53 protein participation), and its therapeutic prospects. The most recent information regarding the healing action of resveratrol is presented and concentrated to create an updated database focused on this topic presented above.
Identifiants
pubmed: 34500758
pii: molecules26175325
doi: 10.3390/molecules26175325
pmc: PMC8433711
pii:
doi:
Substances chimiques
Antineoplastic Agents, Phytogenic
0
Tumor Suppressor Protein p53
0
Resveratrol
Q369O8926L
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
BMC Cancer. 2013 Mar 22;13:147
pubmed: 23522185
Front Pharmacol. 2020 Dec 30;11:619024
pubmed: 33456444
Cancer Res. 1998 Dec 15;58(24):5707-12
pubmed: 9865727
Cancer Lett. 2008 Oct 8;269(2):243-61
pubmed: 18550275
Carcinogenesis. 1999 Feb;20(2):237-42
pubmed: 10069459
Cancer Prev Res (Phila). 2009 May;2(5):409-18
pubmed: 19401532
Mol Pharmacol. 1999 Oct;56(4):760-7
pubmed: 10496959
Pharm Res. 2010 Jun;27(6):979-88
pubmed: 20119749
PLoS One. 2012;7(11):e48746
pubmed: 23152798
Cytotherapy. 2011 Aug;13(7):802-13
pubmed: 21506889
Trends Mol Med. 2007 May;13(5):192-9
pubmed: 17383232
Nature. 2003 Sep 11;425(6954):191-6
pubmed: 12939617
Mutat Res. 2003 Feb-Mar;523-524:145-50
pubmed: 12628512
Nutrients. 2016 Jun 09;8(6):
pubmed: 27294953
J Cell Biochem. 2012 Aug;113(8):2586-96
pubmed: 22415970
PLoS One. 2014 Feb 26;9(2):e90131
pubmed: 24587240
Eur J Cancer Prev. 2005 Apr;14(2):139-42
pubmed: 15785317
Cardiovasc Res. 2000 Aug 18;47(3):549-55
pubmed: 10963727
J Steroid Biochem Mol Biol. 2004 Mar;88(3):223-34
pubmed: 15120416
Plant Foods Hum Nutr. 2010 Mar;65(1):57-63
pubmed: 20108046
Am J Clin Nutr. 2002 Oct;76(4):865-72
pubmed: 12324302
J Natl Cancer Inst. 1992 Dec 16;84(24):1887-96
pubmed: 1334153
Int J Cancer. 2015 Mar 1;136(5):E359-86
pubmed: 25220842
J Biol Chem. 2015 Dec 11;290(50):29769-80
pubmed: 26468275
Food Chem Toxicol. 2016 Nov;97:96-107
pubmed: 27591926
Cell. 2006 Dec 15;127(6):1109-22
pubmed: 17112576
Curr Protein Pept Sci. 2018;19(3):311-322
pubmed: 28079008
Int J Cardiol. 2017 Jan 15;227:66-82
pubmed: 27852009
Mol Nutr Food Res. 2014 Sep;58(9):1785-94
pubmed: 24975132
Cancer Prev Res (Phila). 2011 Sep;4(9):1419-25
pubmed: 21680702
Oncol Rep. 2013 May;29(5):1851-8
pubmed: 23446753
Free Radic Biol Med. 2006 Jul 15;41(2):318-25
pubmed: 16814113
Cancer Cell. 2016 Jan 11;29(1):90-103
pubmed: 26748848
Ann N Y Acad Sci. 2011 Jan;1215:48-59
pubmed: 21261641
Nat Rev Mol Cell Biol. 2007 Apr;8(4):275-83
pubmed: 17380161
Cancer Sci. 2012 Jun;103(6):1090-8
pubmed: 22417066
ACS Nano. 2011 Aug 23;5(8):6184-94
pubmed: 21728341
Clin Pharmacokinet. 2010 Jul;49(7):449-54
pubmed: 20528005
J Mol Biol. 2003 Oct 17;333(2):443-51
pubmed: 14529628
Biochim Biophys Acta Proteins Proteom. 2017 May;1865(5):589-603
pubmed: 28238838
Cardiovasc Drug Rev. 2004 Fall;22(3):169-88
pubmed: 15492766
J Med Food. 2008 Dec;11(4):773-83
pubmed: 19053873
Curr Pharm Des. 2012;18(1):27-33
pubmed: 22211686
Cancer Res. 2010 Oct 1;70(19):7392-9
pubmed: 20841478
Nat Rev Cancer. 2009 Oct;9(10):714-23
pubmed: 19730431
Cancer Manag Res. 2009 Apr 03;1:25-37
