Unexpected Reactions of α,β-Unsaturated Fatty Acids Provide Insight into the Mechanisms of CYP152 Peroxygenases.


Journal

Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543

Informations de publication

Date de publication:
08 11 2021
Historique:
revised: 06 09 2021
received: 18 08 2021
pubmed: 16 9 2021
medline: 15 12 2021
entrez: 15 9 2021
Statut: ppublish

Résumé

CYP152 peroxygenases catalyze decarboxylation and hydroxylation of fatty acids using H

Identifiants

pubmed: 34523786
doi: 10.1002/anie.202111163
doi:

Substances chimiques

Fatty Acids, Unsaturated 0
Cytochrome P-450 Enzyme System 9035-51-2
Hydrogen Peroxide BBX060AN9V
Mixed Function Oxygenases EC 1.-
fatty acid alpha-hydroxylase EC 1.-
Peroxidases EC 1.11.1.-
cytochrome P-450 CYP152A1 (Bacillus subtilis) EC 1.14.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

24694-24701

Subventions

Organisme : the National Key Research and Development Program of China
ID : 2019YFA0905100
Organisme : the National Key Research and Development Program of China
ID : 2019YFA0706900
Organisme : National Natural Science Foundation of China
ID : 32025001
Organisme : National Natural Science Foundation of China
ID : 22073077
Organisme : the Natural Science Foundation of Shandong Province, China
ID : ZR2019ZD20
Organisme : the Laboratory for Marine Drugs and Bioproducts of Pilot National Laboratory for Marine Science and Technology
ID : LMDBKF-2019-01
Organisme : Tianjin Synthetic Biotechnology Innovation Capability Improvement Project
ID : TSBICIP-KJGG-001

Informations de copyright

© 2021 Wiley-VCH GmbH.

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Auteurs

Yuanyuan Jiang (Y)

State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao, Shandong, 266237, China.
Shandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao, Shandong, 266101, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.

Wei Peng (W)

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.

Zhong Li (Z)

State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao, Shandong, 266237, China.
Shandong Provincial Key Laboratory of Synthetic Biology, CAS Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao, Shandong, 266101, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.

Cai You (C)

State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao, Shandong, 266237, China.

Yue Zhao (Y)

Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430071, China.

Dandan Tang (D)

State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao, Shandong, 266237, China.

Binju Wang (B)

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, China.

Shengying Li (S)

State Key Laboratory of Microbial Technology, Shandong University, No. 72 Binhai Road, Qingdao, Shandong, 266237, China.
Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong, 266237, China.

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