Treatment of Eosinophilic Esophagitis: Diet or Medication?

Adult Biological Products Child Diet Eosinophilic Esophagitis / drug therapy Glucocorticoids Humans Proton Pump Inhibitors / therapeutic use
Biologic Corticosteroid Diet Eosinophil Esophagus Fibrosis Food antigen Proton pump inhibitor Remodeling

Journal

The journal of allergy and clinical immunology. In practice
ISSN: 2213-2201
Titre abrégé: J Allergy Clin Immunol Pract
Pays: United States
ID NLM: 101597220

Informations de publication

Date de publication:
09 2021
Historique:
received: 29 06 2021
revised: 22 07 2021
accepted: 22 07 2021
entrez: 11 9 2021
pubmed: 12 9 2021
medline: 28 10 2021
Statut: ppublish

Résumé

Eosinophilic esophagitis (EoE) is an antigen-triggered chronic disease of increasing prevalence in children and adults. Untreated or therapy-resistant EoE leads to complications of esophageal food impactions and luminal narrowing. The past decade has seen a number of new clinical trials for EoE therapies including elimination diets, proton pump inhibitors, swallowed topical corticosteroids, and biologics. In this review, we comment on the current state of the art for dietary and pharmacologic management of EoE and the need for future clinical trials to help tailor therapies to individual patients with this chronic disease.

Identifiants

DOI: 10.1016/j.jaip.2021.07.029 PMID: 34507706
pubmed: 34507706
pii: S2213-2198(21)00833-3
doi: 10.1016/j.jaip.2021.07.029
pii:
doi:

Substances chimiques

Biological Products 0
Glucocorticoids 0
Proton Pump Inhibitors 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3249-3256

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI092135
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI140133
Pays : United States
Organisme : NIAID NIH HHS
ID : K24 AI135034
Pays : United States
Organisme : NIAID NIH HHS
ID : U54 AI117804
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES031940
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK114457
Pays : United States
Organisme : NIAID NIH HHS
ID : R21 AI154353
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Auteurs

Mirna Chehade (M)

Department of Pediatrics, Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: mirna.chehade@mssm.edu.

Seema S Aceves (SS)

Division of Allergy and Immunology, Department of Pediatrics, University of California, San Diego, Rady Children's Hospital, San Diego, Calif.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Personnes › Tranches d'âge › Enfant › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Phénomènes physiologiques › Alimentation et nutrition › Phénomènes physiologiques nutritionnels › Régime alimentaire › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Oesophagite à éosinophiles › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Glucocorticoïdes › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Treatment of Eosinophilic Esophagitis: Diet or...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de la pompe à protons › Treatment of Eosinophilic Esophagitis: Diet or...