Current and Emerging Medical Therapies for Dizziness.

Dizziness / drug therapy Histamine Antagonists Humans Meniere Disease / drug therapy Migraine Disorders Vertigo
Central vertigo Dizziness Peripheral vertigo Pharmacotherapy

Journal

Otolaryngologic clinics of North America
ISSN: 1557-8259
Titre abrégé: Otolaryngol Clin North Am
Pays: United States
ID NLM: 0144042

Informations de publication

Date de publication:
Oct 2021
Historique:
entrez: 20 9 2021
pubmed: 21 9 2021
medline: 26 11 2021
Statut: ppublish

Résumé

Medical therapies for dizziness are aimed at vertigo reduction, secondary symptom management, or the root cause of the pathologic process. Acute peripheral vertigo pharmacotherapies include antihistamines, calcium channel blockers, and benzodiazepines. Prophylactic pharmacotherapies vary between causes. For Meniere disease, betahistine and diuretics remain initial first-line oral options, whereas intratympanic steroids and intratympanic gentamicin are reserved for uncontrolled symptoms. For cerebellar dizziness and oculomotor disorders, 4-aminopyridine may provide benefit. For vestibular migraine, persistent postural perceptual dizziness and mal de débarquement, treatment options overlap and include selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, tricyclic antidepressants and calcium channel blockers.

Identifiants

DOI: 10.1016/j.otc.2021.05.019 PMID: 34538357
pubmed: 34538357
pii: S0030-6665(21)00120-1
doi: 10.1016/j.otc.2021.05.019
pii:
doi:

Substances chimiques

Histamine Antagonists 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1037-1056

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Mallory J Raymond (MJ)

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue MSC 550, 11th Floor, Charleston, SC 29425, USA.

Esther X Vivas (EX)

Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, 550 Peachtree Street Northeast, 11th Floor, Atlanta, GA 30308, USA. Electronic address: evivas@emory.edu.

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Classifications MeSH

questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Troubles sensitifs › Sensation vertigineuse › Current and Emerging Medical Therapies for Dizziness.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents histaminiques › Antihistaminiques › Current and Emerging Medical Therapies for Dizziness.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Current and Emerging Medical Therapies for Dizziness.
questionsmedicales.fr › Maladies oto-rhino-laryngologiques › Maladies des oreilles › Maladies labyrinthiques › Hydrops endolymphatique › Maladie de Ménière › Current and Emerging Medical Therapies for Dizziness.
questionsmedicales.fr › Maladies du système nerveux › Maladies du système nerveux central › Encéphalopathies › Céphalées › Céphalées primitives › Migraines › Current and Emerging Medical Therapies for Dizziness.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Vertige › Current and Emerging Medical Therapies for Dizziness.