Feasibility of late gadolinium enhancement (LGE) in ischemic cardiomyopathy using 2D-multisegment LGE combined with artificial intelligence reconstruction deep learning noise reduction algorithm.

Artificial intelligence Deep learning reconstruction Image noise Ischemic cardiomyopathy Late gadolinium enhancement

Journal

International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291

Informations de publication

Date de publication:
15 Nov 2021
Historique:
received: 26 04 2021
revised: 05 07 2021
accepted: 07 09 2021
pubmed: 14 9 2021
medline: 21 10 2021
entrez: 13 9 2021
Statut: ppublish

Résumé

Despite the low spatial resolution of 2D-multisegment late gadolinium enhancement (2D-MSLGE) sequences, it may be useful in uncooperative patients instead of standard 2D single segmented inversion recovery gradient echo late gadolinium enhancement sequences (2D-SSLGE). The aim of the study is to assess the feasibility and comparison of 2D-MSLGE reconstructed with artificial intelligence reconstruction deep learning noise reduction (NR) algorithm compared to standard 2D-SSLGE in consecutive patients with ischemic cardiomyopathy (ICM). Fifty-seven patients with known ICM referred for a clinically indicated CMR were enrolled in this study. 2D-MSLGE were reconstructed using a growing level of NR (0%,25%,50%,75%and 100%). Subjective image quality, signal to noise ratio (SNR) and contrast to noise ratio (CNR) were evaluated in each dataset and compared to standard 2D-SSLGE. Moreover, diagnostic accuracy, LGE mass and scan time were compared between 2D-MSLGE with NR and 2D-SSLGE. The application of NR reconstruction ≥50% to 2D-MSLGE provided better subjective image quality, CNR and SNR compared to 2D-SSLGE (p < 0.01). The best compromise in terms of subjective and objective image quality was observed for values of 2D-MSLGE 75%, while no differences were found in terms of LGE quantification between 2D-MSLGE versus 2D-SSLGE, regardless the NR applied. The sensitivity, specificity, negative predictive value, positive predictive value and accuracy of 2D-MSLGE NR 75% were 87.77%,96.27%,96.13%,88.16% and 94.22%, respectively. Time of acquisition of 2D-MSLGE was significantly shorter compared to 2D-SSLGE (p < 0.01). When compared to standard 2D-SSLGE, the application of NR reconstruction to 2D-MSLGE provides superior image quality with similar diagnostic accuracy.

Sections du résumé

BACKGROUND BACKGROUND
Despite the low spatial resolution of 2D-multisegment late gadolinium enhancement (2D-MSLGE) sequences, it may be useful in uncooperative patients instead of standard 2D single segmented inversion recovery gradient echo late gadolinium enhancement sequences (2D-SSLGE). The aim of the study is to assess the feasibility and comparison of 2D-MSLGE reconstructed with artificial intelligence reconstruction deep learning noise reduction (NR) algorithm compared to standard 2D-SSLGE in consecutive patients with ischemic cardiomyopathy (ICM).
METHODS METHODS
Fifty-seven patients with known ICM referred for a clinically indicated CMR were enrolled in this study. 2D-MSLGE were reconstructed using a growing level of NR (0%,25%,50%,75%and 100%). Subjective image quality, signal to noise ratio (SNR) and contrast to noise ratio (CNR) were evaluated in each dataset and compared to standard 2D-SSLGE. Moreover, diagnostic accuracy, LGE mass and scan time were compared between 2D-MSLGE with NR and 2D-SSLGE.
RESULTS RESULTS
The application of NR reconstruction ≥50% to 2D-MSLGE provided better subjective image quality, CNR and SNR compared to 2D-SSLGE (p < 0.01). The best compromise in terms of subjective and objective image quality was observed for values of 2D-MSLGE 75%, while no differences were found in terms of LGE quantification between 2D-MSLGE versus 2D-SSLGE, regardless the NR applied. The sensitivity, specificity, negative predictive value, positive predictive value and accuracy of 2D-MSLGE NR 75% were 87.77%,96.27%,96.13%,88.16% and 94.22%, respectively. Time of acquisition of 2D-MSLGE was significantly shorter compared to 2D-SSLGE (p < 0.01).
CONCLUSION CONCLUSIONS
When compared to standard 2D-SSLGE, the application of NR reconstruction to 2D-MSLGE provides superior image quality with similar diagnostic accuracy.

Identifiants

pubmed: 34517017
pii: S0167-5273(21)01335-8
doi: 10.1016/j.ijcard.2021.09.012
pii:
doi:

Substances chimiques

Contrast Media 0
Gadolinium AU0V1LM3JT

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

164-170

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Giuseppe Muscogiuri (G)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Chiara Martini (C)

Diagnostic Department, Azienda Ospedaliera-Universitaria di Parma, Parma, Italy.

Marco Gatti (M)

Department of Surgical Sciences, Radiology Institute, University of Turin, Turin, Italy.

Serena Dell'Aversana (S)

Department of Radiology, S. Maria delle Grazie Hospital, Pozzuoli, Italy.

Francesca Ricci (F)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Marco Guglielmo (M)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Andrea Baggiano (A)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Laura Fusini (L)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Aurora Bracciani (A)

Institute of Radiology, Department of Medicine, University of Udine, Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy.

Stefano Scafuri (S)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Daniele Andreini (D)

Centro Cardiologico Monzino, IRCCS, Milan, Italy; Department of Cardiovascular Sciences and Community Health, University of Milan, Italy.

Saima Mushtaq (S)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Edoardo Conte (E)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Paola Gripari (P)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Andrea Daniele Annoni (AD)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Alberto Formenti (A)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Maria Elisabetta Mancini (ME)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Lorenzo Bonfanti (L)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Andrea Igoren Guaricci (AI)

Institute of Cardiovascular Disease, Department of Emergency and Organ Transplantation, University Hospital "Policlinico Consorziale" of Bari, Bari, Italy.

Martin A Janich (MA)

General Electric Healthcare, Munich, Germany.

Mark G Rabbat (MG)

Loyola University of Chicago, Chicago, IL, United States of America; Edward Hines Jr. VA Hospital, Hines, IL, United States of America.

Giulio Pompilio (G)

Centro Cardiologico Monzino, IRCCS, Milan, Italy; Department of Cardiovascular Sciences and Community Health, University of Milan, Italy.

Mauro Pepi (M)

Centro Cardiologico Monzino, IRCCS, Milan, Italy.

Gianluca Pontone (G)

Centro Cardiologico Monzino, IRCCS, Milan, Italy. Electronic address: gianluca.pontone@ccfm.it.

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Classifications MeSH