pubmed: 21188121
Drug Metab Dispos. 2007 May;35(5):699-703
pubmed: 17287390
Pharmacol Res. 2012 Nov;66(5):375-82
pubmed: 22906730
Curr Pharm Des. 2021;27(3):345-356
pubmed: 33138754
Life Sci. 2002 Nov 22;72(1):23-34
pubmed: 12409142
Front Plant Sci. 2012 Jan 26;3:9
pubmed: 22639636
Food Funct. 2014 Apr;5(4):663-70
pubmed: 24569685
Cancer Sci. 2009 Sep;100(9):1655-62
pubmed: 19496785
J Clin Endocrinol Metab. 2017 May 1;102(5):1642-1651
pubmed: 28182820
J Biol Chem. 2012 Aug 10;287(33):28152-62
pubmed: 22715097
Am J Epidemiol. 1989 Nov;130(5):883-94
pubmed: 2554725
Ann N Y Acad Sci. 2011 Jan;1215:144-9
pubmed: 21261653
Ann N Y Acad Sci. 2011 Jan;1215:150-60
pubmed: 21261654
J Agric Food Chem. 2011 May 11;59(9):4979-86
pubmed: 21401048
Br J Haematol. 2011 Jul;154(1):32-75
pubmed: 21569004
Mol Nutr Food Res. 2005 May;49(5):462-71
pubmed: 15786518
Mol Nutr Food Res. 2010 Nov;54(11):1574-84
pubmed: 20521268
Pharmacol Res. 2006 Jan;53(1):6-15
pubmed: 16169743
J Transl Med. 2013 Oct 20;11:264
pubmed: 24138806
Phytother Res. 2008 Oct;22(10):1367-71
pubmed: 18688788
Nat Rev Cancer. 2004 Oct;4(10):793-805
pubmed: 15510160
Ann N Y Acad Sci. 2011 Jan;1215:161-9
pubmed: 21261655
J Biol Chem. 2010 Jan 22;285(4):2857-66
pubmed: 19933157
Front Pharmacol. 2013 May 07;4:57
pubmed: 23675348
Mol Nutr Food Res. 2013 Jul;57(7):1170-81
pubmed: 23495229
Cancer Prev Res (Phila). 2010 Sep;3(9):1168-75
pubmed: 20716633
Science. 1998 Nov 20;282(5393):1497-501
pubmed: 9822382
Arch Biochem Biophys. 2009 Jun 15;486(2):95-102
pubmed: 19514131
Steroids. 2007 Feb;72(2):165-70
pubmed: 17166537
Nutrients. 2016 Sep 09;8(9):
pubmed: 27618095
Oncotarget. 2014 Dec 30;5(24):12891-907
pubmed: 25436977
Molecules. 2017 Jun 18;22(6):
pubmed: 28629161
Rom J Morphol Embryol. 2015;56(3):1103-9
pubmed: 26662146
PLoS One. 2013 May 27;8(5):e64378
pubmed: 23724044
J Exp Clin Cancer Res. 2017 Jan 26;36(1):19
pubmed: 28126034
J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Apr 1;848(2):182-7
pubmed: 17097357
Biochem Biophys Res Commun. 2011 Jul 15;410(4):707-13
pubmed: 21557933
Food Funct. 2012 Jul;3(7):745-52
pubmed: 22572890
Int J Cancer. 2009 Jun 15;124(12):2780-8
pubmed: 19334045
Strahlenther Onkol. 2014 Jan;190(1):75-80
pubmed: 24196280
Trends Biochem Sci. 2014 Jun;39(6):260-7
pubmed: 24775734
Carcinogenesis. 2007 Sep;28(9):2002-7
pubmed: 17638921
Molecules. 2014 Jun 11;19(6):7850-68
pubmed: 24962390
Nature. 2006 Nov 16;444(7117):337-42
pubmed: 17086191
BMC Cancer. 2011 Mar 19;11:99
pubmed: 21418583
Aging (Albany NY). 2017 Feb 26;9(2):508-523
pubmed: 28238967
Int J Oncol. 2013 Dec;43(6):1999-2006
pubmed: 24141489
Nat Struct Biol. 2000 Apr;7(4):312-21
pubmed: 10742177
Eur J Med Chem. 2010 Jul;45(7):2972-80
pubmed: 20395019
Cell Death Differ. 2000 Sep;7(9):834-42
pubmed: 11042678
Cancer Res. 2001 Jun 15;61(12):4731-9
pubmed: 11406544
Cancer Res. 2010 Nov 15;70(22):9003-11
pubmed: 20935227
Sci Total Environ. 2019 Jul 1;672:129-140
pubmed: 30954811
Int J Cancer. 2011 Dec 1;129(11):2732-43
pubmed: 21225623
Atherosclerosis. 2006 Sep;188(1):77-83
pubmed: 16310197
