An HDAC8-selective fluorescent probe for imaging in living tumor cell lines and tissue slices.

Fluorescent Dyes

Journal

Organic & biomolecular chemistry
ISSN: 1477-0539
Titre abrégé: Org Biomol Chem
Pays: England
ID NLM: 101154995

Informations de publication

Date de publication:
06 10 2021
Historique:
pubmed: 17 9 2021
medline: 18 3 2022
entrez: 16 9 2021
Statut: epublish

Résumé

Histone deacetylase 8 (HDAC8) has been used as a therapeutic target for many cancers as it is highly expressed in neuroblastoma cells and breast cancer cells. HDAC8-selective fluorescent probes need to be urgently developed. Herein, two novel fluorescent probes, namely

Identifiants

DOI: 10.1039/d1ob01367j PMID: 34528053
pubmed: 34528053
doi: 10.1039/d1ob01367j
doi:

Substances chimiques

Fluorescent Dyes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

8352-8366

Auteurs

Yinyu Yan (Y)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

Chaoqun Huang (C)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

Yi Shu (Y)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

Hongmei Wen (H)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.
ORCID: 0000-0002-5345-604X

Chenxiao Shan (C)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

Xinzhi Wang (X)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

Jian Liu (J)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

Wei Li (W)

School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, PR China. wenhm@njucm.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › An HDAC8-selective fluorescent probe for...