Modified Schwartz formula and
Acute kidney injury
Agreement
Children
Glomerular filtration rate
Mortality
Journal
Pediatric nephrology (Berlin, Germany)
ISSN: 1432-198X
Titre abrégé: Pediatr Nephrol
Pays: Germany
ID NLM: 8708728
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
18
01
2021
accepted:
18
06
2021
revised:
18
06
2021
pubmed:
22
9
2021
medline:
10
5
2022
entrez:
21
9
2021
Statut:
ppublish
Résumé
Studies comparing the modified Schwartz formula with measured GFR (m-GFR) are lacking in critically ill children. This prospective cohort study enrolled children aged 1 month to 12 years, within 24 h of admission. m-GFR measured by technetium-99m-labeled diethylenetriaminepentaacetic acid ( A total of 208 pairs were analyzed. e-GFR showed good agreement with m-GFR with a mean bias of -4.37 ml/min/1.73 m The modified Schwartz formula shows good agreement with Protocol accessible at Clinical Trial Registry of India (CTRI) www.ctri.nic.in . (Trial Registered Prospectively and Registration No. CTRI/2017/10/010014) ([Registered on: 06/10/2017] Trial Registered Prospectively.) (Title "Measured glomerular filtration rate using Diethylenetriaminepentaacetic acid (DTPA) renal scan versus estimated glomerular filtration rate using modified Schwartz formula in critically ill children: A prospective observational, analytical study."). A higher resolution version of the Graphical abstract is available as Supplementary information.
Sections du résumé
BACKGROUND
Studies comparing the modified Schwartz formula with measured GFR (m-GFR) are lacking in critically ill children.
METHODS
This prospective cohort study enrolled children aged 1 month to 12 years, within 24 h of admission. m-GFR measured by technetium-99m-labeled diethylenetriaminepentaacetic acid (
RESULTS
A total of 208 pairs were analyzed. e-GFR showed good agreement with m-GFR with a mean bias of -4.37 ml/min/1.73 m
CONCLUSIONS
The modified Schwartz formula shows good agreement with
TRIAL REGISTRATION
Protocol accessible at Clinical Trial Registry of India (CTRI) www.ctri.nic.in . (Trial Registered Prospectively and Registration No. CTRI/2017/10/010014) ([Registered on: 06/10/2017] Trial Registered Prospectively.) (Title "Measured glomerular filtration rate using Diethylenetriaminepentaacetic acid (DTPA) renal scan versus estimated glomerular filtration rate using modified Schwartz formula in critically ill children: A prospective observational, analytical study."). A higher resolution version of the Graphical abstract is available as Supplementary information.
Identifiants
pubmed: 34546418
doi: 10.1007/s00467-021-05197-3
pii: 10.1007/s00467-021-05197-3
doi:
Substances chimiques
Pentetic Acid
7A314HQM0I
Creatinine
AYI8EX34EU
Technetium Tc 99m Pentetate
VW78417PU1
Banques de données
CTRI
['CTRI/2017/10/010014']
Types de publication
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
899-906Informations de copyright
© 2021. IPNA.
Références
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