Head and tail rope-assisted recovery improves quality of recovery from general anaesthesia in horses undergoing emergency exploratory laparotomy.


Journal

Equine veterinary journal
ISSN: 2042-3306
Titre abrégé: Equine Vet J
Pays: United States
ID NLM: 0173320

Informations de publication

Date de publication:
Sep 2022
Historique:
revised: 21 07 2021
received: 06 01 2021
accepted: 03 09 2021
pubmed: 21 9 2021
medline: 10 8 2022
entrez: 20 9 2021
Statut: ppublish

Résumé

In equine anaesthesia, the recovery period is critical, accounting for most anaesthesia-related fatalities reported. Horses may recover unassisted or may be assisted, for example, using a head and tail rope recovery method. To compare the impact of head and tail rope and unassisted recovery method on quality of recovery in horses undergoing colic surgery under general anaesthesia (GA). Single centre retrospective cross-sectional study, with prospective model performance analysis. Clinical data were obtained from horses undergoing emergency exploratory laparotomy over a 6-year period. Multivariable logistic regression analysis was used to identify the perioperative factors that affect quality of recovery. The final prediction model was assessed prospectively. Records from 502 general anaesthetics (490 horses) were included. Multivariable logistic regression analysis showed that head and tail rope recovery (OR 2.2, 95% CI 1.4-3.3, P < .001) and sevoflurane administration (OR 1.6, 95% CI 1.2-2.3, P = .02) were associated with better quality of recovery when compared with unassisted recovery and isoflurane administration respectively. Increasing GA duration (OR 1.0, 95% CI 0.99-1.0, P = .03), increasing intraoperative dosages (in mg/kg) of thiopental (OR 0.85, 95% CI 0.75-0.98, P = .02) or ketamine (OR 0.67, 95% CI 0.46-0.99, P = .04) were linked to poor quality of recovery. No statistically significant difference was found between recovery groups in terms of mortality. The clinical prediction model obtained is only applicable to the specific facilities, recovery methodology, referral population and anaesthetic protocols practiced at our institution. Head and tail rope recovery is significantly associated with better quality of recovery, compared with unassisted recovery, in horses undergoing emergency exploratory laparotomy. Sevoflurane administration, in detriment of isoflurane, was associated with better quality of recovery. Other risk factors, such as increasing GA duration, the use of higher intra-operative dosages of ketamine and/or thiopental, were associated with poor quality of recovery.

Sections du résumé

BACKGROUND BACKGROUND
In equine anaesthesia, the recovery period is critical, accounting for most anaesthesia-related fatalities reported. Horses may recover unassisted or may be assisted, for example, using a head and tail rope recovery method.
OBJECTIVES OBJECTIVE
To compare the impact of head and tail rope and unassisted recovery method on quality of recovery in horses undergoing colic surgery under general anaesthesia (GA).
STUDY DESIGN METHODS
Single centre retrospective cross-sectional study, with prospective model performance analysis.
METHODS METHODS
Clinical data were obtained from horses undergoing emergency exploratory laparotomy over a 6-year period. Multivariable logistic regression analysis was used to identify the perioperative factors that affect quality of recovery. The final prediction model was assessed prospectively.
RESULTS RESULTS
Records from 502 general anaesthetics (490 horses) were included. Multivariable logistic regression analysis showed that head and tail rope recovery (OR 2.2, 95% CI 1.4-3.3, P < .001) and sevoflurane administration (OR 1.6, 95% CI 1.2-2.3, P = .02) were associated with better quality of recovery when compared with unassisted recovery and isoflurane administration respectively. Increasing GA duration (OR 1.0, 95% CI 0.99-1.0, P = .03), increasing intraoperative dosages (in mg/kg) of thiopental (OR 0.85, 95% CI 0.75-0.98, P = .02) or ketamine (OR 0.67, 95% CI 0.46-0.99, P = .04) were linked to poor quality of recovery. No statistically significant difference was found between recovery groups in terms of mortality.
MAIN LIMITATIONS CONCLUSIONS
The clinical prediction model obtained is only applicable to the specific facilities, recovery methodology, referral population and anaesthetic protocols practiced at our institution.
CONCLUSIONS CONCLUSIONS
Head and tail rope recovery is significantly associated with better quality of recovery, compared with unassisted recovery, in horses undergoing emergency exploratory laparotomy. Sevoflurane administration, in detriment of isoflurane, was associated with better quality of recovery. Other risk factors, such as increasing GA duration, the use of higher intra-operative dosages of ketamine and/or thiopental, were associated with poor quality of recovery.

Identifiants

pubmed: 34541712
doi: 10.1111/evj.13516
doi:

Substances chimiques

Sevoflurane 38LVP0K73A
Ketamine 690G0D6V8H
Isoflurane CYS9AKD70P
Thiopental JI8Z5M7NA3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

875-884

Informations de copyright

© 2021 EVJ Ltd.

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Auteurs

Luís Filipe Louro (LF)

School of Veterinary Science, Leahurst Campus, University of Liverpool, Neston, Wirral, UK.

Katherine Robson (K)

School of Veterinary Science, Leahurst Campus, University of Liverpool, Neston, Wirral, UK.

Jodie Hughes (J)

North Downs Specialist Referrals, Bletchingley, UK.

Kate Loomes (K)

Rainbow Equine Hospital, Malton, UK.

Mark Senior (M)

School of Veterinary Science, Leahurst Campus, University of Liverpool, Neston, Wirral, UK.

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