Potential role of dietary chitosan nanoparticles against immunosuppression, inflammation, oxidative stress, and histopathological alterations induced by pendimethalin toxicity in Nile tilapia.
Antioxidant defenses
Chitosan nanoparticles
Histopathological alterations
Immune response
Inflammation
Nile tilapia
Pendimethalin
Journal
Fish & shellfish immunology
ISSN: 1095-9947
Titre abrégé: Fish Shellfish Immunol
Pays: England
ID NLM: 9505220
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
09
07
2021
revised:
13
09
2021
accepted:
15
09
2021
pubmed:
20
9
2021
medline:
24
3
2022
entrez:
19
9
2021
Statut:
ppublish
Résumé
A 21-days feeding screening period was conducted to highlight the protective efficacy of dietary chitosan nanoparticles (CSNPs) on pendimethalin (PD)-induced toxicity in Nile tilapia (Oreochromis niloticus). Hematology, non-specific immune response, the antioxidative enzymes [superoxide dismutase (SOD) and catalase (CAT), glutathione reduced (GSH), and glutathione peroxidase (GPx)] in the liver and anterior kidney, changes of pro-inflammatory cytokine genes [interleukins-8 (IL-8), interleukins-1β (IL-1β), and tumor necrosis-α (TNF-α)] in the anterior kidney and histopathological alterations were assessed. Fish (50 ± 7.5 g) were randomly assigned into four groups (Three replicates), the first group served as the negative control and fed on the control diet only, and the second group served as the positive control and fed on the control diet supplemented with CSNPs (1 g kg
Identifiants
pubmed: 34537335
pii: S1050-4648(21)00281-3
doi: 10.1016/j.fsi.2021.09.015
pii:
doi:
Substances chimiques
Aniline Compounds
0
Antioxidants
0
Chitosan
9012-76-4
pendimethalin
VL6L14C06U
Types de publication
Journal Article
Randomized Controlled Trial, Veterinary
Langues
eng
Sous-ensembles de citation
IM
Pagination
270-282Informations de copyright
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