Effect of cell culture media on photopolymerizations.


Journal

Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849

Informations de publication

Date de publication:
11 10 2021
Historique:
pubmed: 18 9 2021
medline: 25 2 2023
entrez: 17 9 2021
Statut: ppublish

Résumé

Radical polymerization is one of the most widely used methods for the synthesis of polymeric materials for biomedical applications, such as drug delivery, 3D cell culture, and regenerative medicine. Among radical polymerization reactions, thiol-ene click chemistry has shown excellent orthogonality in diverse reaction conditions. However, our preliminary investigations revealed that it fails in cell culture environment. Herein, we investigate the mechanisms by which cell culture media interfere with radical photoreactions. Three different models including free radical linear photopolymerization (

Identifiants

pubmed: 34533298
doi: 10.1021/acs.biomac.1c00864
doi:

Substances chimiques

Hydrogels 0
Sulfhydryl Compounds 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4295-4305

Auteurs

Marzieh Monfared (M)

School of Chemistry, UNSW, Sydney, NSW 2052, Australia.

Mitchell D Nothling (MD)

School of Chemistry, UNSW, Sydney, NSW 2052, Australia.

Damia Mawad (D)

School of Materials Science and Engineering, UNSW, Sydney, NSW 2052, Australia.

Martina H Stenzel (MH)

School of Chemistry, UNSW, Sydney, NSW 2052, Australia.

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Classifications MeSH