Astrid Jullion

Affiliations

Novartis Institute of Biomedical Research, Basel, Switzerland (B.P., D.P., L.A.L., M.F., A.J., P.S., E.T.C., C.M., C.L., H.M.W.).

Publications (7)

Human Pharmacokinetics of LYS006, an Oral Leukotriene A4 Hydrolase Inhibitor Displaying Target-Mediated Drug Disposition.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Birk Poller , David Pearson , Luc Alexis Leuthold , Martin Fink , Astrid Jullion , Patrick Schweigler , Ester Tor Carreras , Cyrille Marvalin , Christian Loesche , H Markus Weiss

Pharmacokinetic-pharmacodynamic guided optimisation of dose and schedule of CGM097, an HDM2 inhibitor, in preclinical and clinical studies.

British journal of cancer

Avec: Sebastian Bauer , George D Demetri , Ensar Halilovic , Reinhard Dummer , Christophe Meille , Daniel S W Tan , Nelson Guerreiro , Astrid Jullion , Stephane Ferretti , Sebastien Jeay , Laurence Van Bree , Florence Hourcade-Potelleret , Jens U Wuerthner , Claire Fabre , Philippe A Cassier

Co-Targeting of MDM2 and CDK4/6 with Siremadlin and Ribociclib for the Treatment of Patients with Well-Differentiated or Dedifferentiated Liposarcoma: Results from a Proof-of-Concept, Phase Ib Study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Albiruni R Abdul Razak , Sebastian Bauer , Cristina Suarez , Chia-Chi Lin , Richard Quek , Marie Luise Hütter-Krönke , Ricardo Cubedo , Stephane Ferretti , Nelson Guerreiro , Astrid Jullion , Elena J Orlando , Giorgia Clementi , Janna Sand Dejmek , Ensar Halilovic , Claire Fabre , Jean-Yves Blay , Antoine Italiano

Translational Modeling of Anticancer Efficacy to Predict Clinical Outcomes in a First-in-Human Phase 1 Study of MDM2 Inhibitor HDM201.

The AAPS journal

Avec: Nelson Guerreiro , Astrid Jullion , Stephane Ferretti , Claire Fabre , Christophe Meille

A framework to guide dose & regimen strategy for clinical drug development.

CPT: pharmacometrics & systems pharmacology

Avec: Oliver Sander , Baldur Magnusson , Inga Ludwig , Astrid Jullion , Christophe Meille , Daniel Lorand , Björn Bornkamp , Markus Hinder , Steven J Kovacs , Michael Looby

Contribution of machine learning to tumor growth inhibition modeling for hepatocellular carcinoma patients under Roblitinib (FGF401) drug treatment.

CPT: pharmacometrics & systems pharmacology

Avec: Mélanie Wilbaux , David Demanse , Yi Gu , Astrid Jullion , Andrea Myers , Vasiliki Katsanou , Christophe Meille

Integration of Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy into Model-Informed Dose Selection in Oncology First-in-Human Study: A Case of Roblitinib (FGF401).

Clinical pharmacology and therapeutics

Avec: Mélanie Wilbaux , Shu Yang , Astrid Jullion , David Demanse , Diana Graus Porta , Andrea Myers , Christophe Meille , Yi Gu

Réseau de co-auteurs

Christophe Meille 5 collaborations

Nelson Guerreiro 3 collaborations

Stephane Ferretti 3 collaborations

Claire Fabre 3 collaborations

Sebastian Bauer 2 collaborations

Ensar Halilovic 2 collaborations

Mélanie Wilbaux 2 collaborations

David Demanse 2 collaborations

Yi Gu 2 collaborations

Andrea Myers 2 collaborations

Birk Poller 1 collaboration

David Pearson 1 collaboration

Luc Alexis Leuthold 1 collaboration

Martin Fink 1 collaboration

Patrick Schweigler 1 collaboration

Ester Tor Carreras 1 collaboration

Cyrille Marvalin 1 collaboration

Christian Loesche 1 collaboration

H Markus Weiss 1 collaboration

George D Demetri 1 collaboration

Reinhard Dummer 1 collaboration

Daniel S W Tan 1 collaboration

Sebastien Jeay 1 collaboration

Laurence Van Bree 1 collaboration

Florence Hourcade-Potelleret 1 collaboration

Jens U Wuerthner 1 collaboration

Philippe A Cassier 1 collaboration

Albiruni R Abdul Razak 1 collaboration

Cristina Suarez 1 collaboration

Chia-Chi Lin 1 collaboration

Richard Quek 1 collaboration

Marie Luise Hütter-Krönke 1 collaboration

Ricardo Cubedo 1 collaboration

Elena J Orlando 1 collaboration

Giorgia Clementi 1 collaboration

Janna Sand Dejmek 1 collaboration

Jean-Yves Blay 1 collaboration

Antoine Italiano 1 collaboration

Oliver Sander 1 collaboration

Baldur Magnusson 1 collaboration

Inga Ludwig 1 collaboration

Daniel Lorand 1 collaboration

Björn Bornkamp 1 collaboration

Markus Hinder 1 collaboration

Steven J Kovacs 1 collaboration

Michael Looby 1 collaboration

Vasiliki Katsanou 1 collaboration

Shu Yang 1 collaboration

Diana Graus Porta 1 collaboration