New world Leishmania spp. infection in people living with HIV: Concerns about relapses and secondary prophylaxis.
HAART
HIV coinfection
T lymphocytes
Tegumentary leishmaniasis
Visceral leishmaniasis
Journal
Acta tropica
ISSN: 1873-6254
Titre abrégé: Acta Trop
Pays: Netherlands
ID NLM: 0370374
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
19
04
2021
revised:
14
09
2021
accepted:
15
09
2021
pubmed:
26
9
2021
medline:
26
11
2021
entrez:
25
9
2021
Statut:
ppublish
Résumé
Coinfection with the human immunodeficiency virus (HIV) and Leishmania impairs immune responses, increases treatment failure and relapse rates in patients with American tegumentary leishmaniasis (ATL), as well as visceral leishmaniasis (VL). There is insufficient data on the treatment, relapse, and secondary prophylaxis in patients coinfected with HIV/Leishmania in Brazil. This study investigated patients with HIV/ATL and HIV/VL to describe the outcome of leishmaniasis in patients assisted at a referral hospital of Brazilian midwestern region. Patients with HIV/ATL (n = 21) mainly presented cutaneous diseases (76.2%) with an overall relapse rate of 28.57% after treatment, whereas HIV/VL (n = 28) patients accounted for 17.5% of the cases. The counts of CD4
Identifiants
pubmed: 34562423
pii: S0001-706X(21)00325-9
doi: 10.1016/j.actatropica.2021.106146
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
106146Informations de copyright
Copyright © 2021. Published by Elsevier B.V.