Extending the straight leg raise test for improved clinical evaluation of sciatica: validity and diagnostic performance with reference to the magnetic resonance imaging.


Journal

BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565

Informations de publication

Date de publication:
21 Sep 2021
Historique:
received: 21 04 2021
accepted: 23 08 2021
entrez: 22 9 2021
pubmed: 23 9 2021
medline: 24 9 2021
Statut: epublish

Résumé

The straight leg raise test (SLR) is one of the most utilized and studied physical tests in patients with low back pain (LBP) for the detection of lumbar disc herniation (LDH), showing high sensitivity and heterogeneous or low specificity. The high incidence of asymptomatic 'pathologic' findings in the magnetic resonance imaging (MRI) scans may cause verification bias to these results. We studied an extended SLR (ESLR) by adding location-specific structural differentiation movements (hip internal rotation or ankle dorsiflexion) to the traditional SLR for it to better differentiate neural symptoms from musculoskeletal. Previously, the ESLR has shown almost perfect interrater reliability between examiners and ability to detect sciatic patients. In this study, we investigated whether a 'positive' ESLR finding is associated with pathology seen on MRI. Forty subjects comprised the study population, 20 in sciatic group and 20 in control group. The ESLR was performed 'blinded' to the subjects. After the ESLR, each subject's lumbar MRI was evaluated. The MRIs were analyzed independently by 2 senior radiologists and a spine specialist clinician. The ESLR and MRI results were cross-tabulated. To obtain the odds ratio (OR) with positive ESLR or SLR results for LDH or nerve root compression (NC), a binary logistic regression analysis with subjects' age, gender, height and weight was performed. ESLR's validity was assessed by combination of interrater agreement and percentage prevalence of both LDH and NC. Of sciatic (ESLR+) patients, 85 % had LDH and 75 % NC in the MRI. Not surprisingly, MRI showed a very high incidence of 'false-positive' findings with the ESLR negative group. The ESLR showed 0.85 sensitivity and 0.45 specificity for LDH and 0.75 sensitivity and 0.50 specificity for NC. A positive result in the ESLR was found to be strongly associated with for both LDH and NC: the OR was 8.0 (p = 0.028) and 5.6 (p = 0.041), respectively. The ESLR shows high validity in detecting neural symptoms and is strongly associated with pathology seen in the MRI when judged positive. We suggest the use of ESLR in clinical practice as a part of clinical examination, where it may prove to be a valuable tool in detecting patients with sciatic symptoms.

Sections du résumé

BACKGROUND BACKGROUND
The straight leg raise test (SLR) is one of the most utilized and studied physical tests in patients with low back pain (LBP) for the detection of lumbar disc herniation (LDH), showing high sensitivity and heterogeneous or low specificity. The high incidence of asymptomatic 'pathologic' findings in the magnetic resonance imaging (MRI) scans may cause verification bias to these results. We studied an extended SLR (ESLR) by adding location-specific structural differentiation movements (hip internal rotation or ankle dorsiflexion) to the traditional SLR for it to better differentiate neural symptoms from musculoskeletal. Previously, the ESLR has shown almost perfect interrater reliability between examiners and ability to detect sciatic patients. In this study, we investigated whether a 'positive' ESLR finding is associated with pathology seen on MRI.
METHODS METHODS
Forty subjects comprised the study population, 20 in sciatic group and 20 in control group. The ESLR was performed 'blinded' to the subjects. After the ESLR, each subject's lumbar MRI was evaluated. The MRIs were analyzed independently by 2 senior radiologists and a spine specialist clinician. The ESLR and MRI results were cross-tabulated. To obtain the odds ratio (OR) with positive ESLR or SLR results for LDH or nerve root compression (NC), a binary logistic regression analysis with subjects' age, gender, height and weight was performed. ESLR's validity was assessed by combination of interrater agreement and percentage prevalence of both LDH and NC.
RESULTS RESULTS
Of sciatic (ESLR+) patients, 85 % had LDH and 75 % NC in the MRI. Not surprisingly, MRI showed a very high incidence of 'false-positive' findings with the ESLR negative group. The ESLR showed 0.85 sensitivity and 0.45 specificity for LDH and 0.75 sensitivity and 0.50 specificity for NC. A positive result in the ESLR was found to be strongly associated with for both LDH and NC: the OR was 8.0 (p = 0.028) and 5.6 (p = 0.041), respectively.
CONCLUSIONS CONCLUSIONS
The ESLR shows high validity in detecting neural symptoms and is strongly associated with pathology seen in the MRI when judged positive. We suggest the use of ESLR in clinical practice as a part of clinical examination, where it may prove to be a valuable tool in detecting patients with sciatic symptoms.

Identifiants

pubmed: 34548049
doi: 10.1186/s12891-021-04649-z
pii: 10.1186/s12891-021-04649-z
pmc: PMC8456642
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

808

Commentaires et corrections

Type : ErratumIn
Type : ErratumIn

Informations de copyright

© 2021. The Author(s).

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Auteurs

Janne Pesonen (J)

Department of Rehabilitation, Kuopio University Hospital, PL 100, 70029, KYS / Kuopio, Finland. janne.pesonen@kuh.fi.
Department of Surgery (incl. Physiatry), University of Eastern Finland, Kuopio, Finland. janne.pesonen@kuh.fi.

Michael Shacklock (M)

Department of Rehabilitation, Kuopio University Hospital, PL 100, 70029, KYS / Kuopio, Finland.
Neurodynamic Solutions, Adelaide, Australia.

Juha-Sampo Suomalainen (JS)

Department of Clinical Radiology, Kuopio University Hospital, Kuopio, Finland.

Lauri Karttunen (L)

Department of Rehabilitation, Kuopio University Hospital, PL 100, 70029, KYS / Kuopio, Finland.
Department of Surgery (incl. Physiatry), University of Eastern Finland, Kuopio, Finland.

Jussi Mäki (J)

Department of Rehabilitation, Kuopio University Hospital, PL 100, 70029, KYS / Kuopio, Finland.

Olavi Airaksinen (O)

Department of Rehabilitation, Kuopio University Hospital, PL 100, 70029, KYS / Kuopio, Finland.
Department of Surgery (incl. Physiatry), University of Eastern Finland, Kuopio, Finland.

Marinko Rade (M)

Department of Rehabilitation, Kuopio University Hospital, PL 100, 70029, KYS / Kuopio, Finland.
Faculty of Medicine, University of Osijek, Orthopaedic and Rehabilitation Hospital "Martin Horvat", Rovinj, Croatia.
Department of Natural and Health Studies, Juraj Dobrila University of Pula, Pula, Croatia.

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Classifications MeSH