On the foundation of thermal "Switching": The culture substrate governs the phase transition mechanism of thermoresponsive brushes and their performance in cell sheet fabrication.
Block copolymer adsorption
Cell sheet
Enzyme-free
Structure-property correlation
Volume phase transition temperature
Journal
Acta biomaterialia
ISSN: 1878-7568
Titre abrégé: Acta Biomater
Pays: England
ID NLM: 101233144
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
received:
23
06
2021
revised:
23
08
2021
accepted:
08
09
2021
pubmed:
17
9
2021
medline:
15
12
2021
entrez:
16
9
2021
Statut:
ppublish
Résumé
Thermally "switchable" poly(glycidyl ether) (PGE) brushes constitute effective coatings for the temperature-triggered harvest of confluent cell sheets. Based on a simple "grafting-to" approach, such coatings can be tethered to various applied plastic culture substrate materials. Herein, we elucidate the self-assembly of PGE brushes with tunable grafting densities up to 0.12 and 0.22 chains nm
Identifiants
pubmed: 34530139
pii: S1742-7061(21)00600-0
doi: 10.1016/j.actbio.2021.09.012
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
243-253Informations de copyright
Copyright © 2021 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.