A framework to guide dose & regimen strategy for clinical drug development.
Journal
CPT: pharmacometrics & systems pharmacology
ISSN: 2163-8306
Titre abrégé: CPT Pharmacometrics Syst Pharmacol
Pays: United States
ID NLM: 101580011
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
15
06
2021
received:
15
06
2021
accepted:
19
07
2021
pubmed:
26
9
2021
medline:
5
4
2022
entrez:
25
9
2021
Statut:
ppublish
Résumé
Optimizing new drug therapies remains a challenge for clinical development, despite the use of ever more sophisticated quantitative methodologies. Although conceptually simple, the idea of finding the right treatment at the right dose for the right patient to ensure an appropriate balance of risks and benefits is challenging and requires a multidisciplinary approach. In this paper, we present a framework developed as a tool for organizing knowledge and facilitating collaboration in development teams.
Identifiants
pubmed: 34562310
doi: 10.1002/psp4.12701
pmc: PMC8592517
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1276-1280Informations de copyright
© 2021 The Authors. CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals LLC on behalf of American Society for Clinical Pharmacology and Therapeutics.
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CPT Pharmacometrics Syst Pharmacol. 2021 Nov;10(11):1276-1280
pubmed: 34562310