Am J Clin Nutr. 2010 Jun;91(6):1590-7
pubmed: 20357044
J Clin Epidemiol. 2021 Jun;134:178-189
pubmed: 33789819
Ann N Y Acad Sci. 2015 Aug;1348(1):134-40
pubmed: 26173478
Drug Metab Dispos. 2004 Dec;32(12):1377-82
pubmed: 15333514
Phytochem Rev. 2010 Sep;9(3):357-378
pubmed: 20835385
Br J Cancer. 2004 Oct 4;91(7):1380-3
pubmed: 15316568
Biochem Biophys Res Commun. 2013 Jan 18;430(3):963-8
pubmed: 23261448
Clin Gastroenterol Hepatol. 2014 Dec;12(12):2092-103.e1-6
pubmed: 24582567
QJM. 1997 Nov;90(11):653-6
pubmed: 9474345
Heart. 2004 Jan;90(1):107-11
pubmed: 14676260
Can J Surg. 2007 Apr;50(2):137-42
pubmed: 17550719
Nat Genet. 2014 Mar;46(3):234-44
pubmed: 24509480
Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1246-52
pubmed: 17548692
J Am Chem Soc. 2009 Jul 15;131(27):9516-21
pubmed: 19583433
J Med Food. 2010 Dec;13(6):1415-23
pubmed: 20946021
Curr Med Chem. 2011;18(8):1100-21
pubmed: 21291372
Biochem Pharmacol. 2009 Apr 15;77(8):1337-47
pubmed: 19426672
Ann Hematol. 2011 Feb;90(2):173-83
pubmed: 20714724
Cancer Res. 2001 Feb 15;61(4):1604-10
pubmed: 11245472
J Gerontol A Biol Sci Med Sci. 2012 Feb;67(2):158-67
pubmed: 21746739
Cell Mol Life Sci. 2019 May;76(10):1947-1966
pubmed: 30879091
Cancer Prev Res (Phila). 2010 Apr;3(4):549-59
pubmed: 20332304
J Clin Epidemiol. 2021 Jun;134:103-112
pubmed: 33577987
Curr Drug Targets. 2006 Apr;7(4):423-42
pubmed: 16611030
Front Nutr. 2016 Apr 12;3:8
pubmed: 27148534
J Control Release. 2012 Mar 10;158(2):182-93
pubmed: 21978644
Ann N Y Acad Sci. 2011 Jan;1215:1-8
pubmed: 21261635
Neurotoxicology. 2009 Nov;30(6):986-95
pubmed: 19744518
Mol Nutr Food Res. 2011 Aug;55(8):1129-41
pubmed: 21688389
Anticancer Res. 2001 Jul-Aug;21(4B):2895-900
pubmed: 11712783
Nutr Metab Cardiovasc Dis. 2011 Nov;21(11):851-6
pubmed: 20674311
Biochem Soc Trans. 2007 Nov;35(Pt 5):1156-60
pubmed: 17956300
Xenobiotica. 2000 Jun;30(6):609-17
pubmed: 10923862
Am J Clin Nutr. 2013 Feb;97(2):295-309
pubmed: 23283496
J Clin Pharmacol. 2009 Dec;49(12):1477-82
pubmed: 19797536
PLoS One. 2011;6(6):e19881
pubmed: 21698226
Anticancer Res. 2014 Oct;34(10):5363-74
pubmed: 25275030
Biochimie. 2012 Feb;94(2):269-76
pubmed: 22133615
J Mol Signal. 2007 Aug 24;2:7
pubmed: 17718901
Cancer Res. 2007 Dec 15;67(24):12007-17
pubmed: 18089832
Nature. 2000 Nov 16;408(6810):307-10
pubmed: 11099028
Science. 1997 Jan 10;275(5297):218-20
pubmed: 8985016
Nutrients. 2017 Jul 21;9(7):
pubmed: 28754004
Ann N Y Acad Sci. 2015 Aug;1348(1):161-70
pubmed: 26315294
J Clin Endocrinol Metab. 2002 Mar;87(3):1223-32
pubmed: 11889192
Sci Rep. 2016 Sep 07;6:32535
pubmed: 27600721
Ann N Y Acad Sci. 2013 Jul;1290:1-11
pubmed: 23855460
Oxid Med Cell Longev. 2015;2015:837042
pubmed: 26221416
Radiat Oncol. 2011 Oct 26;6:144
pubmed: 22029423
Ann N Y Acad Sci. 2015 Aug;1348(1):20-31
pubmed: 26109073
Cancer Causes Control. 1991 Mar;2(2):85-94
pubmed: 1873441
Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2634-E2643
pubmed: 28292898
J Pathol. 2009 Sep;219(1):3-15
pubmed: 19562738
Mol Nutr Food Res. 2009 May;53 Suppl 1:S7-15
pubmed: 19194969