Separation and non-separation methods for the analysis of cannabinoids in Cannabis sativa L.


Journal

Journal of pharmaceutical and biomedical analysis
ISSN: 1873-264X
Titre abrégé: J Pharm Biomed Anal
Pays: England
ID NLM: 8309336

Informations de publication

Date de publication:
30 Nov 2021
Historique:
received: 30 06 2021
revised: 13 08 2021
accepted: 25 08 2021
pubmed: 20 9 2021
medline: 14 10 2021
entrez: 19 9 2021
Statut: ppublish

Résumé

Cannabis sativa L. is a plant known all over the world, due to its history, bioactivity and also social impact. It is chemically complex with an astonishing ability in the biosynthesis of many secondary metabolites belonging to different chemical classes. Among them, cannabinoids are the most investigated ones, given their pharmacological relevance. In order to monitor the composition of the plant material and ensure the efficacy and safety of its derived products, extraction and analysis of cannabinoids play a crucial role. In this context, in addition to a conventional separation method based on HPLC with UV/DAD detection, a new strategy based on a non-separation procedure, such as

Identifiants

pubmed: 34537622
pii: S0731-7085(21)00457-X
doi: 10.1016/j.jpba.2021.114346
pii:
doi:

Substances chimiques

Cannabinoids 0
Hallucinogens 0
Plant Extracts 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

114346

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Virginia Brighenti (V)

Department of Life Sciences (DSV), University of Modena and Reggio Emilia, Via G. Campi 103, 41125, Modena, Italy.

Lucia Marchetti (L)

Department of Life Sciences (DSV), University of Modena and Reggio Emilia, Via G. Campi 103, 41125, Modena, Italy; Clinical and Experimental Medicine (CEM) PhD Program, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.

Lisa Anceschi (L)

Department of Life Sciences (DSV), University of Modena and Reggio Emilia, Via G. Campi 103, 41125, Modena, Italy; Clinical and Experimental Medicine (CEM) PhD Program, University of Modena and Reggio Emilia, Via G. Campi 287, 41125 Modena, Italy.

Michele Protti (M)

Department of Pharmacy and Biotechnology (FaBiT), Alma Mater Studiorum University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.

Patrizia Verri (P)

Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, Italy.

Federica Pollastro (F)

Department of Pharmaceutical Sciences, University of Eastern Piedmont, Largo Donegani 2, 28100 Novara, Italy.

Laura Mercolini (L)

Department of Pharmacy and Biotechnology (FaBiT), Alma Mater Studiorum University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy.

Davide Bertelli (D)

Department of Life Sciences (DSV), University of Modena and Reggio Emilia, Via G. Campi 103, 41125, Modena, Italy.

Chiara Zanardi (C)

Deparment of Chemical and Geological Sciences (DSCG), University of Modena and Reggio Emilia, Via G. Campi 103, 41125 Modena, Italy.

Federica Pellati (F)

Department of Life Sciences (DSV), University of Modena and Reggio Emilia, Via G. Campi 103, 41125, Modena, Italy. Electronic address: federica.pellati@unimore.it.

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Classifications MeSH