Effect of cell culture media on photopolymerizations.
Journal
Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849
Informations de publication
Date de publication:
11 10 2021
11 10 2021
Historique:
pubmed:
18
9
2021
medline:
25
2
2023
entrez:
17
9
2021
Statut:
ppublish
Résumé
Radical polymerization is one of the most widely used methods for the synthesis of polymeric materials for biomedical applications, such as drug delivery, 3D cell culture, and regenerative medicine. Among radical polymerization reactions, thiol-ene click chemistry has shown excellent orthogonality in diverse reaction conditions. However, our preliminary investigations revealed that it fails in cell culture environment. Herein, we investigate the mechanisms by which cell culture media interfere with radical photoreactions. Three different models including free radical linear photopolymerization (
Identifiants
pubmed: 34533298
doi: 10.1021/acs.biomac.1c00864
doi:
Substances chimiques
Hydrogels
0
Sulfhydryl Compounds
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM